CancerGUIDE: Cancer Guideline Understanding via Internal Disagreement Estimation

The National Comprehensive Cancer Network (NCCN) provides evidence-based guidelines for cancer treatment. Translating complex patient presentations into guideline-compliant treatment recommendations is time-intensive, requires specialized expertise, and is prone to error. Advances in large language model (LLM) capabilities promise to reduce the time required to generate treatment recommendations and improve accuracy. We present an LLM agent-based approach to automatically generate guideline-concordant treatment trajectories for patients with non-small cell lung cancer (NSCLC). Our contributions are threefold. First, we construct a novel longitudinal dataset of 121 cases of NSCLC patients that includes clinical encounters, diagnostic results, and medical histories, each expertly annotated with the corresponding NCCN guideline trajectories by board-certified oncologists. Second, we demonstrate that existing LLMs possess domain-specific knowledge that enables high-quality proxy benchmark generation for both model development and evaluation, achieving strong correlation (Spearman coefficient r=0.88, RMSE = 0.08) with expert-annotated benchmarks. Third, we develop a hybrid approach combining expensive human annotations with model consistency information to create both the agent framework that predicts the relevant guidelines for a patient, as well as a meta-classifier that verifies prediction accuracy with calibrated confidence scores for treatment recommendations (AUROC=0.800), a critical capability for communicating the accuracy of outputs, custom-tailoring tradeoffs in performance, and supporting regulatory compliance. This work establishes a framework for clinically viable LLM-based guideline adherence systems that balance accuracy, interpretability, and regulatory requirements while reducing annotation costs, providing a scalable pathway toward automated clinical decision support.

Bias in Gender Bias Benchmarks: How Spurious Features Distort Evaluation

Gender bias in vision-language foundation models (VLMs) raises concerns about their safe deployment and is typically evaluated using benchmarks with gender annotations on real-world images. However, as these benchmarks often contain spurious correlations between gender and non-gender features, such as objects and backgrounds, we identify a critical oversight in gender bias evaluation: Do spurious features distort gender bias evaluation? To address this question, we systematically perturb non-gender features across four widely used benchmarks (COCO-gender, FACET, MIAP, and PHASE) and various VLMs to quantify their impact on bias evaluation. Our findings reveal that even minimal perturbations, such as masking just 10% of objects or weakly blurring backgrounds, can dramatically alter bias scores, shifting metrics by up to 175% in generative VLMs and 43% in CLIP variants. This suggests that current bias evaluations often reflect model responses to spurious features rather than gender bias, undermining their reliability. Since creating spurious feature-free benchmarks is fundamentally challenging, we recommend reporting bias metrics alongside feature-sensitivity measurements to enable a more reliable bias assessment.

MEGG: Replay via Maximally Extreme GGscore in Incremental Learning for Neural Recommendation Models

Neural Collaborative Filtering models are widely used in recommender systems but are typically trained under static settings, assuming fixed data distributions. This limits their applicability in dynamic environments where user preferences evolve. Incremental learning offers a promising solution, yet conventional methods from computer vision or NLP face challenges in recommendation tasks due to data sparsity and distinct task paradigms. Existing approaches for neural recommenders remain limited and often lack generalizability. To address this, we propose MEGG, Replay Samples with Maximally Extreme GGscore, an experience replay based incremental learning framework. MEGG introduces GGscore, a novel metric that quantifies sample influence, enabling the selective replay of highly influential samples to mitigate catastrophic forgetting. Being model-agnostic, MEGG integrates seamlessly across architectures and frameworks. Experiments on three neural models and four benchmark datasets show superior performance over state-of-the-art baselines, with strong scalability, efficiency, and robustness. Implementation will be released publicly upon acceptance.

OCTANE -- Optimal Control for Tensor-based Autoencoder Network Emergence: Explicit Case

This paper presents a novel, mathematically rigorous framework for autoencoder-type deep neural networks that combines optimal control theory and low-rank tensor methods to yield memory-efficient training and automated architecture discovery. The learning task is formulated as an optimization problem constrained by differential equations representing the encoder and decoder components of the network and the corresponding optimality conditions are derived via a Lagrangian approach. Efficient memory compression is enabled by approximating differential equation solutions on low-rank tensor manifolds using an adaptive explicit integration scheme. These concepts are combined to form OCTANE (Optimal Control for Tensor-based Autoencoder Network Emergence) -- a unified training framework that yields compact autoencoder architectures, reduces memory usage, and enables effective learning, even with limited training data. The framework's utility is illustrated with application to image denoising and deblurring tasks and recommendations regarding governing hyperparameters are provided.

Conv4Rec: A 1-by-1 Convolutional AutoEncoder for User Profiling through Joint Analysis of Implicit and Explicit Feedbacks

We introduce a new convolutional AutoEncoder architecture for user modelling and recommendation tasks with several improvements over the state of the art. Firstly, our model has the flexibility to learn a set of associations and combinations between different interaction types in a way that carries over to each user and item. Secondly, our model is able to learn jointly from both the explicit ratings and the implicit information in the sampling pattern (which we refer to as `implicit feedback'). It can also make separate predictions for the probability of consuming content and the likelihood of granting it a high rating if observed. This not only allows the model to make predictions for both the implicit and explicit feedback, but also increases the informativeness of the predictions: in particular, our model can identify items which users would not have been likely to consume naturally, but would be likely to enjoy if exposed to them. Finally, we provide several generalization bounds for our model, which to the best of our knowledge, are among the first generalization bounds for auto-encoders in a Recommender Systems setting; we also show that optimizing our loss function guarantees the recovery of the exact sampling distribution over interactions up to a small error in total variation. In experiments on several real-life datasets, we achieve state-of-the-art performance on both the implicit and explicit feedback prediction tasks despite relying on a single model for both, and benefiting from additional interpretability in the form of individual predictions for the probabilities of each possible rating.

Avoiding Over-Personalization with Rule-Guided Knowledge Graph Adaptation for LLM Recommendations

We present a lightweight neuro-symbolic framework to mitigate over-personalization in LLM-based recommender systems by adapting user-side Knowledge Graphs (KGs) at inference time. Instead of retraining models or relying on opaque heuristics, our method restructures a user's Personalized Knowledge Graph (PKG) to suppress feature co-occurrence patterns that reinforce Personalized Information Environments (PIEs), i.e., algorithmically induced filter bubbles that constrain content diversity. These adapted PKGs are used to construct structured prompts that steer the language model toward more diverse, Out-PIE recommendations while preserving topical relevance. We introduce a family of symbolic adaptation strategies, including soft reweighting, hard inversion, and targeted removal of biased triples, and a client-side learning algorithm that optimizes their application per user. Experiments on a recipe recommendation benchmark show that personalized PKG adaptations significantly increase content novelty while maintaining recommendation quality, outperforming global adaptation and naive prompt-based methods.

Datasets for Navigating Sensitive Topics in Recommendation Systems

Personalized AI systems, from recommendation systems to chatbots, are a prevalent method for distributing content to users based on their learned preferences. However, there is growing concern about the adverse effects of these systems, including their potential tendency to expose users to sensitive or harmful material, negatively impacting overall well-being. To address this concern quantitatively, it is necessary to create datasets with relevant sensitivity labels for content, enabling researchers to evaluate personalized systems beyond mere engagement metrics. To this end, we introduce two novel datasets that include a taxonomy of sensitivity labels alongside user-content ratings: one that integrates MovieLens rating data with content warnings from the Does the Dog Die? community ratings website, and another that combines fan-fiction interaction data and user-generated warnings from Archive of Our Own.

Deep Reinforcement Learning for Ranking Utility Tuning in the Ad Recommender System at Pinterest

The ranking utility function in an ad recommender system, which linearly combines predictions of various business goals, plays a central role in balancing values across the platform, advertisers, and users. Traditional manual tuning, while offering simplicity and interpretability, often yields suboptimal results due to its unprincipled tuning objectives, the vast amount of parameter combinations, and its lack of personalization and adaptability to seasonality. In this work, we propose a general Deep Reinforcement Learning framework for Personalized Utility Tuning (DRL-PUT) to address the challenges of multi-objective optimization within ad recommender systems. Our key contributions include: 1) Formulating the problem as a reinforcement learning task: given the state of an ad request, we predict the optimal hyperparameters to maximize a pre-defined reward. 2) Developing an approach to directly learn an optimal policy model using online serving logs, avoiding the need to estimate a value function, which is inherently challenging due to the high variance and unbalanced distribution of immediate rewards. We evaluated DRL-PUT through an online A/B experiment in Pinterest's ad recommender system. Compared to the baseline manual utility tuning approach, DRL-PUT improved the click-through rate by 9.7% and the long click-through rate by 7.7% on the treated segment. We conducted a detailed ablation study on the impact of different reward definitions and analyzed the personalization aspect of the learned policy model.

Multimodal Foundation Model-Driven User Interest Modeling and Behavior Analysis on Short Video Platforms

With the rapid expansion of user bases on short video platforms, personalized recommendation systems are playing an increasingly critical role in enhancing user experience and optimizing content distribution. Traditional interest modeling methods often rely on unimodal data, such as click logs or text labels, which limits their ability to fully capture user preferences in a complex multimodal content environment. To address this challenge, this paper proposes a multimodal foundation model-based framework for user interest modeling and behavior analysis. By integrating video frames, textual descriptions, and background music into a unified semantic space using cross-modal alignment strategies, the framework constructs fine-grained user interest vectors. Additionally, we introduce a behavior-driven feature embedding mechanism that incorporates viewing, liking, and commenting sequences to model dynamic interest evolution, thereby improving both the timeliness and accuracy of recommendations. In the experimental phase, we conduct extensive evaluations using both public and proprietary short video datasets, comparing our approach against multiple mainstream recommendation algorithms and modeling techniques. Results demonstrate significant improvements in behavior prediction accuracy, interest modeling for cold-start users, and recommendation click-through rates. Moreover, we incorporate interpretability mechanisms using attention weights and feature visualization to reveal the model's decision basis under multimodal inputs and trace interest shifts, thereby enhancing the transparency and controllability of the recommendation system.

Hybrid Matrix Factorization Based Graph Contrastive Learning for Recommendation System

In recent years, methods that combine contrastive learning with graph neural networks have emerged to address the challenges of recommendation systems, demonstrating powerful performance and playing a significant role in this domain. Contrastive learning primarily tackles the issue of data sparsity by employing data augmentation strategies, effectively alleviating this problem and showing promising results. Although existing research has achieved favorable outcomes, most current graph contrastive learning methods are based on two types of data augmentation strategies: the first involves perturbing the graph structure, such as by randomly adding or removing edges; and the second applies clustering techniques. We believe that the interactive information obtained through these two strategies does not fully capture the user-item interactions. In this paper, we propose a novel method called HMFGCL (Hybrid Matrix Factorization Based Graph Contrastive Learning), which integrates two distinct matrix factorization techniques-low-rank matrix factorization (MF) and singular value decomposition (SVD)-to complementarily acquire global collaborative information, thereby constructing enhanced views. Experimental results on multiple public datasets demonstrate that our model outperforms existing baselines, particularly on small-scale datasets.