A novel multistatic multiple-input multiple-output (MIMO) integrated sensing and communication (ISAC) system in cellular networks is proposed. It can make use of widespread base stations (BSs) to perform cooperative sensing in wide area. This system is important since the deployment of sensing function can be achieved based on the existing mobile communication networks at a low cost. In this system, orthogonal frequency division multiplexing (OFDM) signals transmitted from the central BS are received and processed by each of the neighboring BSs to estimate sensing object parameters. A joint data processing method is then introduced to derive the closed-form solution of objects position and velocity. Numerical simulation shows that the proposed multistatic system can improve the position and velocity estimation accuracy compared with monostatic and bistatic system, demonstrating the effectiveness and promise of implementing ISAC in the upcoming fifth generation advanced (5G-A) and sixth generation (6G) mobile networks.