Meta-learning In-Context Enables Training-Free Cross Subject Brain Decoding

Visual decoding from brain signals is a key challenge at the intersection of computer vision and neuroscience, requiring methods that bridge neural representations and computational models of vision. A field-wide goal is to achieve generalizable, cross-subject models. A major obstacle towards this goal is the substantial variability in neural representations across individuals, which has so far required training bespoke models or fine-tuning separately for each subject. To address this challenge, we introduce a meta-optimized approach for semantic visual decoding from fMRI that generalizes to novel subjects without any fine-tuning. By simply conditioning on a small set of image-brain activation examples from the new individual, our model rapidly infers their unique neural encoding patterns to facilitate robust and efficient visual decoding. Our approach is explicitly optimized for in-context learning of the new subject's encoding model and performs decoding by hierarchical inference, inverting the encoder. First, for multiple brain regions, we estimate the per-voxel visual response encoder parameters by constructing a context over multiple stimuli and responses. Second, we construct a context consisting of encoder parameters and response values over multiple voxels to perform aggregated functional inversion. We demonstrate strong cross-subject and cross-scanner generalization across diverse visual backbones without retraining or fine-tuning. Moreover, our approach requires neither anatomical alignment nor stimulus overlap. This work is a critical step towards a generalizable foundation model for non-invasive brain decoding.

Meta-Learning an In-Context Transformer Model of Human Higher Visual Cortex

Understanding functional representations within higher visual cortex is a fundamental question in computational neuroscience. While artificial neural networks pretrained on large-scale datasets exhibit striking representational alignment with human neural responses, learning image-computable models of visual cortex relies on individual-level, large-scale fMRI datasets. The necessity for expensive, time-intensive, and often impractical data acquisition limits the generalizability of encoders to new subjects and stimuli. BraInCoRL uses in-context learning to predict voxelwise neural responses from few-shot examples without any additional finetuning for novel subjects and stimuli. We leverage a transformer architecture that can flexibly condition on a variable number of in-context image stimuli, learning an inductive bias over multiple subjects. During training, we explicitly optimize the model for in-context learning. By jointly conditioning on image features and voxel activations, our model learns to directly generate better performing voxelwise models of higher visual cortex. We demonstrate that BraInCoRL consistently outperforms existing voxelwise encoder designs in a low-data regime when evaluated on entirely novel images, while also exhibiting strong test-time scaling behavior. The model also generalizes to an entirely new visual fMRI dataset, which uses different subjects and fMRI data acquisition parameters. Further, BraInCoRL facilitates better interpretability of neural signals in higher visual cortex by attending to semantically relevant stimuli. Finally, we show that our framework enables interpretable mappings from natural language queries to voxel selectivity.

Uni-ISP: Unifying the Learning of ISPs from Multiple Cameras

Modern end-to-end image signal processors (ISPs) can learn complex mappings from RAW/XYZ data to sRGB (or inverse), opening new possibilities in image processing. However, as the diversity of camera models continues to expand, developing and maintaining individual ISPs is not sustainable in the long term, which inherently lacks versatility, hindering the adaptability to multiple camera models. In this paper, we propose a novel pipeline, Uni-ISP, which unifies the learning of ISPs from multiple cameras, offering an accurate and versatile processor to multiple camera models. The core of Uni-ISP is leveraging device-aware embeddings through learning inverse/forward ISPs and its special training scheme. By doing so, Uni-ISP not only improves the performance of inverse/forward ISPs but also unlocks a variety of new applications inaccessible to existing learned ISPs. Moreover, since there is no dataset synchronously captured by multiple cameras for training, we construct a real-world 4K dataset, FiveCam, comprising more than 2,400 pairs of sRGB-RAW images synchronously captured by five smartphones. We conducted extensive experiments demonstrating Uni-ISP's accuracy in inverse/forward ISPs (with improvements of +1.5dB/2.4dB PSNR), its versatility in enabling new applications, and its adaptability to new camera models.