Computer Aided Medical Procedures, Technische Universit Munchen, Germany, Johns Hopkins University, Baltimore MD, USA
Abstract:Enabling intuitive, language-driven interaction with surgical scenes is a critical step toward intelligent operating rooms and autonomous surgical robotic assistance. However, the task of referring segmentation, localizing surgical instruments based on natural language descriptions, remains underexplored in surgical videos, with existing approaches struggling to generalize due to reliance on static visual cues and predefined instrument names. In this work, we introduce SurgRef, a novel motion-guided framework that grounds free-form language expressions in instrument motion, capturing how tools move and interact across time, rather than what they look like. This allows models to understand and segment instruments even under occlusion, ambiguity, or unfamiliar terminology. To train and evaluate SurgRef, we present Ref-IMotion, a diverse, multi-institutional video dataset with dense spatiotemporal masks and rich motion-centric expressions. SurgRef achieves state-of-the-art accuracy and generalization across surgical procedures, setting a new benchmark for robust, language-driven surgical video segmentation.
Abstract:Surgical planning integrates visual perception, long-horizon reasoning, and procedural knowledge, yet it remains unclear whether current evaluation protocols reliably assess vision-language models (VLMs) in safety-critical settings. Motivated by a goal-oriented view of surgical planning, we define planning correctness via phase-goal satisfiability, where plan validity is determined by expert-defined surgical rules. Based on this definition, we introduce a multicentric meta-evaluation benchmark with valid procedural variations and invalid plans containing order and content errors. Using this benchmark, we show that sequence similarity metrics systematically misjudge planning quality, penalizing valid plans while failing to identify invalid ones. We therefore adopt a rule-based goal-satisfiability metric as a high-precision meta-evaluation reference to assess Video-LLMs under progressively constrained settings, revealing failures due to perception errors and under-constrained reasoning. Structural knowledge consistently improves performance, whereas semantic guidance alone is unreliable and benefits larger models only when combined with structural constraints.
Abstract:3D pose estimation from sparse multi-views is a critical task for numerous applications, including action recognition, sports analysis, and human-robot interaction. Optimization-based methods typically follow a two-stage pipeline, first detecting 2D keypoints in each view and then associating these detections across views to triangulate the 3D pose. Existing methods rely on mere pairwise associations to model this correspondence problem, treating global consistency between views (i.e., cycle consistency) as a soft constraint. Yet, reconciling these constraints for multiple views becomes brittle when spurious associations propagate errors. We thus propose COMPOSE, a novel framework that formulates multi-view pose correspondence matching as a hypergraph partitioning problem rather than through pairwise association. While the complexity of the resulting integer linear program grows exponentially in theory, we introduce an efficient geometric pruning strategy to substantially reduce the search space. COMPOSE achieves improvements of up to 23% in average precision over previous optimization-based methods and up to 11% over self-supervised end-to-end learned methods, offering a promising solution to a widely studied problem.
Abstract:We propose a monocular depth estimation method based on visual autoregressive (VAR) priors, offering an alternative to diffusion-based approaches. Our method adapts a large-scale text-to-image VAR model and introduces a scale-wise conditional upsampling mechanism with classifier-free guidance. Our approach performs inference in ten fixed autoregressive stages, requiring only 74K synthetic samples for fine-tuning, and achieves competitive results. We report state-of-the-art performance in indoor benchmarks under constrained training conditions, and strong performance when applied to outdoor datasets. This work establishes autoregressive priors as a complementary family of geometry-aware generative models for depth estimation, highlighting advantages in data scalability, and adaptability to 3D vision tasks. Code available at "https://github.com/AmirMaEl/VAR-Depth".




Abstract:Purpose: Detailed surgical recognition is critical for advancing AI-assisted surgery, yet progress is hampered by high annotation costs, data scarcity, and a lack of interpretable models. While scene graphs offer a structured abstraction of surgical events, their full potential remains untapped. In this work, we introduce ProtoFlow, a novel framework that learns dynamic scene graph prototypes to model complex surgical workflows in an interpretable and robust manner. Methods: ProtoFlow leverages a graph neural network (GNN) encoder-decoder architecture that combines self-supervised pretraining for rich representation learning with a prototype-based fine-tuning stage. This process discovers and refines core prototypes that encapsulate recurring, clinically meaningful patterns of surgical interaction, forming an explainable foundation for workflow analysis. Results: We evaluate our approach on the fine-grained CAT-SG dataset. ProtoFlow not only outperforms standard GNN baselines in overall accuracy but also demonstrates exceptional robustness in limited-data, few-shot scenarios, maintaining strong performance when trained on as few as one surgical video. Our qualitative analyses further show that the learned prototypes successfully identify distinct surgical sub-techniques and provide clear, interpretable insights into workflow deviations and rare complications. Conclusion: By uniting robust representation learning with inherent explainability, ProtoFlow represents a significant step toward developing more transparent, reliable, and data-efficient AI systems, accelerating their potential for clinical adoption in surgical training, real-time decision support, and workflow optimization.
Abstract:Specular highlights distort appearance, obscure texture, and hinder geometric reasoning in both natural and surgical imagery. We present UnReflectAnything, an RGB-only framework that removes highlights from a single image by predicting a highlight map together with a reflection-free diffuse reconstruction. The model uses a frozen vision transformer encoder to extract multi-scale features, a lightweight head to localize specular regions, and a token-level inpainting module that restores corrupted feature patches before producing the final diffuse image. To overcome the lack of paired supervision, we introduce a Virtual Highlight Synthesis pipeline that renders physically plausible specularities using monocular geometry, Fresnel-aware shading, and randomized lighting which enables training on arbitrary RGB images with correct geometric structure. UnReflectAnything generalizes across natural and surgical domains where non-Lambertian surfaces and non-uniform lighting create severe highlights and it achieves competitive performance with state-of-the-art results on several benchmarks. Project Page: https://alberto-rota.github.io/UnReflectAnything/
Abstract:Surgical segmentation is pivotal for scene understanding yet remains hindered by annotation scarcity and semantic inconsistency across diverse procedures. Existing approaches typically fine-tune natural foundation models (e.g., SAM) with limited supervision, functioning merely as domain adapters rather than surgical foundation models. Consequently, they struggle to generalize across the vast variability of surgical targets. To bridge this gap, we present LapFM, a foundation model designed to evolve robust segmentation capabilities from massive unlabeled surgical images. Distinct from medical foundation models relying on inefficient self-supervised proxy tasks, LapFM leverages a Hierarchical Concept Evolving Pre-training paradigm. First, we establish a Laparoscopic Concept Hierarchy (LCH) via a hierarchical mask decoder with parent-child query embeddings, unifying diverse entities (i.e., Anatomy, Tissue, and Instrument) into a scalable knowledge structure with cross-granularity semantic consistency. Second, we propose a Confidence-driven Evolving Labeling that iteratively generates and filters pseudo-labels based on hierarchical consistency, progressively incorporating reliable samples from unlabeled images into training. This process yields LapBench-114K, a large-scale benchmark comprising 114K image-mask pairs. Extensive experiments demonstrate that LapFM significantly outperforms state-of-the-art methods, establishing new standards for granularity-adaptive generalization in universal laparoscopic segmentation. The source code is available at https://github.com/xq141839/LapFM.
Abstract:Ultrasound offers a radiation-free, cost-effective solution for real-time visualization of spinal landmarks, paraspinal soft tissues and neurovascular structures, making it valuable for intraoperative guidance during spinal procedures. However, ultrasound suffers from inherent limitations in visualizing complete vertebral anatomy, in particular vertebral bodies, due to acoustic shadowing effects caused by bone. In this work, we present a novel multi-modal deep learning method for completing occluded anatomical structures in 3D ultrasound by leveraging complementary information from a single X-ray image. To enable training, we generate paired training data consisting of: (1) 2D lateral vertebral views that simulate X-ray scans, and (2) 3D partial vertebrae representations that mimic the limited visibility and occlusions encountered during ultrasound spine imaging. Our method integrates morphological information from both imaging modalities and demonstrates significant improvements in vertebral reconstruction (p < 0.001) compared to state of art in 3D ultrasound vertebral completion. We perform phantom studies as an initial step to future clinical translation, and achieve a more accurate, complete volumetric lumbar spine visualization overlayed on the ultrasound scan without the need for registration with preoperative modalities such as computed tomography. This demonstrates that integrating a single X-ray projection mitigates ultrasound's key limitation while preserving its strengths as the primary imaging modality. Code and data can be found at https://github.com/miruna20/US-X-Complete
Abstract:AI-based biomarkers can infer molecular features directly from hematoxylin & eosin (H&E) slides, yet most pathology foundation models (PFMs) rely on global patch-level embeddings and overlook cell-level morphology. We present a PFM model, JWTH (Joint-Weighted Token Hierarchy), which integrates large-scale self-supervised pretraining with cell-centric post-tuning and attention pooling to fuse local and global tokens. Across four tasks involving four biomarkers and eight cohorts, JWTH achieves up to 8.3% higher balanced accuracy and 1.2% average improvement over prior PFMs, advancing interpretable and robust AI-based biomarker detection in digital pathology.
Abstract:Few-shot anomaly detection streamlines and simplifies industrial safety inspection. However, limited samples make accurate differentiation between normal and abnormal features challenging, and even more so under category-agnostic conditions. Large-scale pre-training of foundation visual encoders has advanced many fields, as the enormous quantity of data helps to learn the general distribution of normal images. We observe that the anomaly amount in an image directly correlates with the difference in the learnt embeddings and utilize this to design a few-shot anomaly detector termed FoundAD. This is done by learning a nonlinear projection operator onto the natural image manifold. The simple operator acts as an effective tool for anomaly detection to characterize and identify out-of-distribution regions in an image. Extensive experiments show that our approach supports multi-class detection and achieves competitive performance while using substantially fewer parameters than prior methods. Backed up by evaluations with multiple foundation encoders, including fresh DINOv3, we believe this idea broadens the perspective on foundation features and advances the field of few-shot anomaly detection.