Ammonia-Net: A Multi-task Joint Learning Model for Multi-class Segmentation and Classification in Tooth-marked Tongue Diagnosis

In Traditional Chinese Medicine, the tooth marks on the tongue, stemming from prolonged dental pressure, serve as a crucial indicator for assessing qi (yang) deficiency, which is intrinsically linked to visceral health. Manual diagnosis of tooth-marked tongue solely relies on experience. Nonetheless, the diversity in shape, color, and type of tooth marks poses a challenge to diagnostic accuracy and consistency. To address these problems, herein we propose a multi-task joint learning model named Ammonia-Net. This model employs a convolutional neural network-based architecture, specifically designed for multi-class segmentation and classification of tongue images. Ammonia-Net performs semantic segmentation of tongue images to identify tongue and tooth marks. With the assistance of segmentation output, it classifies the images into the desired number of classes: healthy tongue, light tongue, moderate tongue, and severe tongue. As far as we know, this is the first attempt to apply the semantic segmentation results of tooth marks for tooth-marked tongue classification. To train Ammonia-Net, we collect 856 tongue images from 856 subjects. After a number of extensive experiments, the experimental results show that the proposed model achieves 99.06% accuracy in the two-class classification task of tooth-marked tongue identification and 80.02%. As for the segmentation task, mIoU for tongue and tooth marks amounts to 71.65%.

Neuro-Symbolic Learning: Principles and Applications in Ophthalmology

Neural networks have been rapidly expanding in recent years, with novel strategies and applications. However, challenges such as interpretability, explainability, robustness, safety, trust, and sensibility remain unsolved in neural network technologies, despite the fact that they will unavoidably be addressed for critical applications. Attempts have been made to overcome the challenges in neural network computing by representing and embedding domain knowledge in terms of symbolic representations. Thus, the neuro-symbolic learning (NeSyL) notion emerged, which incorporates aspects of symbolic representation and bringing common sense into neural networks (NeSyL). In domains where interpretability, reasoning, and explainability are crucial, such as video and image captioning, question-answering and reasoning, health informatics, and genomics, NeSyL has shown promising outcomes. This review presents a comprehensive survey on the state-of-the-art NeSyL approaches, their principles, advances in machine and deep learning algorithms, applications such as opthalmology, and most importantly, future perspectives of this emerging field.