Helper Recommendation with seniority control in Online Health Community

Online health communities (OHCs) are forums where patients with similar conditions communicate their experiences and provide moral support. Social support in OHCs plays a crucial role in easing and rehabilitating patients. However, many time-sensitive questions from patients often remain unanswered due to the multitude of threads and the random nature of patient visits in OHCs. To address this issue, it is imperative to propose a recommender system that assists solution seekers in finding appropriate problem helpers. Nevertheless, developing a recommendation algorithm to enhance social support in OHCs remains an under-explored area. Traditional recommender systems cannot be directly adapted due to the following obstacles. First, unlike user-item links in traditional recommender systems, it is hard to model the social support behind helper-seeker links in OHCs since they are formed based on various heterogeneous reasons. Second, it is difficult to distinguish the impact of historical activities in characterizing patients. Third, it is significantly challenging to ensure that the recommended helpers possess sufficient expertise to assist the seekers. To tackle the aforementioned challenges, we develop a Monotonically regularIzed diseNTangled Variational Autoencoders (MINT) model to strengthen social support in OHCs.

Benchmarking Robustness and Generalization in Multi-Agent Systems: A Case Study on Neural MMO

We present the results of the second Neural MMO challenge, hosted at IJCAI 2022, which received 1600+ submissions. This competition targets robustness and generalization in multi-agent systems: participants train teams of agents to complete a multi-task objective against opponents not seen during training. The competition combines relatively complex environment design with large numbers of agents in the environment. The top submissions demonstrate strong success on this task using mostly standard reinforcement learning (RL) methods combined with domain-specific engineering. We summarize the competition design and results and suggest that, as an academic community, competitions may be a powerful approach to solving hard problems and establishing a solid benchmark for algorithms. We will open-source our benchmark including the environment wrapper, baselines, a visualization tool, and selected policies for further research.

Feature Attention Network (FA-Net): A Deep-Learning Based Approach for Underwater Single Image Enhancement

Underwater image processing and analysis have been a hotspot of study in recent years, as more emphasis has been focused to underwater monitoring and usage of marine resources. Compared with the open environment, underwater image encountered with more complicated conditions such as light abortion, scattering, turbulence, nonuniform illumination and color diffusion. Although considerable advances and enhancement techniques achieved in resolving these issues, they treat low-frequency information equally across the entire channel, which results in limiting the network's representativeness. We propose a deep learning and feature-attention-based end-to-end network (FA-Net) to solve this problem. In particular, we propose a Residual Feature Attention Block (RFAB), containing the channel attention, pixel attention, and residual learning mechanism with long and short skip connections. RFAB allows the network to focus on learning high-frequency information while skipping low-frequency information on multi-hop connections. The channel and pixel attention mechanism considers each channel's different features and the uneven distribution of haze over different pixels in the image. The experimental results shows that the FA-Net propose by us provides higher accuracy, quantitatively and qualitatively and superiority to previous state-of-the-art methods.

Staleness-Alleviated Distributed GNN Training via Online Dynamic-Embedding Prediction

Despite the recent success of Graph Neural Networks (GNNs), it remains challenging to train GNNs on large-scale graphs due to neighbor explosions. As a remedy, distributed computing becomes a promising solution by leveraging abundant computing resources (e.g., GPU). However, the node dependency of graph data increases the difficulty of achieving high concurrency in distributed GNN training, which suffers from the massive communication overhead. To address it, Historical value approximation is deemed a promising class of distributed training techniques. It utilizes an offline memory to cache historical information (e.g., node embedding) as an affordable approximation of the exact value and achieves high concurrency. However, such benefits come at the cost of involving dated training information, leading to staleness, imprecision, and convergence issues. To overcome these challenges, this paper proposes SAT (Staleness-Alleviated Training), a novel and scalable distributed GNN training framework that reduces the embedding staleness adaptively. The key idea of SAT is to model the GNN's embedding evolution as a temporal graph and build a model upon it to predict future embedding, which effectively alleviates the staleness of the cached historical embedding. We propose an online algorithm to train the embedding predictor and the distributed GNN alternatively and further provide a convergence analysis. Empirically, we demonstrate that SAT can effectively reduce embedding staleness and thus achieve better performance and convergence speed on multiple large-scale graph datasets.

ChatSpot: Bootstrapping Multimodal LLMs via Precise Referring Instruction Tuning

Human-AI interactivity is a critical aspect that reflects the usability of multimodal large language models (MLLMs). However, existing end-to-end MLLMs only allow users to interact with them through language instructions, leading to the limitation of the interactive accuracy and efficiency. In this study, we present precise referring instructions that utilize diverse reference representations such as points and boxes as referring prompts to refer to the special region. This enables MLLMs to focus on the region of interest and achieve finer-grained interaction. Based on precise referring instruction, we propose ChatSpot, a unified end-to-end multimodal large language model that supports diverse forms of interactivity including mouse clicks, drag-and-drop, and drawing boxes, which provides a more flexible and seamless interactive experience. We also construct a multi-grained vision-language instruction-following dataset based on existing datasets and GPT-4 generating. Furthermore, we design a series of evaluation tasks to assess the effectiveness of region recognition and interaction. Experimental results showcase ChatSpot's promising performance.

Designing a Direct Feedback Loop between Humans and Convolutional Neural Networks through Local Explanations

The local explanation provides heatmaps on images to explain how Convolutional Neural Networks (CNNs) derive their output. Due to its visual straightforwardness, the method has been one of the most popular explainable AI (XAI) methods for diagnosing CNNs. Through our formative study (S1), however, we captured ML engineers' ambivalent perspective about the local explanation as a valuable and indispensable envision in building CNNs versus the process that exhausts them due to the heuristic nature of detecting vulnerability. Moreover, steering the CNNs based on the vulnerability learned from the diagnosis seemed highly challenging. To mitigate the gap, we designed DeepFuse, the first interactive design that realizes the direct feedback loop between a user and CNNs in diagnosing and revising CNN's vulnerability using local explanations. DeepFuse helps CNN engineers to systemically search "unreasonable" local explanations and annotate the new boundaries for those identified as unreasonable in a labor-efficient manner. Next, it steers the model based on the given annotation such that the model doesn't introduce similar mistakes. We conducted a two-day study (S2) with 12 experienced CNN engineers. Using DeepFuse, participants made a more accurate and "reasonable" model than the current state-of-the-art. Also, participants found the way DeepFuse guides case-based reasoning can practically improve their current practice. We provide implications for design that explain how future HCI-driven design can move our practice forward to make XAI-driven insights more actionable.

Leveraging GPT-4 for Food Effect Summarization to Enhance Product-Specific Guidance Development via Iterative Prompting

Food effect summarization from New Drug Application (NDA) is an essential component of product-specific guidance (PSG) development and assessment. However, manual summarization of food effect from extensive drug application review documents is time-consuming, which arouses a need to develop automated methods. Recent advances in large language models (LLMs) such as ChatGPT and GPT-4, have demonstrated great potential in improving the effectiveness of automated text summarization, but its ability regarding the accuracy in summarizing food effect for PSG assessment remains unclear. In this study, we introduce a simple yet effective approach, iterative prompting, which allows one to interact with ChatGPT or GPT-4 more effectively and efficiently through multi-turn interaction. Specifically, we propose a three-turn iterative prompting approach to food effect summarization in which the keyword-focused and length-controlled prompts are respectively provided in consecutive turns to refine the quality of the generated summary. We conduct a series of extensive evaluations, ranging from automated metrics to FDA professionals and even evaluation by GPT-4, on 100 NDA review documents selected over the past five years. We observe that the summary quality is progressively improved throughout the process. Moreover, we find that GPT-4 performs better than ChatGPT, as evaluated by FDA professionals (43% vs. 12%) and GPT-4 (64% vs. 35%). Importantly, all the FDA professionals unanimously rated that 85% of the summaries generated by GPT-4 are factually consistent with the golden reference summary, a finding further supported by GPT-4 rating of 72% consistency. These results strongly suggest a great potential for GPT-4 to draft food effect summaries that could be reviewed by FDA professionals, thereby improving the efficiency of PSG assessment cycle and promoting the generic drug product development.

TKDP: Threefold Knowledge-enriched Deep Prompt Tuning for Few-shot Named Entity Recognition

Few-shot named entity recognition (NER) exploits limited annotated instances to identify named mentions. Effectively transferring the internal or external resources thus becomes the key to few-shot NER. While the existing prompt tuning methods have shown remarkable few-shot performances, they still fail to make full use of knowledge. In this work, we investigate the integration of rich knowledge to prompt tuning for stronger few-shot NER. We propose incorporating the deep prompt tuning framework with threefold knowledge (namely TKDP), including the internal 1) context knowledge and the external 2) label knowledge & 3) sememe knowledge. TKDP encodes the three feature sources and incorporates them into the soft prompt embeddings, which are further injected into an existing pre-trained language model to facilitate predictions. On five benchmark datasets, our knowledge-enriched model boosts by at most 11.53% F1 over the raw deep prompt method, and significantly outperforms 8 strong-performing baseline systems in 5-/10-/20-shot settings, showing great potential in few-shot NER. Our TKDP can be broadly adapted to other few-shot tasks without effort.

JGAT: a joint spatio-temporal graph attention model for brain decoding

The decoding of brain neural networks has been an intriguing topic in neuroscience for a well-rounded understanding of different types of brain disorders and cognitive stimuli. Integrating different types of connectivity, e.g., Functional Connectivity (FC) and Structural Connectivity (SC), from multi-modal imaging techniques can take their complementary information into account and therefore have the potential to get better decoding capability. However, traditional approaches for integrating FC and SC overlook the dynamical variations, which stand a great chance to over-generalize the brain neural network. In this paper, we propose a Joint kernel Graph Attention Network (JGAT), which is a new multi-modal temporal graph attention network framework. It integrates the data from functional Magnetic Resonance Images (fMRI) and Diffusion Weighted Imaging (DWI) while preserving the dynamic information at the same time. We conduct brain-decoding tasks with our JGAT on four independent datasets: three of 7T fMRI datasets from the Human Connectome Project (HCP) and one from animal neural recordings. Furthermore, with Attention Scores (AS) and Frame Scores (FS) computed and learned from the model, we can locate several informative temporal segments and build meaningful dynamical pathways along the temporal domain for the HCP datasets. The URL to the code of JGAT model: https://github.com/BRAINML-GT/JGAT.

Beyond One-Model-Fits-All: A Survey of Domain Specialization for Large Language Models

Large language models (LLMs) have significantly advanced the field of natural language processing (NLP), providing a highly useful, task-agnostic foundation for a wide range of applications. The great promise of LLMs as general task solvers motivated people to extend their functionality largely beyond just a ``chatbot'', and use it as an assistant or even replacement for domain experts and tools in specific domains such as healthcare, finance, and education. However, directly applying LLMs to solve sophisticated problems in specific domains meets many hurdles, caused by the heterogeneity of domain data, the sophistication of domain knowledge, the uniqueness of domain objectives, and the diversity of the constraints (e.g., various social norms, cultural conformity, religious beliefs, and ethical standards in the domain applications). To fill such a gap, explosively-increase research, and practices have been conducted in very recent years on the domain specialization of LLMs, which, however, calls for a comprehensive and systematic review to better summarizes and guide this promising domain. In this survey paper, first, we propose a systematic taxonomy that categorizes the LLM domain-specialization techniques based on the accessibility to LLMs and summarizes the framework for all the subcategories as well as their relations and differences to each other. We also present a comprehensive taxonomy of critical application domains that can benefit from specialized LLMs, discussing their practical significance and open challenges. Furthermore, we offer insights into the current research status and future trends in this area.