Medical Visual Prompting (MVP): A Unified Framework for Versatile and High-Quality Medical Image Segmentation

Accurate segmentation of lesion regions is crucial for clinical diagnosis and treatment across various diseases. While deep convolutional networks have achieved satisfactory results in medical image segmentation, they face challenges such as loss of lesion shape information due to continuous convolution and downsampling, as well as the high cost of manually labeling lesions with varying shapes and sizes. To address these issues, we propose a novel medical visual prompting (MVP) framework that leverages pre-training and prompting concepts from natural language processing (NLP). The framework utilizes three key components: Super-Pixel Guided Prompting (SPGP) for superpixelating the input image, Image Embedding Guided Prompting (IEGP) for freezing patch embedding and merging with superpixels to provide visual prompts, and Adaptive Attention Mechanism Guided Prompting (AAGP) for pinpointing prompt content and efficiently adapting all layers. By integrating SPGP, IEGP, and AAGP, the MVP enables the segmentation network to better learn shape prompting information and facilitates mutual learning across different tasks. Extensive experiments conducted on five datasets demonstrate superior performance of this method in various challenging medical image tasks, while simplifying single-task medical segmentation models. This novel framework offers improved performance with fewer parameters and holds significant potential for accurate segmentation of lesion regions in various medical tasks, making it clinically valuable.

LLM Factoscope: Uncovering LLMs' Factual Discernment through Inner States Analysis

Large Language Models (LLMs) have revolutionized various domains with extensive knowledge and creative capabilities. However, a critical issue with LLMs is their tendency to produce outputs that diverge from factual reality. This phenomenon is particularly concerning in sensitive applications such as medical consultation and legal advice, where accuracy is paramount. In this paper, we introduce the LLM factoscope, a novel Siamese network-based model that leverages the inner states of LLMs for factual detection. Our investigation reveals distinguishable patterns in LLMs' inner states when generating factual versus non-factual content. We demonstrate the LLM factoscope's effectiveness across various architectures, achieving over 96% accuracy in factual detection. Our work opens a new avenue for utilizing LLMs' inner states for factual detection and encourages further exploration into LLMs' inner workings for enhanced reliability and transparency.