Decentralized Heterogeneous Multi-Robot Collaborative Exploration for Indoor and Outdoor 3D Environments

Heterogeneous multi-robot systems feature significant adaptability for complex environments. However, effective collaboration that fully exploits the robots' potential remains a core challenge. This paper proposes a decentralized collaborative framework for heterogeneous multi-robot systems to autonomously explore indoor and outdoor 3D environments. First, a basic perception map that integrates terrain and observation metrics is designed. Improved supervoxel segmentation is developed to simplify the map structure and form a high-level representation that supports lightweight communication. Second, the traversal and observation capabilities of heterogeneous robots are modeled to evaluate the requirements of task views derived from incomplete supervoxels. These task views are grouped by requirements and clustered to streamline assignment. Subsequently, the view-cluster assignment is formulated as a heterogeneous multi-depot multi-traveling salesman problem (HMDMTSP) that incorporates constraints between view-cluster requirements and robot capabilities. An improved genetic algorithm is developed to efficiently solve this problem while ensuring global consistency. Based on the assignments, redundant views within clusters are eliminated to refine exploration routes. Finally, conflicts between robots' motion paths are resolved. Simulations and field experiments in cluttered indoor and outdoor environments demonstrate that our approach effectively coordinates exploration tasks among heterogeneous robots, achieving superior exploration efficiency and communication savings compared to state-of-the-art approaches.

Open World Knowledge Aided Single-Cell Foundation Model with Robust Cross-Modal Cell-Language Pre-training

Recent advancements in single-cell multi-omics, particularly RNA-seq, have provided profound insights into cellular heterogeneity and gene regulation. While pre-trained language model (PLM) paradigm based single-cell foundation models have shown promise, they remain constrained by insufficient integration of in-depth individual profiles and neglecting the influence of noise within multi-modal data. To address both issues, we propose an Open-world Language Knowledge-Aided Robust Single-Cell Foundation Model (OKR-CELL). It is built based on a cross-modal Cell-Language pre-training framework, which comprises two key innovations: (1) leveraging Large Language Models (LLMs) based workflow with retrieval-augmented generation (RAG) enriches cell textual descriptions using open-world knowledge; (2) devising a Cross-modal Robust Alignment (CRA) objective that incorporates sample reliability assessment, curriculum learning, and coupled momentum contrastive learning to strengthen the model's resistance to noisy data. After pretraining on 32M cell-text pairs, OKR-CELL obtains cutting-edge results across 6 evaluation tasks. Beyond standard benchmarks such as cell clustering, cell-type annotation, batch-effect correction, and few-shot annotation, the model also demonstrates superior performance in broader multi-modal applications, including zero-shot cell-type annotation and bidirectional cell-text retrieval.