NanoResearch: Co-Evolving Skills, Memory, and Policy for Personalized Research Automation

LLM-powered multi-agent systems can now automate the full research pipeline from ideation to paper writing, but a fundamental question remains: automation for whom? Researchers operate under different resource configurations, hold different methodological preferences, and target different output formats. A system that produces uniform outputs regardless of these differences will systematically under-serve every individual user, making personalization a precondition for research automation to be genuinely usable. However, achieving it requires three capabilities that current systems lack: accumulating reusable procedural knowledge across projects, retaining user-specific experience across sessions, and internalizing implicit preferences that resist explicit formalization. We propose NanoResearch, a multi-agent framework that addresses these gaps through tri-level co-evolution. A skill bank distills recurring operations into compact procedural rules reusable across projects. A memory module maintains user- and project-specific experience that grounds planning decisions in each user's research history. A label-free policy learning converts free-form feedback into persistent parameter updates of the planner, reshaping subsequent coordination. These three layers co-evolve: reliable skills produce richer memory, richer memory informs better planning, and preference internalization continuously realigns the loop to each user. Extensive experiments demonstrate that NanoResearch delivers substantial gains over state-of-the-art AI research systems, and progressively refines itself to produce better research at lower cost over successive cycles.

MedFabric and EtHER: A Data-Centric Framework for Word-Level Fabrication Generation and Detection in Medical LLMs

Large Language Models exhibit strong reasoning and semantic understanding capabilities but often hallucinate in domains that require expert knowledge, among which fabrications, the generation of factually incorrect yet fluent statements, pose the greatest risk in medical contexts. Existing medical hallucination datasets inadequately capture fabrication phenomena due to limited fabrication coverage, stylistic disparities between human and LLM-authored texts, and distributional drift during hallucinated sample synthesis. To address this, we propose a data-centric pipeline to generate realistic and word-level fabrications that preserve syntactic and stylistic fidelity while introducing subtle factual deviations, resulting in MedFabric. Building upon this dataset, we introduce ETHER, a modular word-level fabrication detector integrating Text2Table Decomposition, Word Masking and Filling and Hybrid Sentence Pair Evaluation to enhance factual alignment. Empirical results demonstrate that MedFabric outperforms state-of-the-art detectors by over 15% on word-level fabrication benchmarks while maintaining consistent performance across structural similarities, offering a comprehensive framework for reliable and domain-specific factuality detection.

AbLWR:A Context-Aware Listwise Ranking Framework for Antibody-Antigen Binding Affinity Prediction via Positive-Unlabeled Learning

Accurate prediction of antibody-antigen binding affinity is fundamental to therapeutic design, yet remains constrained by severe label sparsity and the complexity of antigenic variations. In this paper, we propose AbLWR (Antibody-antigen binding affinity List-Wise Ranking), a novel framework that reformulates the conventional affinity regression task as a listwise ranking problem. To mitigate label sparsity, AbLWR incorporates a PU (Positive-Unlabeled) learning mechanism leveraging a dual-level contrastive objective and meta-optimized label refinement to learn robust representations. Furthermore, we address antigenic variation by employing a homologous antigen sampling strategy where Multi-Head Self-Attention (MHSA) explicitly models inter-sample relationships within training lists to capture subtle affinity nuances. Extensive experiments demonstrate that AbLWR significantly outperforms state-of-the-art baselines, improving the Precision@1 (P@1) by over 10$\%$ in randomized cross-validation experiments. Notably, case studies on Influenza and IL-33 validate its practical utility, demonstrating robust ranking consistency in distinguishing subtle viral mutations and efficiently prioritizing top-tier candidates for wet-lab screening.

CFMS: A Coarse-to-Fine Multimodal Synthesis Framework for Enhanced Tabular Reasoning

Reasoning over tabular data is a crucial capability for tasks like question answering and fact verification, as it requires models to comprehend both free-form questions and semi-structured tables. However, while methods like Chain-of-Thought (CoT) introduce reasoning chains, purely symbolic methodes are inherently limited by their blindness to holistic visual patterns. To address this, we propose the Coarse-to-Fine Multimodal Synthesis framework (CFMS), a novel two-stage paradigm that hierarchically decouples high-level visual perception from granular symbolic reasoning. In the Coarse Stage, CFMS leverages the Multimodal Large Language Models (MLLMs) to perform a one-time synthesis of a multi-perspective knowledge tuple. This tuple subsequently serves as a dynamic reasoning map to guide the fine stage, where a symbolic engine executes a targeted and efficient sequence of iterative operations over the table. Extensive experiments on the WikiTQ and TabFact benchmarks demonstrate that CFMS achieves competitive accuracy. The framework exhibits particular robustness when handling large tables and when instantiated with smaller backbone models, validating its effectiveness and generalizability.

ProtoFlow: Mitigating Forgetting in Class-Incremental Remote Sensing Segmentation via Low-Curvature Prototype Flow

Remote sensing segmentation in real deployment is inherently continual: new semantic categories emerge, and acquisition conditions shift across seasons, cities, and sensors. Despite recent progress, many incremental approaches still treat training steps as isolated updates, which leaves representation drift and forgetting insufficiently controlled. We present ProtoFlow, a time-aware prototype dynamics framework that models class prototypes as trajectories and learns their evolution with an explicit temporal vector field. By jointly enforcing low-curvature motion and inter-class separation, ProtoFlow stabilizes prototype geometry throughout incremental learning. Experiments on standard class- and domain-incremental remote sensing benchmarks show consistent gains over strong baselines, including up to 1.5-2.0 points improvement in mIoUall, together with reduced forgetting. These results suggest that explicitly modeling temporal prototype evolution is a practical and interpretable strategy for robust continual remote sensing segmentation.

PointRFT: Explicit Reinforcement Fine-tuning for Point Cloud Few-shot Learning

Understanding spatial dynamics and semantics in point cloud is fundamental for comprehensive 3D comprehension. While reinforcement learning algorithms such as Group Relative Policy Optimization (GRPO) have recently achieved remarkable breakthroughs in large language models by incentivizing reasoning capabilities through strategic reward design, their potential remains largely unexplored in the 3D perception domain. This naturally raises a pivotal question: Can RL-based methods effectively empower 3D point cloud fine-tuning? In this paper, we propose PointRFT, the first reinforcement fine-tuning paradigm tailored specifically for point cloud representation learning. We select three prevalent 3D foundation models and devise specialized accuracy reward and dispersion reward functions to stabilize training and mitigate distribution shifts. Through comprehensive few-shot classification experiments comparing distinct training paradigms, we demonstrate that PointRFT consistently outperforms vanilla supervised fine-tuning (SFT) across diverse benchmarks. Furthermore, when organically integrated into a hybrid Pretraining-SFT-RFT paradigm, the representational capacity of point cloud foundation models is substantially unleashed, achieving state-of-the-art performance particularly under data-scarce scenarios.

PersonalQ: Select, Quantize, and Serve Personalized Diffusion Models for Efficient Inference

Personalized text-to-image generation lets users fine-tune diffusion models into repositories of concept-specific checkpoints, but serving these repositories efficiently is difficult for two reasons: natural-language requests are often ambiguous and can be misrouted to visually similar checkpoints, and standard post-training quantization can distort the fragile representations that encode personalized concepts. We present PersonalQ, a unified framework that connects checkpoint selection and quantization through a shared signal -- the checkpoint's trigger token. Check-in performs intent-aligned selection by combining intent-aware hybrid retrieval with LLM-based reranking over checkpoint context and asks a brief clarification question only when multiple intents remain plausible; it then rewrites the prompt by inserting the selected checkpoint's canonical trigger. Complementing this, Trigger-Aware Quantization (TAQ) applies trigger-aware mixed precision in cross-attention, preserving trigger-conditioned key/value rows (and their attention weights) while aggressively quantizing the remaining pathways for memory-efficient inference. Experiments show that PersonalQ improves intent alignment over retrieval and reranking baselines, while TAQ consistently offers a stronger compression-quality trade-off than prior diffusion PTQ methods, enabling scalable serving of personalized checkpoints without sacrificing fidelity.

IGASA: Integrated Geometry-Aware and Skip-Attention Modules for Enhanced Point Cloud Registration

Point cloud registration (PCR) is a fundamental task in 3D vision and provides essential support for applications such as autonomous driving, robotics, and environmental modeling. Despite its widespread use, existing methods often fail when facing real-world challenges like heavy noise, significant occlusions, and large-scale transformations. These limitations frequently result in compromised registration accuracy and insufficient robustness in complex environments. In this paper, we propose IGASA as a novel registration framework constructed upon a Hierarchical Pyramid Architecture (HPA) designed for robust multi-scale feature extraction and fusion. The framework integrates two pivotal components consisting of the Hierarchical Cross-Layer Attention (HCLA) module and the Iterative Geometry-Aware Refinement (IGAR) module. The HCLA module utilizes skip attention mechanisms to align multi-resolution features and enhance local geometric consistency. Simultaneously, the IGAR module is designed for the fine matching phase by leveraging reliable correspondences established during coarse matching. This synergistic integration within the architecture allows IGASA to adapt effectively to diverse point cloud structures and intricate transformations. We evaluate the performance of IGASA on four widely recognized benchmark datasets including 3D(Lo)Match, KITTI, and nuScenes. Our extensive experiments consistently demonstrate that IGASA significantly surpasses state-of-the-art methods and achieves notable improvements in registration accuracy. This work provides a robust foundation for advancing point cloud registration techniques while offering valuable insights for practical 3D vision applications. The code for IGASA is available in \href{https://github.com/DongXu-Zhang/IGASA}{https://github.com/DongXu-Zhang/IGASA}.

CMHANet: A Cross-Modal Hybrid Attention Network for Point Cloud Registration

Robust point cloud registration is a fundamental task in 3D computer vision and geometric deep learning, essential for applications such as large-scale 3D reconstruction, augmented reality, and scene understanding. However, the performance of established learning-based methods often degrades in complex, real world scenarios characterized by incomplete data, sensor noise, and low overlap regions. To address these limitations, we propose CMHANet, a novel Cross-Modal Hybrid Attention Network. Our method integrates the fusion of rich contextual information from 2D images with the geometric detail of 3D point clouds, yielding a comprehensive and resilient feature representation. Furthermore, we introduce an innovative optimization function based on contrastive learning, which enforces geometric consistency and significantly improves the model's robustness to noise and partial observations. We evaluated CMHANet on the 3DMatch and the challenging 3DLoMatch datasets. \rev{Additionally, zero-shot evaluations on the TUM RGB-D SLAM dataset verify the model's generalization capability to unseen domains.} The experimental results demonstrate that our method achieves substantial improvements in both registration accuracy and overall robustness, outperforming current techniques. We also release our code in \href{https://github.com/DongXu-Zhang/CMHANet}{https://github.com/DongXu-Zhang/CMHANet}.

Robust Regularized Policy Iteration under Transition Uncertainty

Offline reinforcement learning (RL) enables data-efficient and safe policy learning without online exploration, but its performance often degrades under distribution shift. The learned policy may visit out-of-distribution state-action pairs where value estimates and learned dynamics are unreliable. To address policy-induced extrapolation and transition uncertainty in a unified framework, we formulate offline RL as robust policy optimization, treating the transition kernel as a decision variable within an uncertainty set and optimizing the policy against the worst-case dynamics. We propose Robust Regularized Policy Iteration (RRPI), which replaces the intractable max-min bilevel objective with a tractable KL-regularized surrogate and derives an efficient policy iteration procedure based on a robust regularized Bellman operator. We provide theoretical guarantees by showing that the proposed operator is a $γ$-contraction and that iteratively updating the surrogate yields monotonic improvement of the original robust objective with convergence. Experiments on D4RL benchmarks demonstrate that RRPI achieves strong average performance, outperforming recent baselines including percentile-based methods such as PMDB on the majority of environments while remaining competitive on the rest. Moreover, RRPI exhibits robust behavior. The learned $Q$-values decrease in regions with higher epistemic uncertainty, suggesting that the resulting policy avoids unreliable out-of-distribution actions under transition uncertainty.