LEARN: Learned Experts' Assessment-based Reconstruction Network for Sparse-data CT

Compressive sensing (CS) has proved effective for tomographic reconstruction from sparsely collected data or under-sampled measurements, which are practically important for few-view CT, tomosynthesis, interior tomography, and so on. To perform sparse-data CT, the iterative reconstruction commonly use regularizers in the CS framework. Currently, how to choose the parameters adaptively for regularization is a major open problem. In this paper, inspired by the idea of machine learning especially deep learning, we unfold a state-of-the-art "fields of experts" based iterative reconstruction scheme up to a number of iterations for data-driven training, construct a Learned Experts' Assessment-based Reconstruction Network ("LEARN") for sparse-data CT, and demonstrate the feasibility and merits of our LEARN network. The experimental results with our proposed LEARN network produces a competitive performance with the well-known Mayo Clinic Low-Dose Challenge Dataset relative to several state-of-the-art methods, in terms of artifact reduction, feature preservation, and computational speed. This is consistent to our insight that because all the regularization terms and parameters used in the iterative reconstruction are now learned from the training data, our LEARN network utilizes application-oriented knowledge more effectively and recovers underlying images more favorably than competing algorithms. Also, the number of layers in the LEARN network is only 12, reducing the computational complexity of typical iterative algorithms by orders of magnitude.

Low-Dose CT with a Residual Encoder-Decoder Convolutional Neural Network (RED-CNN)

Given the potential X-ray radiation risk to the patient, low-dose CT has attracted a considerable interest in the medical imaging field. The current main stream low-dose CT methods include vendor-specific sinogram domain filtration and iterative reconstruction, but they need to access original raw data whose formats are not transparent to most users. Due to the difficulty of modeling the statistical characteristics in the image domain, the existing methods for directly processing reconstructed images cannot eliminate image noise very well while keeping structural details. Inspired by the idea of deep learning, here we combine the autoencoder, the deconvolution network, and shortcut connections into the residual encoder-decoder convolutional neural network (RED-CNN) for low-dose CT imaging. After patch-based training, the proposed RED-CNN achieves a competitive performance relative to the-state-of-art methods in both simulated and clinical cases. Especially, our method has been favorably evaluated in terms of noise suppression, structural preservation and lesion detection.

Effective face landmark localization via single deep network

In this paper, we propose a novel face alignment method using single deep network (SDN) on existing limited training data. Rather than using a max-pooling layer followed one convolutional layer in typical convolutional neural networks (CNN), SDN adopts a stack of 3 layer groups instead. Each group layer contains two convolutional layers and a max-pooling layer, which can extract the features hierarchically. Moreover, an effective data augmentation strategy and corresponding training skills are also proposed to over-come the lack of training images on COFW and 300-W da-tasets. The experiment results show that our method outper-forms state-of-the-art methods in both detection accuracy and speed.

Low-dose CT denoising with convolutional neural network

To reduce the potential radiation risk, low-dose CT has attracted much attention. However, simply lowering the radiation dose will lead to significant deterioration of the image quality. In this paper, we propose a noise reduction method for low-dose CT via deep neural network without accessing original projection data. A deep convolutional neural network is trained to transform low-dose CT images towards normal-dose CT images, patch by patch. Visual and quantitative evaluation demonstrates a competing performance of the proposed method.