Abstract:3D visuomotor policies offer a promising direction for complex robotic manipulation, as depth maps and point clouds provide rich geometric information for spatial reasoning. However, their success often depends on large-scale real-world demonstrations, which are costly and time-consuming to collect. To this end, existing methods commonly use demonstration generation strategies to improve data efficiency by applying object-centric transformations to human-collected demonstrations, such as varying object poses or scales. While effective for local variation, these transformations largely preserve the original scene structure and skill sequence, limiting their ability to synthesize diverse scene-skill-object combinations for complex tasks. In this paper, we propose Task-Edit, a novel demonstration generation framework that generates diverse trajectories from a task-centric editing perspective. The key insight of Task-Edit is to decompose a task into scene, skill and object components, and flexibly recombine them. In this way, Task-Edit enables scalable demonstration generation and significantly improves generalization for long-horizon manipulation tasks. We evaluate Task-Edit through extensive real-world experiments and demonstrate three advantages: (1) Effectiveness: Task-Edit significantly improves 3D visuomotor policies across various real-world tasks and robot embodiments. (2) Generalizability: Task-Edit improves model generalization across different scenario setups. (3) Applicability: Task-Edit enables models to handle scenarios that are difficult to collect in the real world, including disturbance resistance, obstacle avoidance and unseen cluttered scenes.
Abstract:Magnetically actuated microrobots have been used as wireless, non-contact manipulation tools at microscales, making them promising for minimally invasive applications. However, their control remains challenging due to indirect actuation, limited sensing, and nonlinear magnetic interactions. In this work, we propose Mag-VLA, a vision-language-action (VLA) model for dexterous magnetic microrobot manipulation using two robotic arms with mounted magnets for dynamic magnetic-field construction. Bimanual coordination enables capabilities such as microrobot reorientation that are difficult or infeasible with a single arm, but it also introduces coupled control challenges, as the policy must generate coordinated trajectories for both actuators within a shared workspace. Our framework adapts a Qwen2.5-VL-7B backbone using Low-Rank Adaptation (LoRA) to process visual observations and language instructions for action prediction. To capture task progression, we introduce a motion-aware phase classifier and a phase-conditioned Action Chunking Transformer (ACT) decoder for temporally coherent multi-step control. We further construct a teleoperated magnetic microrobot manipulation dataset covering three task configurations. Ablation studies show that the ACT-based decoder substantially outperforms alternative generative action heads. In real-robot experiments, Mag-VLA achieves a 90% approach success rate across all tasks and transport success rates of 80%, 70%, and 50% as task difficulty increases. These results demonstrate that hierarchical VLA modeling provides a promising framework for magnetic microrobot manipulation.
Abstract:Optical tweezers (OT) provide piconewton-scale manipulation for delicate biomedical tasks, where visuo-haptic feedback can improve operator awareness by conveying interaction-force cues and trap-stability information. However, visuo-haptic teleoperation frameworks for complex-shaped optical microrobots remain underdeveloped, particularly in multi-trap manipulation scenarios. This paper presents a digital twin framework for virtual visuo-haptic teleoperation of complex-shaped OT-driven microrobots. The framework integrates a digital twin environment, image-based pose and depth estimation, microrobot motion simulation, and model-based haptic rendering within a Robot Operating System (ROS)-connected bimanual teleoperation system. For force modeling, we combine a Multi-Sphere Distributed Manipulation (MSDM) model with optical-force estimation from the Optical Tweezers Toolbox, enabling simulator-driven visuo-haptic feedback. The framework reproduces representative microrobot motion trends and provides haptic force rendering that is numerically consistent with the fitted optical-force model. In simulated cell-delivery tasks, haptic feedback reduced the standard deviations of the contact-force metric and the microrobot-to-trap-center distance metric by 53.2% and 55.2%, respectively, and improved task success from 30% to 80%. These results demonstrate the framework's effectiveness for evaluating visuo-haptic teleoperation strategies for complex-shaped optical microrobots.
Abstract:Optical microrobots actuated by optical tweezers (OT) are important for cell manipulation and microscale assembly, but their autonomous operation depends on accurate 3D perception. Developing such perception systems is challenging because large-scale, high-quality microscopy datasets are scarce, owing to complex fabrication processes and labor-intensive annotation. Although generative AI offers a promising route for data augmentation, existing generative adversarial network (GAN)-based methods struggle to reproduce key optical characteristics, particularly depth-dependent diffraction and defocus effects. To address this limitation, we propose Du-FreqNet, a dual-control, frequency-aware diffusion model for physically consistent microscopy image synthesis. The framework features two independent ControlNet branches to encode microrobot 3D point clouds and depth-specific mesh layers, respectively. We introduce an adaptive frequency-domain loss that dynamically reweights high- and low-frequency components based on the distance to the focal plane. By leveraging differentiable FFT-based supervision, Du-FreqNet captures physically meaningful frequency distributions often missed by pixel-space methods. Trained on a limited dataset (e.g., 80 images per pose), our model achieves controllable, depth-dependent image synthesis, improving SSIM by 20.7% over baselines. Extensive experiments demonstrate that Du-FreqNet generalizes effectively to unseen poses and significantly enhances downstream tasks, including 3D pose and depth estimation, thereby facilitating robust closed-loop control in microrobotic systems.
Abstract:Microscale manipulation has advanced substantially in controlled locomotion and targeted transport, yet many biomedical applications require precise and adaptive interaction with biological micro-objects. At these scales, manipulation is realized through three main classes of platforms: embodied microrobots that physically interact as mobile agents, field-mediated systems that generate contactless trapping or manipulation forces, and externally actuated end-effectors that interact through remotely driven physical tools. Unlike macroscale manipulators, these systems function in fluidic, confined, and surface-dominated environments characterized by negligible inertia, dominant interfacial forces, and soft, heterogeneous, and fragile targets. Consequently, classical assumptions of dexterous manipulation, including rigid-body contact, stable grasping, and rich proprioceptive feedback, become difficult to maintain. This review introduces micro-dexterity as a framework for analyzing biological micromanipulation through the coupled roles of embodiment, perception, and control. We examine how classical manipulation primitives, including pushing, reorientation, grasping, and cooperative manipulation, are reformulated at the microscale; compare the architectures that enable them, from contact-based micromanipulators to contactless field-mediated systems and cooperative multi-agent platforms; and review the perception and control strategies required for task execution. We identify the current dexterity gap between laboratory demonstrations and clinically relevant biological manipulation, and outline key challenges for future translation.
Abstract:Acquiring aligned visuo-tactile datasets is slow and costly, requiring specialised hardware and large-scale data collection. Synthetic generation is promising, but prior methods are typically single-modality, limiting cross-modal learning. We present MultiDiffSense, a unified diffusion model that synthesises images for multiple vision-based tactile sensors (ViTac, TacTip, ViTacTip) within a single architecture. Our approach uses dual conditioning on CAD-derived, pose-aligned depth maps and structured prompts that encode sensor type and 4-DoF contact pose, enabling controllable, physically consistent multi-modal synthesis. Evaluating on 8 objects (5 seen, 3 novel) and unseen poses, MultiDiffSense outperforms a Pix2Pix cGAN baseline in SSIM by +36.3% (ViTac), +134.6% (ViTacTip), and +64.7% (TacTip). For downstream 3-DoF pose estimation, mixing 50% synthetic with 50% real halves the required real data while maintaining competitive performance. MultiDiffSense alleviates the data-collection bottleneck in tactile sensing and enables scalable, controllable multi-modal dataset generation for robotic applications.
Abstract:Accurate perception of object hardness is essential for safe and dexterous contact-rich robotic manipulation. Here, we present TactEx, an explainable multimodal robotic interaction framework that unifies vision, touch, and language for human-like hardness estimation and interactive guidance. We evaluate TactEx on fruit-ripeness assessment, a representative task that requires both tactile sensing and contextual understanding. The system fuses GelSight-Mini tactile streams with RGB observations and language prompts. A ResNet50+LSTM model estimates hardness from sequential tactile data, while a cross-modal alignment module combines visual cues with guidance from a large language model (LLM). This explainable multimodal interface allows users to distinguish ripeness levels with statistically significant class separation (p < 0.01 for all fruit pairs). For touch placement, we compare YOLO with Grounded-SAM (GSAM) and find GSAM to be more robust for fine-grained segmentation and contact-site selection. A lightweight LLM parses user instructions and produces grounded natural-language explanations linked to the tactile outputs. In end-to-end evaluations, TactEx attains 90% task success on simple user queries and generalises to novel tasks without large-scale tuning. These results highlight the promise of combining pretrained visual and tactile models with language grounding to advance explainable, human-like touch perception and decision-making in robotics.
Abstract:Parallel diffusion decoding can accelerate diffusion language model inference by unmasking multiple tokens per step, but aggressive parallelism often harms quality. Revocable decoding mitigates this by rechecking earlier tokens, yet we observe that existing verification schemes frequently trigger flip-flop oscillations, where tokens are remasked and later restored unchanged. This behaviour slows inference in two ways: remasking verified positions weakens the conditioning context for parallel drafting, and repeated remask cycles consume the revision budget with little net progress. We propose COVER (Cache Override Verification for Efficient Revision), which performs leave-one-out verification and stable drafting within a single forward pass. COVER constructs two attention views via KV cache override: selected seeds are masked for verification, while their cached key value states are injected for all other queries to preserve contextual information, with a closed form diagonal correction preventing self leakage at the seed positions. COVER further prioritises seeds using a stability aware score that balances uncertainty, downstream influence, and cache drift, and it adapts the number of verified seeds per step. Across benchmarks, COVER markedly reduces unnecessary revisions and yields faster decoding while preserving output quality.
Abstract:Optical microrobots, manipulated via optical tweezers (OT), have broad applications in biomedicine. However, reliable pose and depth perception remain fundamental challenges due to the transparent or low-contrast nature of the microrobots, as well as the noisy and dynamic conditions of the microscale environments in which they operate. An open dataset is crucial for enabling reproducible research, facilitating benchmarking, and accelerating the development of perception models tailored to microscale challenges. Standardised evaluation enables consistent comparison across algorithms, ensuring objective benchmarking and facilitating reproducible research. Here, we introduce the OpTical MicroRobot dataset (OTMR), the first publicly available dataset designed to support microrobot perception under the optical microscope. OTMR contains 232,881 images spanning 18 microrobot types and 176 distinct poses. We benchmarked the performance of eight deep learning models, including architectures derived via neural architecture search (NAS), on two key tasks: pose classification and depth regression. Results indicated that Vision Transformer (ViT) achieve the highest accuracy in pose classification, while depth regression benefits from deeper architectures. Additionally, increasing the size of the training dataset leads to substantial improvements across both tasks, highlighting OTMR's potential as a foundational resource for robust and generalisable microrobot perception in complex microscale environments.




Abstract:In vivo image-guided multi-pipette patch-clamp is essential for studying cellular interactions and network dynamics in neuroscience. However, current procedures mainly rely on manual expertise, which limits accessibility and scalability. Robotic automation presents a promising solution, but achieving precise real-time detection of multiple pipettes remains a challenge. Existing methods focus on ex vivo experiments or single pipette use, making them inadequate for in vivo multi-pipette scenarios. To address these challenges, we propose a heatmap-augmented coarse-to-fine learning technique to facilitate multi-pipette real-time localisation for robot-assisted in vivo patch-clamp. More specifically, we introduce a Generative Adversarial Network (GAN)-based module to remove background noise and enhance pipette visibility. We then introduce a two-stage Transformer model that starts with predicting the coarse heatmap of the pipette tips, followed by the fine-grained coordination regression module for precise tip localisation. To ensure robust training, we use the Hungarian algorithm for optimal matching between the predicted and actual locations of tips. Experimental results demonstrate that our method achieved > 98% accuracy within 10 {\mu}m, and > 89% accuracy within 5 {\mu}m for the localisation of multi-pipette tips. The average MSE is 2.52 {\mu}m.