ArSDM: Colonoscopy Images Synthesis with Adaptive Refinement Semantic Diffusion Models

Colonoscopy analysis, particularly automatic polyp segmentation and detection, is essential for assisting clinical diagnosis and treatment. However, as medical image annotation is labour- and resource-intensive, the scarcity of annotated data limits the effectiveness and generalization of existing methods. Although recent research has focused on data generation and augmentation to address this issue, the quality of the generated data remains a challenge, which limits the contribution to the performance of subsequent tasks. Inspired by the superiority of diffusion models in fitting data distributions and generating high-quality data, in this paper, we propose an Adaptive Refinement Semantic Diffusion Model (ArSDM) to generate colonoscopy images that benefit the downstream tasks. Specifically, ArSDM utilizes the ground-truth segmentation mask as a prior condition during training and adjusts the diffusion loss for each input according to the polyp/background size ratio. Furthermore, ArSDM incorporates a pre-trained segmentation model to refine the training process by reducing the difference between the ground-truth mask and the prediction mask. Extensive experiments on segmentation and detection tasks demonstrate the generated data by ArSDM could significantly boost the performance of baseline methods.

Less is More: Adaptive Curriculum Learning for Thyroid Nodule Diagnosis

Thyroid nodule classification aims at determining whether the nodule is benign or malignant based on a given ultrasound image. However, the label obtained by the cytological biopsy which is the golden standard in clinical medicine is not always consistent with the ultrasound imaging TI-RADS criteria. The information difference between the two causes the existing deep learning-based classification methods to be indecisive. To solve the Inconsistent Label problem, we propose an Adaptive Curriculum Learning (ACL) framework, which adaptively discovers and discards the samples with inconsistent labels. Specifically, ACL takes both hard sample and model certainty into account, and could accurately determine the threshold to distinguish the samples with Inconsistent Label. Moreover, we contribute TNCD: a Thyroid Nodule Classification Dataset to facilitate future related research on the thyroid nodules. Extensive experimental results on TNCD based on three different backbone networks not only demonstrate the superiority of our method but also prove that the less-is-more principle which strategically discards the samples with Inconsistent Label could yield performance gains. Source code and data are available at https://github.com/chenghui-666/ACL/.