Explanation supervision aims to enhance deep learning models by integrating additional signals to guide the generation of model explanations, showcasing notable improvements in both the predictability and explainability of the model. However, the application of explanation supervision to higher-dimensional data, such as 3D medical images, remains an under-explored domain. Challenges associated with supervising visual explanations in the presence of an additional dimension include: 1) spatial correlation changed, 2) lack of direct 3D annotations, and 3) uncertainty varies across different parts of the explanation. To address these challenges, we propose a Dynamic Uncertainty-aware Explanation supervision (DUE) framework for 3D explanation supervision that ensures uncertainty-aware explanation guidance when dealing with sparsely annotated 3D data with diffusion-based 3D interpolation. Our proposed framework is validated through comprehensive experiments on diverse real-world medical imaging datasets. The results demonstrate the effectiveness of our framework in enhancing the predictability and explainability of deep learning models in the context of medical imaging diagnosis applications.
Continual Learning is a burgeoning domain in next-generation AI, focusing on training neural networks over a sequence of tasks akin to human learning. While CL provides an edge over traditional supervised learning, its central challenge remains to counteract catastrophic forgetting and ensure the retention of prior tasks during subsequent learning. Amongst various strategies to tackle this, replay based methods have emerged as preeminent, echoing biological memory mechanisms. However, these methods are memory intensive, often preserving entire data samples, an approach inconsistent with humans selective memory retention of salient experiences. While some recent works have explored the storage of only significant portions of data in episodic memory, the inherent nature of partial data necessitates innovative retrieval mechanisms. Current solutions, like inpainting, approximate full data reconstruction from partial cues, a method that diverges from genuine human memory processes. Addressing these nuances, this paper presents the Saliency Guided Hidden Associative Replay for Continual Learning. This novel framework synergizes associative memory with replay-based strategies. SHARC primarily archives salient data segments via sparse memory encoding. Importantly, by harnessing associative memory paradigms, it introduces a content focused memory retrieval mechanism, promising swift and near-perfect recall, bringing CL a step closer to authentic human memory processes. Extensive experimental results demonstrate the effectiveness of our proposed method for various continual learning tasks.