MPIC: Position-Independent Multimodal Context Caching System for Efficient MLLM Serving

The context caching technique is employed to accelerate the Multimodal Large Language Model (MLLM) inference by prevailing serving platforms currently. However, this approach merely reuses the Key-Value (KV) cache of the initial sequence of prompt, resulting in full KV cache recomputation even if the prefix differs slightly. This becomes particularly inefficient in the context of interleaved text and images, as well as multimodal retrieval-augmented generation. This paper proposes position-independent caching as a more effective approach for multimodal information management. We have designed and implemented a caching system, named MPIC, to address both system-level and algorithm-level challenges. MPIC stores the KV cache on local or remote disks when receiving multimodal data, and calculates and loads the KV cache in parallel during inference. To mitigate accuracy degradation, we have incorporated integrated reuse and recompute mechanisms within the system. The experimental results demonstrate that MPIC can achieve up to 54% reduction in response time compared to existing context caching systems, while maintaining negligible or no accuracy loss.

EPIC: Efficient Position-Independent Context Caching for Serving Large Language Models

Large Language Models (LLMs) are critical for a wide range of applications, but serving them efficiently becomes increasingly challenging as inputs become more complex. Context caching improves serving performance by exploiting inter-request dependency and reusing key-value (KV) cache across requests, thus improving time-to-first-token (TTFT). However, existing prefix-based context caching requires exact token prefix matches, limiting cache reuse in few-shot learning, multi-document QA, or retrieval-augmented generation, where prefixes may vary. In this paper, we present EPIC, an LLM serving system that introduces position-independent context caching (PIC), enabling modular KV cache reuse regardless of token chunk position (or prefix). EPIC features two key designs: AttnLink, which leverages static attention sparsity to minimize recomputation for accuracy recovery, and KVSplit, a customizable chunking method that preserves semantic coherence. Our experiments demonstrate that Epic delivers up to 8x improvements in TTFT and 7x throughput over existing systems, with negligible or no accuracy loss. By addressing the limitations of traditional caching approaches, Epic enables more scalable and efficient LLM inference.

A Plug-and-Play Image Registration Network

Deformable image registration (DIR) is an active research topic in biomedical imaging. There is a growing interest in developing DIR methods based on deep learning (DL). A traditional DL approach to DIR is based on training a convolutional neural network (CNN) to estimate the registration field between two input images. While conceptually simple, this approach comes with a limitation that it exclusively relies on a pre-trained CNN without explicitly enforcing fidelity between the registered image and the reference. We present plug-and-play image registration network (PIRATE) as a new DIR method that addresses this issue by integrating an explicit data-fidelity penalty and a CNN prior. PIRATE pre-trains a CNN denoiser on the registration field and "plugs" it into an iterative method as a regularizer. We additionally present PIRATE+ that fine-tunes the CNN prior in PIRATE using deep equilibrium models (DEQ). PIRATE+ interprets the fixed-point iteration of PIRATE as a network with effectively infinite layers and then trains the resulting network end-to-end, enabling it to learn more task-specific information and boosting its performance. Our numerical results on OASIS and CANDI datasets show that our methods achieve state-of-the-art performance on DIR.

Robustness of Deep Equilibrium Architectures to Changes in the Measurement Model

Deep model-based architectures (DMBAs) are widely used in imaging inverse problems to integrate physical measurement models and learned image priors. Plug-and-play priors (PnP) and deep equilibrium models (DEQ) are two DMBA frameworks that have received significant attention. The key difference between the two is that the image prior in DEQ is trained by using a specific measurement model, while that in PnP is trained as a general image denoiser. This difference is behind a common assumption that PnP is more robust to changes in the measurement models compared to DEQ. This paper investigates the robustness of DEQ priors to changes in the measurement models. Our results on two imaging inverse problems suggest that DEQ priors trained under mismatched measurement models outperform image denoisers.