BioMedLM: A 2.7B Parameter Language Model Trained On Biomedical Text

Models such as GPT-4 and Med-PaLM 2 have demonstrated impressive performance on a wide variety of biomedical NLP tasks. However, these models have hundreds of billions of parameters, are computationally expensive to run, require users to send their input data over the internet, and are trained on unknown data sources. Can smaller, more targeted models compete? To address this question, we build and release BioMedLM, a 2.7 billion parameter GPT-style autoregressive model trained exclusively on PubMed abstracts and full articles. When fine-tuned, BioMedLM can produce strong multiple-choice biomedical question-answering results competitive with much larger models, such as achieving a score of 57.3% on MedMCQA (dev) and 69.0% on the MMLU Medical Genetics exam. BioMedLM can also be fine-tuned to produce useful answers to patient questions on medical topics. This demonstrates that smaller models can potentially serve as transparent, privacy-preserving, economical and environmentally friendly foundations for particular NLP applications, such as in biomedicine. The model is available on the Hugging Face Hub: https://huggingface.co/stanford-crfm/BioMedLM.

The Cost of Down-Scaling Language Models: Fact Recall Deteriorates before In-Context Learning

How does scaling the number of parameters in large language models (LLMs) affect their core capabilities? We study two natural scaling techniques -- weight pruning and simply training a smaller or larger model, which we refer to as dense scaling -- and their effects on two core capabilities of LLMs: (a) recalling facts presented during pre-training and (b) processing information presented in-context during inference. By curating a suite of tasks that help disentangle these two capabilities, we find a striking difference in how these two abilities evolve due to scaling. Reducing the model size by more than 30\% (via either scaling approach) significantly decreases the ability to recall facts seen in pre-training. Yet, a 60--70\% reduction largely preserves the various ways the model can process in-context information, ranging from retrieving answers from a long context to learning parameterized functions from in-context exemplars. The fact that both dense scaling and weight pruning exhibit this behavior suggests that scaling model size has an inherently disparate effect on fact recall and in-context learning.

Turaco: Complexity-Guided Data Sampling for Training Neural Surrogates of Programs

Programmers and researchers are increasingly developing surrogates of programs, models of a subset of the observable behavior of a given program, to solve a variety of software development challenges. Programmers train surrogates from measurements of the behavior of a program on a dataset of input examples. A key challenge of surrogate construction is determining what training data to use to train a surrogate of a given program. We present a methodology for sampling datasets to train neural-network-based surrogates of programs. We first characterize the proportion of data to sample from each region of a program's input space (corresponding to different execution paths of the program) based on the complexity of learning a surrogate of the corresponding execution path. We next provide a program analysis to determine the complexity of different paths in a program. We evaluate these results on a range of real-world programs, demonstrating that complexity-guided sampling results in empirical improvements in accuracy.

Computably Continuous Reinforcement-Learning Objectives are PAC-learnable

In reinforcement learning, the classic objectives of maximizing discounted and finite-horizon cumulative rewards are PAC-learnable: There are algorithms that learn a near-optimal policy with high probability using a finite amount of samples and computation. In recent years, researchers have introduced objectives and corresponding reinforcement-learning algorithms beyond the classic cumulative rewards, such as objectives specified as linear temporal logic formulas. However, questions about the PAC-learnability of these new objectives have remained open. This work demonstrates the PAC-learnability of general reinforcement-learning objectives through sufficient conditions for PAC-learnability in two analysis settings. In particular, for the analysis that considers only sample complexity, we prove that if an objective given as an oracle is uniformly continuous, then it is PAC-learnable. Further, for the analysis that considers computational complexity, we prove that if an objective is computable, then it is PAC-learnable. In other words, if a procedure computes successive approximations of the objective's value, then the objective is PAC-learnable. We give three applications of our condition on objectives from the literature with previously unknown PAC-learnability and prove that these objectives are PAC-learnable. Overall, our result helps verify existing objectives' PAC-learnability. Also, as some studied objectives that are not uniformly continuous have been shown to be not PAC-learnable, our results could guide the design of new PAC-learnable objectives.

Acela: Predictable Datacenter-level Maintenance Job Scheduling

Datacenter operators ensure fair and regular server maintenance by using automated processes to schedule maintenance jobs to complete within a strict time budget. Automating this scheduling problem is challenging because maintenance job duration varies based on both job type and hardware. While it is tempting to use prior machine learning techniques for predicting job duration, we find that the structure of the maintenance job scheduling problem creates a unique challenge. In particular, we show that prior machine learning methods that produce the lowest error predictions do not produce the best scheduling outcomes due to asymmetric costs. Specifically, underpredicting maintenance job duration has results in more servers being taken offline and longer server downtime than overpredicting maintenance job duration. The system cost of underprediction is much larger than that of overprediction. We present Acela, a machine learning system for predicting maintenance job duration, which uses quantile regression to bias duration predictions toward overprediction. We integrate Acela into a maintenance job scheduler and evaluate it on datasets from large-scale, production datacenters. Compared to machine learning based predictors from prior work, Acela reduces the number of servers that are taken offline by 1.87-4.28X, and reduces the server offline time by 1.40-2.80X.

Pruning's Effect on Generalization Through the Lens of Training and Regularization

Practitioners frequently observe that pruning improves model generalization. A long-standing hypothesis based on bias-variance trade-off attributes this generalization improvement to model size reduction. However, recent studies on over-parameterization characterize a new model size regime, in which larger models achieve better generalization. Pruning models in this over-parameterized regime leads to a contradiction -- while theory predicts that reducing model size harms generalization, pruning to a range of sparsities nonetheless improves it. Motivated by this contradiction, we re-examine pruning's effect on generalization empirically. We show that size reduction cannot fully account for the generalization-improving effect of standard pruning algorithms. Instead, we find that pruning leads to better training at specific sparsities, improving the training loss over the dense model. We find that pruning also leads to additional regularization at other sparsities, reducing the accuracy degradation due to noisy examples over the dense model. Pruning extends model training time and reduces model size. These two factors improve training and add regularization respectively. We empirically demonstrate that both factors are essential to fully explaining pruning's impact on generalization.

SCOPE: Safe Exploration for Dynamic Computer Systems Optimization

Modern computer systems need to execute under strict safety constraints (e.g., a power limit), but doing so often conflicts with their ability to deliver high performance (i.e. minimal latency). Prior work uses machine learning to automatically tune hardware resources such that the system execution meets safety constraints optimally. Such solutions monitor past system executions to learn the system's behavior under different hardware resource allocations before dynamically tuning resources to optimize the application execution. However, system behavior can change significantly between different applications and even different inputs of the same applications. Hence, the models learned using data collected a priori are often suboptimal and violate safety constraints when used with new applications and inputs. To address this limitation, we introduce the concept of an execution space, which is the cross product of hardware resources, input features, and applications. To dynamically and safely allocate hardware resources from the execution space, we present SCOPE, a resource manager that leverages a novel safe exploration framework. We evaluate SCOPE's ability to deliver improved latency while minimizing power constraint violations by dynamically configuring hardware while running a variety of Apache Spark applications. Compared to prior approaches that minimize power constraint violations, SCOPE consumes comparable power while improving latency by up to 9.5X. Compared to prior approaches that minimize latency, SCOPE achieves similar latency but reduces power constraint violation rates by up to 45.88X, achieving almost zero safety constraint violations across all applications.

Cello: Efficient Computer Systems Optimization with Predictive Early Termination and Censored Regression

Sample-efficient machine learning (SEML) has been widely applied to find optimal latency and power tradeoffs for configurable computer systems. Instead of randomly sampling from the configuration space, SEML reduces the search cost by dramatically reducing the number of configurations that must be sampled to optimize system goals (e.g., low latency or energy). Nevertheless, SEML only reduces one component of cost -- the total number of samples collected -- but does not decrease the cost of collecting each sample. Critically, not all samples are equal; some take much longer to collect because they correspond to slow system configurations. This paper present Cello, a computer systems optimization framework that reduces sample collection costs -- especially those that come from the slowest configurations. The key insight is to predict ahead of time whether samples will have poor system behavior (e.g., long latency or high energy) and terminate these samples early before their measured system behavior surpasses the termination threshold, which we call it predictive early termination. To predict the future system behavior accurately before it manifests as high runtime or energy, Cello uses censored regression to produces accurate predictions for running samples. We evaluate Cello by optimizing latency and energy for Apache Spark workloads. We give Cello a fixed amount of time to search a combined space of hardware and software configuration parameters. Our evaluation shows that compared to the state-of-the-art SEML approach in computer systems optimization, Cello improves latency by 1.19X for minimizing latency under a power constraint, and improves energy by 1.18X for minimizing energy under a latency constraint.

Programming with Neural Surrogates of Programs

Surrogates, models that mimic the behavior of programs, form the basis of a variety of development workflows. We study three surrogate-based design patterns, evaluating each in case studies on a large-scale CPU simulator. With surrogate compilation, programmers develop a surrogate that mimics the behavior of a program to deploy to end-users in place of the original program. Surrogate compilation accelerates the CPU simulator under study by $1.6\times$. With surrogate adaptation, programmers develop a surrogate of a program then retrain that surrogate on a different task. Surrogate adaptation decreases the simulator's error by up to $50\%$. With surrogate optimization, programmers develop a surrogate of a program, optimize input parameters of the surrogate, then plug the optimized input parameters back into the original program. Surrogate optimization finds simulation parameters that decrease the simulator's error by $5\%$ compared to the error induced by expert-set parameters. In this paper we formalize this taxonomy of surrogate-based design patterns. We further describe the programming methodology common to all three design patterns. Our work builds a foundation for the emerging class of workflows based on programming with surrogates of programs.