OpenGaFF: Open-Vocabulary Gaussian Feature Field with Codebook Attention

Understanding open-vocabulary 3D scenes with Gaussian-based representations remains challenging due to fragmented and spatially inconsistent semantic predictions across multi-view observations. In this paper, we present OpenGaFF, a novel framework for open-vocabulary 3D scene understanding built upon 3D Gaussian Splatting. At the core of our method is a Gaussian Feature Field that models semantics as a continuous function of Gaussian geometry and appearance. By explicitly conditioning semantic predictions on geometric structure, this formulation strengthens the coupling between geometry and semantics, leading to improved spatial coherence across similar structures in 3D space. To further enforce object-level semantic consistency, we introduce a structured codebook that serves as a set of shared semantic primitives. Furthermore, a codebook-guided attention mechanism is proposed to retrieve language features via similarity matching between query embeddings and learned codebook entries, enabling robust open-vocabulary reasoning while reducing intra-object feature variance. Extensive experiments on standard 2D and 3D open-vocabulary benchmarks demonstrate that our method consistently outperforms prior approaches, achieving improved segmentation quality, stronger 3D semantic consistency and a semantically interpretable codebook that provides insight into the learned representation.

Multivariate Gaussian NeRF for Wide Field-of-View Ultrasound Reconstruction

Wide Field-of-View (WFoV) reconstruction enhances 3D ultrasound imaging by providing valuable anatomical context for segmentation models and visualization. Clinical ultrasound volumes are predominantly acquired using convex probes, which generate expanding, diverging acoustic beams to maximize anatomical coverage. Stitching these sweeps together traditionally introduces significant compounding artifacts and aliasing due to depth-dependent resolution changes. Here, we introduce Ultra-Wide-NeRF, a Multivariate 3D Gaussian (MVG) NeRF-based method for WFoV ultrasound reconstruction. By explicitly modeling the complex beam geometry using distance-dependent convex volumetric sampling and anisotropic 3D Gaussians, our method inherently mitigates these compounding artifacts and provides anti-aliasing. Beyond simply reconstructing a static 3D grid, our NeRF-based approach yields a continuous neural representation of the tissue, enabling the synthesis of high-fidelity novel views from arbitrary virtual trajectories. We validate Ultra-Wide-NeRF for intracardiac echocardiography on phantom and porcine datasets, demonstrating that our method expands the spatial context important in intraoperative navigation. Code will be open-sourced upon publication.

Open-H-Embodiment: A Large-Scale Dataset for Enabling Foundation Models in Medical Robotics

Autonomous medical robots hold promise to improve patient outcomes, reduce provider workload, democratize access to care, and enable superhuman precision. However, autonomous medical robotics has been limited by a fundamental data problem: existing medical robotic datasets are small, single-embodiment, and rarely shared openly, restricting the development of foundation models that the field needs to advance. We introduce Open-H-Embodiment, the largest open dataset of medical robotic video with synchronized kinematics to date, spanning more than 49 institutions and multiple robotic platforms including the CMR Versius, Intuitive Surgical's da Vinci, da Vinci Research Kit (dVRK), Rob Surgical BiTrack, Virtual Incision's MIRA, Moon Surgical Maestro, and a variety of custom systems, spanning surgical manipulation, robotic ultrasound, and endoscopy procedures. We demonstrate the research enabled by this dataset through two foundation models. GR00T-H is the first open foundation vision-language-action model for medical robotics, which is the only evaluated model to achieve full end-to-end task completion on a structured suturing benchmark (25% of trials vs. 0% for all others) and achieves 64% average success across a 29-step ex vivo suturing sequence. We also train Cosmos-H-Surgical-Simulator, the first action-conditioned world model to enable multi-embodiment surgical simulation from a single checkpoint, spanning nine robotic platforms and supporting in silico policy evaluation and synthetic data generation for the medical domain. These results suggest that open, large-scale medical robot data collection can serve as critical infrastructure for the research community, enabling advances in robot learning, world modeling, and beyond.

From Adaptation to Generalization: Adaptive Visual Prompting for Medical Image Segmentation

Visual prompting has emerged as a powerful method for adapting pre-trained models to new domains without updating model parameters. However, existing prompting methods typically optimize a single prompt per domain and apply it uniformly to all inputs, limiting their ability to generalize under intra and inter-domain variability, which is especially critical in the medical field. To address this, we propose APEX, an Adaptive Prompt EXtraction framework that retrieves input-specific prompts from a learnable prompt memory. The memory stores diverse, domain-discriminative prompt representations and is queried via domain features extracted from the Fourier spectrum. To learn robust and discriminative domain features, we introduce a novel Low-Frequency Feature Contrastive (LFC) learning framework that clusters representations from the same domain while separating those from different domains. Extensive experiments on two medical segmentation tasks demonstrate that APEX significantly improves generalization across both seen and unseen domains. Furthermore, it complements any existing backbones and consistently enhances performance, confirming its effectiveness as a plug-and-play prompting solution in medical fields. The code is available at https://github.com/cetinkayaevren/apex/

Dyadic Partnership(DP): A Missing Link Towards Full Autonomy in Medical Robotics

For the past decades medical robotic solutions were mostly based on the concept of tele-manipulation. While their design was extremely intelligent, allowing for better access, improved dexterity, reduced tremor, and improved imaging, their intelligence was limited. They therefore left cognition and decision making to the surgeon. As medical robotics advances towards high-level autonomy, the scientific community needs to explore the required pathway towards partial and full autonomy. Here, we introduce the concept of Dyadic Partnership(DP), a new paradigm in which robots and clinicians engage in intelligent, expert interaction and collaboration. The Dyadic Partners would discuss and agree on decisions and actions during their dynamic and interactive collaboration relying also on intuitive advanced media using generative AI, such as a world model, and advanced multi-modal visualization. This article outlines the foundational components needed to enable such systems, including foundation models for clinical intelligence, multi-modal intent recognition, co-learning frameworks, advanced visualization, and explainable, trust-aware interaction. We further discuss key challenges such as data scarcity, lack of standardization, and ethical acceptance. Dyadic partnership is introduced and is positioned as a powerful yet achievable, acceptable milestone offering a promising pathway toward safer, more intuitive collaboration and a gradual transition to full autonomy across diverse clinical settings.

Energy-based Tissue Manifolds for Longitudinal Multiparametric MRI Analysis

We propose a geometric framework for longitudinal multi-parametric MRI analysis based on patient-specific energy modelling in sequence space. Rather than operating on images with spatial networks, each voxel is represented by its multi-sequence intensity vector ($T1$, $T1c$, $T2$, FLAIR, ADC), and a compact implicit neural representation is trained via denoising score matching to learn an energy function $E_θ(\mathbf{u})$ over $\mathbb{R}^d$ from a single baseline scan. The learned energy landscape provides a differential-geometric description of tissue regimes without segmentation labels. Local minima define tissue basins, gradient magnitude reflects proximity to regime boundaries, and Laplacian curvature characterises local constraint structure. Importantly, this baseline energy manifold is treated as a fixed geometric reference: it encodes the set of contrast combinations observed at diagnosis and is not retrained at follow-up. Longitudinal assessment is therefore formulated as evaluation of subsequent scans relative to this baseline geometry. Rather than comparing anatomical segmentations, we analyse how the distribution of MRI sequence vectors evolves under the baseline energy function. In a paediatric case with later recurrence, follow-up scans show progressive deviation in energy and directional displacement in sequence space toward the baseline tumour-associated regime before clear radiological reappearance. In a case with stable disease, voxel distributions remain confined to established low-energy basins without systematic drift. The presented cases serve as proof-of-concept that patient-specific energy manifolds can function as geometric reference systems for longitudinal mpMRI analysis without explicit segmentation or supervised classification, providing a foundation for further investigation of manifold-based tissue-at-risk tracking in neuro-oncology.

OpenRC: An Open-Source Robotic Colonoscopy Framework for Multimodal Data Acquisition and Autonomy Research

Colorectal cancer screening critically depends on colonoscopy, yet existing platforms offer limited support for systematically studying the coupled dynamics of operator control, instrument motion, and visual feedback. This gap restricts reproducible closed-loop research in robotic colonoscopy, medical imaging, and emerging vision-language-action (VLA) learning paradigms. To address this challenge, we present OpenRC, an open-source modular robotic colonoscopy framework that retrofits conventional scopes while preserving clinical workflow. The framework supports simultaneous recording of video, operator commands, actuation state, and distal tip pose. We experimentally validated motion consistency and quantified cross-modal latency across sensing streams. Using this platform, we collected a multimodal dataset comprising 1,894 teleoperated episodes ~19 hours across 10 structured task variations of routine navigation, failure events, and recovery behaviors. By unifying open hardware and an aligned multimodal dataset, OpenRC provides a reproducible foundation for research in multimodal robotic colonoscopy and surgical autonomy.

Non-Rigid 3D Shape Correspondences: From Foundations to Open Challenges and Opportunities

Estimating correspondences between deformed shape instances is a long-standing problem in computer graphics; numerous applications, from texture transfer to statistical modelling, rely on recovering an accurate correspondence map. Many methods have thus been proposed to tackle this challenging problem from varying perspectives, depending on the downstream application. This state-of-the-art report is geared towards researchers, practitioners, and students seeking to understand recent trends and advances in the field. We categorise developments into three paradigms: spectral methods based on functional maps, combinatorial formulations that impose discrete constraints, and deformation-based methods that directly recover a global alignment. Each school of thought offers different advantages and disadvantages, which we discuss throughout the report. Meanwhile, we highlight the latest developments in each area and suggest new potential research directions. Finally, we provide an overview of emerging challenges and opportunities in this growing field, including the recent use of vision foundation models for zero-shot correspondence and the particularly challenging task of matching partial shapes.

A 4D Representation for Training-Free Agentic Reasoning from Monocular Laparoscopic Video

Spatiotemporal reasoning is a fundamental capability for artificial intelligence (AI) in soft tissue surgery, paving the way for intelligent assistive systems and autonomous robotics. While 2D vision-language models show increasing promise at understanding surgical video, the spatial complexity of surgical scenes suggests that reasoning systems may benefit from explicit 4D representations. Here, we propose a framework for equipping surgical agents with spatiotemporal tools based on an explicit 4D representation, enabling AI systems to ground their natural language reasoning in both time and 3D space. Leveraging models for point tracking, depth, and segmentation, we develop a coherent 4D model with spatiotemporally consistent tool and tissue semantics. A Multimodal Large Language Model (MLLM) then acts as an agent on tools derived from the explicit 4D representation (e.g., trajectories) without any fine-tuning. We evaluate our method on a new dataset of 134 clinically relevant questions and find that the combination of a general purpose reasoning backbone and our 4D representation significantly improves spatiotemporal understanding and allows for 4D grounding. We demonstrate that spatiotemporal intelligence can be "assembled" from 2D MLLMs and 3D computer vision models without additional training. Code, data, and examples are available at https://tum-ai.github.io/surg4d/

Calibrated Confidence Expression for Radiology Report Generation

Safe deployment of Large Vision-Language Models (LVLMs) in radiology report generation requires not only accurate predictions but also clinically interpretable indicators of when outputs should be thoroughly reviewed, enabling selective radiologist verification and reducing the risk of hallucinated findings influencing clinical decisions. One intuitive approach to this is verbalized confidence, where the model explicitly states its certainty. However, current state-of-the-art language models are often overconfident, and research on calibration in multimodal settings such as radiology report generation is limited. To address this gap, we introduce ConRad (Confidence Calibration for Radiology Reports), a reinforcement learning framework for fine-tuning medical LVLMs to produce calibrated verbalized confidence estimates alongside radiology reports. We study two settings: a single report-level confidence score and a sentence-level variant assigning a confidence to each claim. Both are trained using the GRPO algorithm with reward functions based on the logarithmic scoring rule, which incentivizes truthful self-assessment by penalizing miscalibration and guarantees optimal calibration under reward maximization. Experimentally, ConRad substantially improves calibration and outperforms competing methods. In a clinical evaluation we show that ConRad's report level scores are well aligned with clinicians' judgment. By highlighting full reports or low-confidence statements for targeted review, ConRad can support safer clinical integration of AI-assistance for report generation.