A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontiers

Scientific Large Language Models (Sci-LLMs) are transforming how knowledge is represented, integrated, and applied in scientific research, yet their progress is shaped by the complex nature of scientific data. This survey presents a comprehensive, data-centric synthesis that reframes the development of Sci-LLMs as a co-evolution between models and their underlying data substrate. We formulate a unified taxonomy of scientific data and a hierarchical model of scientific knowledge, emphasizing the multimodal, cross-scale, and domain-specific challenges that differentiate scientific corpora from general natural language processing datasets. We systematically review recent Sci-LLMs, from general-purpose foundations to specialized models across diverse scientific disciplines, alongside an extensive analysis of over 270 pre-/post-training datasets, showing why Sci-LLMs pose distinct demands -- heterogeneous, multi-scale, uncertainty-laden corpora that require representations preserving domain invariance and enabling cross-modal reasoning. On evaluation, we examine over 190 benchmark datasets and trace a shift from static exams toward process- and discovery-oriented assessments with advanced evaluation protocols. These data-centric analyses highlight persistent issues in scientific data development and discuss emerging solutions involving semi-automated annotation pipelines and expert validation. Finally, we outline a paradigm shift toward closed-loop systems where autonomous agents based on Sci-LLMs actively experiment, validate, and contribute to a living, evolving knowledge base. Collectively, this work provides a roadmap for building trustworthy, continually evolving artificial intelligence (AI) systems that function as a true partner in accelerating scientific discovery.

Transductive Few-Shot Classification on the Oblique Manifold

Few-shot learning (FSL) attempts to learn with limited data. In this work, we perform the feature extraction in the Euclidean space and the geodesic distance metric on the Oblique Manifold (OM). Specially, for better feature extraction, we propose a non-parametric Region Self-attention with Spatial Pyramid Pooling (RSSPP), which realizes a trade-off between the generalization and the discriminative ability of the single image feature. Then, we embed the feature to OM as a point. Furthermore, we design an Oblique Distance-based Classifier (ODC) that achieves classification in the tangent spaces which better approximate OM locally by learnable tangency points. Finally, we introduce a new method for parameters initialization and a novel loss function in the transductive settings. Extensive experiments demonstrate the effectiveness of our algorithm and it outperforms state-of-the-art methods on the popular benchmarks: mini-ImageNet, tiered-ImageNet, and Caltech-UCSD Birds-200-2011 (CUB).