Towards Reliable and Interpretable Traffic Crash Pattern Prediction and Safety Interventions Using Customized Large Language Models

Predicting crash events is crucial for understanding crash distributions and their contributing factors, thereby enabling the design of proactive traffic safety policy interventions. However, existing methods struggle to interpret the complex interplay among various sources of traffic crash data, including numeric characteristics, textual reports, crash imagery, environmental conditions, and driver behavior records. As a result, they often fail to capture the rich semantic information and intricate interrelationships embedded in these diverse data sources, limiting their ability to identify critical crash risk factors. In this research, we propose TrafficSafe, a framework that adapts LLMs to reframe crash prediction and feature attribution as text-based reasoning. A multi-modal crash dataset including 58,903 real-world reports together with belonged infrastructure, environmental, driver, and vehicle information is collected and textualized into TrafficSafe Event Dataset. By customizing and fine-tuning LLMs on this dataset, the TrafficSafe LLM achieves a 42% average improvement in F1-score over baselines. To interpret these predictions and uncover contributing factors, we introduce TrafficSafe Attribution, a sentence-level feature attribution framework enabling conditional risk analysis. Findings show that alcohol-impaired driving is the leading factor in severe crashes, with aggressive and impairment-related behaviors having nearly twice the contribution for severe crashes compared to other driver behaviors. Furthermore, TrafficSafe Attribution highlights pivotal features during model training, guiding strategic crash data collection for iterative performance improvements. The proposed TrafficSafe offers a transformative leap in traffic safety research, providing a blueprint for translating advanced AI technologies into responsible, actionable, and life-saving outcomes.

Can A Society of Generative Agents Simulate Human Behavior and Inform Public Health Policy? A Case Study on Vaccine Hesitancy

Can we simulate a sandbox society with generative agents to model human behavior, thereby reducing the over-reliance on real human trials for assessing public policies? In this work, we investigate the feasibility of simulating health-related decision-making, using vaccine hesitancy, defined as the delay in acceptance or refusal of vaccines despite the availability of vaccination services (MacDonald, 2015), as a case study. To this end, we introduce the VacSim framework with 100 generative agents powered by Large Language Models (LLMs). VacSim simulates vaccine policy outcomes with the following steps: 1) instantiate a population of agents with demographics based on census data; 2) connect the agents via a social network and model vaccine attitudes as a function of social dynamics and disease-related information; 3) design and evaluate various public health interventions aimed at mitigating vaccine hesitancy. To align with real-world results, we also introduce simulation warmup and attitude modulation to adjust agents' attitudes. We propose a series of evaluations to assess the reliability of various LLM simulations. Experiments indicate that models like Llama and Qwen can simulate aspects of human behavior but also highlight real-world alignment challenges, such as inconsistent responses with demographic profiles. This early exploration of LLM-driven simulations is not meant to serve as definitive policy guidance; instead, it serves as a call for action to examine social simulation for policy development.

Advancing Real-time Pandemic Forecasting Using Large Language Models: A COVID-19 Case Study

Forecasting the short-term spread of an ongoing disease outbreak is a formidable challenge due to the complexity of contributing factors, some of which can be characterized through interlinked, multi-modality variables such as epidemiological time series data, viral biology, population demographics, and the intersection of public policy and human behavior. Existing forecasting model frameworks struggle with the multifaceted nature of relevant data and robust results translation, which hinders their performances and the provision of actionable insights for public health decision-makers. Our work introduces PandemicLLM, a novel framework with multi-modal Large Language Models (LLMs) that reformulates real-time forecasting of disease spread as a text reasoning problem, with the ability to incorporate real-time, complex, non-numerical information that previously unattainable in traditional forecasting models. This approach, through a unique AI-human cooperative prompt design and time series representation learning, encodes multi-modal data for LLMs. The model is applied to the COVID-19 pandemic, and trained to utilize textual public health policies, genomic surveillance, spatial, and epidemiological time series data, and is subsequently tested across all 50 states of the U.S. Empirically, PandemicLLM is shown to be a high-performing pandemic forecasting framework that effectively captures the impact of emerging variants and can provide timely and accurate predictions. The proposed PandemicLLM opens avenues for incorporating various pandemic-related data in heterogeneous formats and exhibits performance benefits over existing models. This study illuminates the potential of adapting LLMs and representation learning to enhance pandemic forecasting, illustrating how AI innovations can strengthen pandemic responses and crisis management in the future.