Uncertainty-Aware Multi-View Visual Semantic Embedding

The key challenge in image-text retrieval is effectively leveraging semantic information to measure the similarity between vision and language data. However, using instance-level binary labels, where each image is paired with a single text, fails to capture multiple correspondences between different semantic units, leading to uncertainty in multi-modal semantic understanding. Although recent research has captured fine-grained information through more complex model structures or pre-training techniques, few studies have directly modeled uncertainty of correspondence to fully exploit binary labels. To address this issue, we propose an Uncertainty-Aware Multi-View Visual Semantic Embedding (UAMVSE)} framework that decomposes the overall image-text matching into multiple view-text matchings. Our framework introduce an uncertainty-aware loss function (UALoss) to compute the weighting of each view-text loss by adaptively modeling the uncertainty in each view-text correspondence. Different weightings guide the model to focus on different semantic information, enhancing the model's ability to comprehend the correspondence of images and texts. We also design an optimized image-text matching strategy by normalizing the similarity matrix to improve model performance. Experimental results on the Flicker30k and MS-COCO datasets demonstrate that UAMVSE outperforms state-of-the-art models.

Asymmetric Co-Training with Explainable Cell Graph Ensembling for Histopathological Image Classification

Convolutional neural networks excel in histopathological image classification, yet their pixel-level focus hampers explainability. Conversely, emerging graph convolutional networks spotlight cell-level features and medical implications. However, limited by their shallowness and suboptimal use of high-dimensional pixel data, GCNs underperform in multi-class histopathological image classification. To make full use of pixel-level and cell-level features dynamically, we propose an asymmetric co-training framework combining a deep graph convolutional network and a convolutional neural network for multi-class histopathological image classification. To improve the explainability of the entire framework by embedding morphological and topological distribution of cells, we build a 14-layer deep graph convolutional network to handle cell graph data. For the further utilization and dynamic interactions between pixel-level and cell-level information, we also design a co-training strategy to integrate the two asymmetric branches. Notably, we collect a private clinically acquired dataset termed LUAD7C, including seven subtypes of lung adenocarcinoma, which is rare and more challenging. We evaluated our approach on the private LUAD7C and public colorectal cancer datasets, showcasing its superior performance, explainability, and generalizability in multi-class histopathological image classification.