A Multi-Hypothesis Approach to Color Constancy

Contemporary approaches frame the color constancy problem as learning camera specific illuminant mappings. While high accuracy can be achieved on camera specific data, these models depend on camera spectral sensitivity and typically exhibit poor generalisation to new devices. Additionally, regression methods produce point estimates that do not explicitly account for potential ambiguities among plausible illuminant solutions, due to the ill-posed nature of the problem. We propose a Bayesian framework that naturally handles color constancy ambiguity via a multi-hypothesis strategy. Firstly, we select a set of candidate scene illuminants in a data-driven fashion and apply them to a target image to generate of set of corrected images. Secondly, we estimate, for each corrected image, the likelihood of the light source being achromatic using a camera-agnostic CNN. Finally, our method explicitly learns a final illumination estimate from the generated posterior probability distribution. Our likelihood estimator learns to answer a camera-agnostic question and thus enables effective multi-camera training by disentangling illuminant estimation from the supervised learning task. We extensively evaluate our proposed approach and additionally set a benchmark for novel sensor generalisation without re-training. Our method provides state-of-the-art accuracy on multiple public datasets (up to 11% median angular error improvement) while maintaining real-time execution.

A Multi-Hypothesis Classification Approach to Color Constancy

Contemporary approaches frame the color constancy problem as learning camera specific illuminant mappings. While high accuracy can be achieved on camera specific data, these models depend on camera spectral sensitivity and typically exhibit poor generalisation to new devices. Additionally, regression methods produce point estimates that do not explicitly account for potential ambiguities among plausible illuminant solutions, due to the ill-posed nature of the problem. We propose a Bayesian framework that naturally handles color constancy ambiguity via a multi-hypothesis strategy. Firstly, we select a set of candidate scene illuminants in a data-driven fashion and apply them to a target image to generate of set of corrected images. Secondly, we estimate, for each corrected image, the likelihood of the light source being achromatic using a camera-agnostic CNN. Finally, our method explicitly learns a final illumination estimate from the generated posterior probability distribution. Our likelihood estimator learns to answer a camera-agnostic question and thus enables effective multi-camera training by disentangling illuminant estimation from the supervised learning task. We extensively evaluate our proposed approach and additionally set a benchmark for novel sensor generalisation without re-training. Our method provides state-of-the-art accuracy on multiple public datasets (up to 11% median angular error improvement) while maintaining real-time execution.

SteReFo: Efficient Image Refocusing with Stereo Vision

Whether to attract viewer attention to a particular object, give the impression of depth or simply reproduce human-like scene perception, shallow depth of field images are used extensively by professional and amateur photographers alike. To this end, high quality optical systems are used in DSLR cameras to focus on a specific depth plane while producing visually pleasing bokeh. We propose a physically motivated pipeline to mimic this effect from all-in-focus stereo images, typically retrieved by mobile cameras. It is capable to change the focal plane a posteriori at 76 FPS on KITTI images to enable real-time applications. As our portmanteau suggests, SteReFo interrelates stereo-based depth estimation and refocusing efficiently. In contrast to other approaches, our pipeline is simultaneously fully differentiable, physically motivated, and agnostic to scene content. It also enables computational video focus tracking for moving objects in addition to refocusing of static images. We evaluate our approach on the publicly available datasets SceneFlow, KITTI, CityScapes and quantify the quality of architectural changes.

Meta-Learning for Few-shot Camera-Adaptive Color Constancy

Digital camera pipelines employ color constancy methods to estimate an unknown scene illuminant, enabling the generation of canonical images under an achromatic light source. By taking advantage of large amounts of labelled images, learning-based color constancy methods provide state-of-the-art estimation accuracy. However, for a new sensor, data collection is typically arduous, as it requires both imaging physical calibration objects across different settings (such as indoor and outdoor scenes), as well as manual image annotation to produce ground truth labels. In this work, we address sensor generalisation by framing color constancy as a meta-learning problem. Using an unsupervised strategy driven by color temperature grouping, we define many related, yet distinct, illuminant estimation tasks, aggregating data from four public datasets with different camera sensors and diverse scene content. Experimental results demonstrate it is possible to produce a few-shot color constancy method competitive with the fully-supervised, camera-specific state-of-the-art.

EchoFusion: Tracking and Reconstruction of Objects in 4D Freehand Ultrasound Imaging without External Trackers

Ultrasound (US) is the most widely used fetal imaging technique. However, US images have limited capture range, and suffer from view dependent artefacts such as acoustic shadows. Compounding of overlapping 3D US acquisitions into a high-resolution volume can extend the field of view and remove image artefacts, which is useful for retrospective analysis including population based studies. However, such volume reconstructions require information about relative transformations between probe positions from which the individual volumes were acquired. In prenatal US scans, the fetus can move independently from the mother, making external trackers such as electromagnetic or optical tracking unable to track the motion between probe position and the moving fetus. We provide a novel methodology for image-based tracking and volume reconstruction by combining recent advances in deep learning and simultaneous localisation and mapping (SLAM). Tracking semantics are established through the use of a Residual 3D U-Net and the output is fed to the SLAM algorithm. As a proof of concept, experiments are conducted on US volumes taken from a whole body fetal phantom, and from the heads of real fetuses. For the fetal head segmentation, we also introduce a novel weak annotation approach to minimise the required manual effort for ground truth annotation. We evaluate our method qualitatively, and quantitatively with respect to tissue discrimination accuracy and tracking robustness.

Computing CNN Loss and Gradients for Pose Estimation with Riemannian Geometry

Pose estimation, i.e. predicting a 3D rigid transformation with respect to a fixed co-ordinate frame in, SE(3), is an omnipresent problem in medical image analysis with applications such as: image rigid registration, anatomical standard plane detection, tracking and device/camera pose estimation. Deep learning methods often parameterise a pose with a representation that separates rotation and translation. As commonly available frameworks do not provide means to calculate loss on a manifold, regression is usually performed using the L2-norm independently on the rotation's and the translation's parameterisations, which is a metric for linear spaces that does not take into account the Lie group structure of SE(3). In this paper, we propose a general Riemannian formulation of the pose estimation problem. We propose to train the CNN directly on SE(3) equipped with a left-invariant Riemannian metric, coupling the prediction of the translation and rotation defining the pose. At each training step, the ground truth and predicted pose are elements of the manifold, where the loss is calculated as the Riemannian geodesic distance. We then compute the optimisation direction by back-propagating the gradient with respect to the predicted pose on the tangent space of the manifold SE(3) and update the network weights. We thoroughly evaluate the effectiveness of our loss function by comparing its performance with popular and most commonly used existing methods, on tasks such as image-based localisation and intensity-based 2D/3D registration. We also show that hyper-parameters, used in our loss function to weight the contribution between rotations and translations, can be intrinsically calculated from the dataset to achieve greater performance margins.

Automatic View Planning with Multi-scale Deep Reinforcement Learning Agents

We propose a fully automatic method to find standardized view planes in 3D image acquisitions. Standard view images are important in clinical practice as they provide a means to perform biometric measurements from similar anatomical regions. These views are often constrained to the native orientation of a 3D image acquisition. Navigating through target anatomy to find the required view plane is tedious and operator-dependent. For this task, we employ a multi-scale reinforcement learning (RL) agent framework and extensively evaluate several Deep Q-Network (DQN) based strategies. RL enables a natural learning paradigm by interaction with the environment, which can be used to mimic experienced operators. We evaluate our results using the distance between the anatomical landmarks and detected planes, and the angles between their normal vector and target. The proposed algorithm is assessed on the mid-sagittal and anterior-posterior commissure planes of brain MRI, and the 4-chamber long-axis plane commonly used in cardiac MRI, achieving accuracy of 1.53mm, 1.98mm and 4.84mm, respectively.

Attention U-Net: Learning Where to Look for the Pancreas

We propose a novel attention gate (AG) model for medical imaging that automatically learns to focus on target structures of varying shapes and sizes. Models trained with AGs implicitly learn to suppress irrelevant regions in an input image while highlighting salient features useful for a specific task. This enables us to eliminate the necessity of using explicit external tissue/organ localisation modules of cascaded convolutional neural networks (CNNs). AGs can be easily integrated into standard CNN architectures such as the U-Net model with minimal computational overhead while increasing the model sensitivity and prediction accuracy. The proposed Attention U-Net architecture is evaluated on two large CT abdominal datasets for multi-class image segmentation. Experimental results show that AGs consistently improve the prediction performance of U-Net across different datasets and training sizes while preserving computational efficiency. The code for the proposed architecture is publicly available.

3D Reconstruction in Canonical Co-ordinate Space from Arbitrarily Oriented 2D Images

Limited capture range, and the requirement to provide high quality initialization for optimization-based 2D/3D image registration methods, can significantly degrade the performance of 3D image reconstruction and motion compensation pipelines. Challenging clinical imaging scenarios, which contain significant subject motion such as fetal in-utero imaging, complicate the 3D image and volume reconstruction process. In this paper we present a learning based image registration method capable of predicting 3D rigid transformations of arbitrarily oriented 2D image slices, with respect to a learned canonical atlas co-ordinate system. Only image slice intensity information is used to perform registration and canonical alignment, no spatial transform initialization is required. To find image transformations we utilize a Convolutional Neural Network (CNN) architecture to learn the regression function capable of mapping 2D image slices to a 3D canonical atlas space. We extensively evaluate the effectiveness of our approach quantitatively on simulated Magnetic Resonance Imaging (MRI), fetal brain imagery with synthetic motion and further demonstrate qualitative results on real fetal MRI data where our method is integrated into a full reconstruction and motion compensation pipeline. Our learning based registration achieves an average spatial prediction error of 7 mm on simulated data and produces qualitatively improved reconstructions for heavily moving fetuses with gestational ages of approximately 20 weeks. Our model provides a general and computationally efficient solution to the 2D/3D registration initialization problem and is suitable for real-time scenarios.

Ensembles of Multiple Models and Architectures for Robust Brain Tumour Segmentation

Deep learning approaches such as convolutional neural nets have consistently outperformed previous methods on challenging tasks such as dense, semantic segmentation. However, the various proposed networks perform differently, with behaviour largely influenced by architectural choices and training settings. This paper explores Ensembles of Multiple Models and Architectures (EMMA) for robust performance through aggregation of predictions from a wide range of methods. The approach reduces the influence of the meta-parameters of individual models and the risk of overfitting the configuration to a particular database. EMMA can be seen as an unbiased, generic deep learning model which is shown to yield excellent performance, winning the first position in the BRATS 2017 competition among 50+ participating teams.