NGS-Marker: Robust Native Watermarking for 3D Gaussian Splatting

With the rapid development and adoption of 3D Gaussian Splatting (3DGS), the need for effective copyright protection has become increasingly critical. Existing watermarking techniques for 3DGS mainly focus on protecting rendered images via pre-trained decoders, leaving the underlying 3D Gaussian primitives vulnerable to misuse. In particular, they are ineffective against Partial Infringement, where an adversary extracts and reuses only a subset of Gaussians. In this paper, we propose NGS-Marker, a novel native watermarking framework for 3DGS. It integrates a jointly trained watermark injector and message decoder, and employs a gradientbased progressive injection strategy to ensure full-scene coverage. This enables robust ownership decoding from any local region. We further extend NGS-Marker with hybrid protection (combining native and indirect watermarks) and support for multimodal watermarking. Extensive experiments demonstrate that NGS-Marker effectively defends against partial infringement while offering practical flexibility for real-world deployment.

$D^{2}R^{2}$: Discrete Diffusion with Regulation Reinforcement for Single-Cell Perturbation Prediction

Predicting single-cell transcriptomic responses to genetic perturbations is central to functional genomics and virtual-cell modeling. Existing approaches, however, typically predict an entire expression profile as a whole, leaving the order in which individual gene responses are generated unmodeled. To address this problem, we introduce \textbf{$D^{2}R^{2}$} (\textbf{D}iscrete \textbf{D}iffusion with \textbf{R}egulation \textbf{R}einforcement), which reformulates perturbation prediction as regulation-guided gene-wise progressive generation. A Masked Discrete Diffusion Model represents expression as ordinal tokens and reconstructs a fully masked profile step by step, allowing generated gene responses to condition those that remain masked. A Regulatory Policy Module initializes the generation policy from a gene regulatory network inferred from control cells and adapts it to the perturbation and current partially generated state. Then, group-relative policy optimization refines only the ordering policy using final perturbation-effect agreement as reward. Across Norman19 and VCC-H1, $D^{2}R^{2}$ achieves the best performance on all five metrics on Norman19 and remains competitive on H1. Controlled ablations holding the generator and generation budget fixed show that biological-prior ordering improves over random ordering and is more reliable than uncertainty-based heuristics, whereas reversing the biological-prior ordering degrades every metric. Biological analyses further show that the refined policy prioritizes regulatory genes early while promoting perturbation-specific transcription factors and responsive genes. These results establish gene generation order as an effective, controllable, and biologically interpretable dimension of single-cell perturbation prediction.

Variation-aware Flexible 3D Gaussian Editing

Indirect editing methods for 3D Gaussian Splatting (3DGS) have recently witnessed significant advancements. These approaches operate by first applying edits in the rendered 2D space and subsequently projecting the modifications back into 3D. However, this paradigm inevitably introduces cross-view inconsistencies and constrains both the flexibility and efficiency of the editing process. To address these challenges, we present VF-Editor, which enables native editing of Gaussian primitives by predicting attribute variations in a feedforward manner. To accurately and efficiently estimate these variations, we design a novel variation predictor distilled from 2D editing knowledge. The predictor encodes the input to generate a variation field and employs two learnable, parallel decoding functions to iteratively infer attribute changes for each 3D Gaussian. Thanks to its unified design, VF-Editor can seamlessly distill editing knowledge from diverse 2D editors and strategies into a single predictor, allowing for flexible and effective knowledge transfer into the 3D domain. Extensive experiments on both public and private datasets reveal the inherent limitations of indirect editing pipelines and validate the effectiveness and flexibility of our approach.