Multi-modality transrectal ultrasound video classification for identification of clinically significant prostate cancer

Prostate cancer is the most common noncutaneous cancer in the world. Recently, multi-modality transrectal ultrasound (TRUS) has increasingly become an effective tool for the guidance of prostate biopsies. With the aim of effectively identifying prostate cancer, we propose a framework for the classification of clinically significant prostate cancer (csPCa) from multi-modality TRUS videos. The framework utilizes two 3D ResNet-50 models to extract features from B-mode images and shear wave elastography images, respectively. An adaptive spatial fusion module is introduced to aggregate two modalities' features. An orthogonal regularized loss is further used to mitigate feature redundancy. The proposed framework is evaluated on an in-house dataset containing 512 TRUS videos, and achieves favorable performance in identifying csPCa with an area under curve (AUC) of 0.84. Furthermore, the visualized class activation mapping (CAM) images generated from the proposed framework may provide valuable guidance for the localization of csPCa, thus facilitating the TRUS-guided targeted biopsy. Our code is publicly available at https://github.com/2313595986/ProstateTRUS.

Multi-modality transrectal ultrasound vudei classification for identification of clinically significant prostate cancer

Prostate cancer is the most common noncutaneous cancer in the world. Recently, multi-modality transrectal ultrasound (TRUS) has increasingly become an effective tool for the guidance of prostate biopsies. With the aim of effectively identifying prostate cancer, we propose a framework for the classification of clinically significant prostate cancer (csPCa) from multi-modality TRUS videos. The framework utilizes two 3D ResNet-50 models to extract features from B-mode images and shear wave elastography images, respectively. An adaptive spatial fusion module is introduced to aggregate two modalities' features. An orthogonal regularized loss is further used to mitigate feature redundancy. The proposed framework is evaluated on an in-house dataset containing 512 TRUS videos, and achieves favorable performance in identifying csPCa with an area under curve (AUC) of 0.84. Furthermore, the visualized class activation mapping (CAM) images generated from the proposed framework may provide valuable guidance for the localization of csPCa, thus facilitating the TRUS-guided targeted biopsy. Our code is publicly available at https://github.com/2313595986/ProstateTRUS.

AI-Generated Content Enhanced Computer-Aided Diagnosis Model for Thyroid Nodules: A ChatGPT-Style Assistant

An artificial intelligence-generated content-enhanced computer-aided diagnosis (AIGC-CAD) model, designated as ThyGPT, has been developed. This model, inspired by the architecture of ChatGPT, could assist radiologists in assessing the risk of thyroid nodules through semantic-level human-machine interaction. A dataset comprising 19,165 thyroid nodule ultrasound cases from Zhejiang Cancer Hospital was assembled to facilitate the training and validation of the model. After training, ThyGPT could automatically evaluate thyroid nodule and engage in effective communication with physicians through human-computer interaction. The performance of ThyGPT was rigorously quantified using established metrics such as the receiver operating characteristic (ROC) curve, area under the curve (AUC), sensitivity, and specificity. The empirical findings revealed that radiologists, when supplemented with ThyGPT, markedly surpassed the diagnostic acumen of their peers utilizing traditional methods as well as the performance of the model in isolation. These findings suggest that AIGC-CAD systems, exemplified by ThyGPT, hold the promise to fundamentally transform the diagnostic workflows of radiologists in forthcoming years.