RT-SRTS: Angle-Agnostic Real-Time Simultaneous 3D Reconstruction and Tumor Segmentation from Single X-Ray Projection

Radiotherapy is one of the primary treatment methods for tumors, but the organ movement caused by respiratory motion limits its accuracy. Recently, 3D imaging from single X-ray projection receives extensive attentions as a promising way to address this issue. However, current methods can only reconstruct 3D image without direct location of the tumor and are only validated for fixed-angle imaging, which fails to fully meet the requirement of motion control in radiotherapy. In this study, we propose a novel imaging method RT-SRTS which integrates 3D imaging and tumor segmentation into one network based on the multi-task learning (MTL) and achieves real-time simultaneous 3D reconstruction and tumor segmentation from single X-ray projection at any angle. Futhermore, we propose the attention enhanced calibrator (AEC) and uncertain-region elaboration (URE) modules to aid feature extraction and improve segmentation accuracy. We evaluated the proposed method on ten patient cases and compared it with two state-of-the-art methods. Our approach not only delivered superior 3D reconstruction but also demonstrated commendable tumor segmentation results. The simultaneous reconstruction and segmentation could be completed in approximately 70 ms, significantly faster than the required time threshold for real-time tumor tracking. The efficacy of both AEC and URE was also validated through ablation studies.

Spatial Temporal Graph Convolution with Graph Structure Self-learning for Early MCI Detection

Graph neural networks (GNNs) have been successfully applied to early mild cognitive impairment (EMCI) detection, with the usage of elaborately designed features constructed from blood oxygen level-dependent (BOLD) time series. However, few works explored the feasibility of using BOLD signals directly as features. Meanwhile, existing GNN-based methods primarily rely on hand-crafted explicit brain topology as the adjacency matrix, which is not optimal and ignores the implicit topological organization of the brain. In this paper, we propose a spatial temporal graph convolutional network with a novel graph structure self-learning mechanism for EMCI detection. The proposed spatial temporal graph convolution block directly exploits BOLD time series as input features, which provides an interesting view for rsfMRI-based preclinical AD diagnosis. Moreover, our model can adaptively learn the optimal topological structure and refine edge weights with the graph structure self-learning mechanism. Results on the Alzheimer's Disease Neuroimaging Initiative (ADNI) database show that our method outperforms state-of-the-art approaches. Biomarkers consistent with previous studies can be extracted from the model, proving the reliable interpretability of our method.

Transition-based Parsing with Context Enhancement and Future Reward Reranking

This paper presents a novel reranking model, future reward reranking, to re-score the actions in a transition-based parser by using a global scorer. Different to conventional reranking parsing, the model searches for the best dependency tree in all feasible trees constraining by a sequence of actions to get the future reward of the sequence. The scorer is based on a first-order graph-based parser with bidirectional LSTM, which catches different parsing view compared with the transition-based parser. Besides, since context enhancement has shown substantial improvement in the arc-stand transition-based parsing over the parsing accuracy, we implement context enhancement on an arc-eager transition-base parser with stack LSTMs, the dynamic oracle and dropout supporting and achieve further improvement. With the global scorer and context enhancement, the results show that UAS of the parser increases as much as 1.20% for English and 1.66% for Chinese, and LAS increases as much as 1.32% for English and 1.63% for Chinese. Moreover, we get state-of-the-art LASs, achieving 87.58% for Chinese and 93.37% for English.