Few-Shot Learning for Chronic Disease Management: Leveraging Large Language Models and Multi-Prompt Engineering with Medical Knowledge Injection

This study harnesses state-of-the-art AI technology for chronic disease management, specifically in detecting various mental disorders through user-generated textual content. Existing studies typically rely on fully supervised machine learning, which presents challenges such as the labor-intensive manual process of annotating extensive training data for each disease and the need to design specialized deep learning architectures for each problem. To address such challenges, we propose a novel framework that leverages advanced AI techniques, including large language models and multi-prompt engineering. Specifically, we address two key technical challenges in data-driven chronic disease management: (1) developing personalized prompts to represent each user's uniqueness and (2) incorporating medical knowledge into prompts to provide context for chronic disease detection, instruct learning objectives, and operationalize prediction goals. We evaluate our method using four mental disorders, which are prevalent chronic diseases worldwide, as research cases. On the depression detection task, our method (F1 = 0.975~0.978) significantly outperforms traditional supervised learning paradigms, including feature engineering (F1 = 0.760) and architecture engineering (F1 = 0.756). Meanwhile, our approach demonstrates success in few-shot learning, i.e., requiring only a minimal number of training examples to detect chronic diseases based on user-generated textual content (i.e., only 2, 10, or 100 subjects). Moreover, our method can be generalized to other mental disorder detection tasks, including anorexia, pathological gambling, and self-harm (F1 = 0.919~0.978).

Heterogeneous Domain Adaptation with Adversarial Neural Representation Learning: Experiments on E-Commerce and Cybersecurity

Learning predictive models in new domains with scarce training data is a growing challenge in modern supervised learning scenarios. This incentivizes developing domain adaptation methods that leverage the knowledge in known domains (source) and adapt to new domains (target) with a different probability distribution. This becomes more challenging when the source and target domains are in heterogeneous feature spaces, known as heterogeneous domain adaptation (HDA). While most HDA methods utilize mathematical optimization to map source and target data to a common space, they suffer from low transferability. Neural representations have proven to be more transferable; however, they are mainly designed for homogeneous environments. Drawing on the theory of domain adaptation, we propose a novel framework, Heterogeneous Adversarial Neural Domain Adaptation (HANDA), to effectively maximize the transferability in heterogeneous environments. HANDA conducts feature and distribution alignment in a unified neural network architecture and achieves domain invariance through adversarial kernel learning. Three experiments were conducted to evaluate the performance against the state-of-the-art HDA methods on major image and text e-commerce benchmarks. HANDA shows statistically significant improvement in predictive performance. The practical utility of HANDA was shown in real-world dark web online markets. HANDA is an important step towards successful domain adaptation in e-commerce applications.

Understanding Health Misinformation Transmission: An Interpretable Deep Learning Approach to Manage Infodemics

Health misinformation on social media devastates physical and mental health, invalidates health gains, and potentially costs lives. Understanding how health misinformation is transmitted is an urgent goal for researchers, social media platforms, health sectors, and policymakers to mitigate those ramifications. Deep learning methods have been deployed to predict the spread of misinformation. While achieving the state-of-the-art predictive performance, deep learning methods lack the interpretability due to their blackbox nature. To remedy this gap, this study proposes a novel interpretable deep learning approach, Generative Adversarial Network based Piecewise Wide and Attention Deep Learning (GAN-PiWAD), to predict health misinformation transmission in social media. Improving upon state-of-the-art interpretable methods, GAN-PiWAD captures the interactions among multi-modal data, offers unbiased estimation of the total effect of each feature, and models the dynamic total effect of each feature when its value varies. We select features according to social exchange theory and evaluate GAN-PiWAD on 4,445 misinformation videos. The proposed approach outperformed strong benchmarks. Interpretation of GAN-PiWAD indicates video description, negative video content, and channel credibility are key features that drive viral transmission of misinformation. This study contributes to IS with a novel interpretable deep learning method that is generalizable to understand other human decision factors. Our findings provide direct implications for social media platforms and policymakers to design proactive interventions to identify misinformation, control transmissions, and manage infodemics.

TopicModel4J: A Java Package for Topic Models

Topic models provide a flexible and principled framework for exploring hidden structure in high-dimensional co-occurrence data and are commonly used natural language processing (NLP) of text. In this paper, we design and implement a Java package, TopicModel4J, which contains 13 kinds of representative algorithms for fitting topic models. The TopicModel4J in the Java programming environment provides an easy-to-use interface for data analysts to run the algorithms, and allow to easily input and output data. In addition, this package provides a few unstructured text preprocessing techniques, such as splitting textual data into words, lowercasing the words, preforming lemmatization and removing the useless characters, URLs and stop words.

Deep Learning for Information Systems Research

Artificial Intelligence (AI) has rapidly emerged as a key disruptive technology in the 21st century. At the heart of modern AI lies Deep Learning (DL), an emerging class of algorithms that has enabled today's platforms and organizations to operate at unprecedented efficiency, effectiveness, and scale. Despite significant interest, IS contributions in DL have been limited, which we argue is in part due to issues with defining, positioning, and conducting DL research. Recognizing the tremendous opportunity here for the IS community, this work clarifies, streamlines, and presents approaches for IS scholars to make timely and high-impact contributions. Related to this broader goal, this paper makes five timely contributions. First, we systematically summarize the major components of DL in a novel Deep Learning for Information Systems Research (DL-ISR) schematic that illustrates how technical DL processes are driven by key factors from an application environment. Second, we present a novel Knowledge Contribution Framework (KCF) to help IS scholars position their DL contributions for maximum impact. Third, we provide ten guidelines to help IS scholars generate rigorous and relevant DL-ISR in a systematic, high-quality fashion. Fourth, we present a review of prevailing journal and conference venues to examine how IS scholars have leveraged DL for various research inquiries. Finally, we provide a unique perspective on how IS scholars can formulate DL-ISR inquiries by carefully considering the interplay of business function(s), application areas(s), and the KCF. This perspective intentionally emphasizes inter-disciplinary, intra-disciplinary, and cross-IS tradition perspectives. Taken together, these contributions provide IS scholars a timely framework to advance the scale, scope, and impact of deep learning research.