ManiPose: Manifold-Constrained Multi-Hypothesis 3D Human Pose Estimation

Monocular 3D human pose estimation (3D-HPE) is an inherently ambiguous task, as a 2D pose in an image might originate from different possible 3D poses. Yet, most 3D-HPE methods rely on regression models, which assume a one-to-one mapping between inputs and outputs. In this work, we provide theoretical and empirical evidence that, because of this ambiguity, common regression models are bound to predict topologically inconsistent poses, and that traditional evaluation metrics, such as the MPJPE, P-MPJPE and PCK, are insufficient to assess this aspect. As a solution, we propose ManiPose, a novel manifold-constrained multi-hypothesis model capable of proposing multiple candidate 3D poses for each 2D input, together with their corresponding plausibility. Unlike previous multi-hypothesis approaches, our solution is completely supervised and does not rely on complex generative models, thus greatly facilitating its training and usage. Furthermore, by constraining our model to lie within the human pose manifold, we can guarantee the consistency of all hypothetical poses predicted with our approach, which was not possible in previous works. We illustrate the usefulness of ManiPose in a synthetic 1D-to-2D lifting setting and demonstrate on real-world datasets that it outperforms state-of-the-art models in pose consistency by a large margin, while still reaching competitive MPJPE performance.

DiffHPE: Robust, Coherent 3D Human Pose Lifting with Diffusion

We present an innovative approach to 3D Human Pose Estimation (3D-HPE) by integrating cutting-edge diffusion models, which have revolutionized diverse fields, but are relatively unexplored in 3D-HPE. We show that diffusion models enhance the accuracy, robustness, and coherence of human pose estimations. We introduce DiffHPE, a novel strategy for harnessing diffusion models in 3D-HPE, and demonstrate its ability to refine standard supervised 3D-HPE. We also show how diffusion models lead to more robust estimations in the face of occlusions, and improve the time-coherence and the sagittal symmetry of predictions. Using the Human\,3.6M dataset, we illustrate the effectiveness of our approach and its superiority over existing models, even under adverse situations where the occlusion patterns in training do not match those in inference. Our findings indicate that while standalone diffusion models provide commendable performance, their accuracy is even better in combination with supervised models, opening exciting new avenues for 3D-HPE research.

The Performance of Transferability Metrics does not Translate to Medical Tasks

Transfer learning boosts the performance of medical image analysis by enabling deep learning (DL) on small datasets through the knowledge acquired from large ones. As the number of DL architectures explodes, exhaustively attempting all candidates becomes unfeasible, motivating cheaper alternatives for choosing them. Transferability scoring methods emerge as an enticing solution, allowing to efficiently calculate a score that correlates with the architecture accuracy on any target dataset. However, since transferability scores have not been evaluated on medical datasets, their use in this context remains uncertain, preventing them from benefiting practitioners. We fill that gap in this work, thoroughly evaluating seven transferability scores in three medical applications, including out-of-distribution scenarios. Despite promising results in general-purpose datasets, our results show that no transferability score can reliably and consistently estimate target performance in medical contexts, inviting further work in that direction.

Test-Time Selection for Robust Skin Lesion Analysis

Skin lesion analysis models are biased by artifacts placed during image acquisition, which influence model predictions despite carrying no clinical information. Solutions that address this problem by regularizing models to prevent learning those spurious features achieve only partial success, and existing test-time debiasing techniques are inappropriate for skin lesion analysis due to either making unrealistic assumptions on the distribution of test data or requiring laborious annotation from medical practitioners. We propose TTS (Test-Time Selection), a human-in-the-loop method that leverages positive (e.g., lesion area) and negative (e.g., artifacts) keypoints in test samples. TTS effectively steers models away from exploiting spurious artifact-related correlations without retraining, and with less annotation requirements. Our solution is robust to a varying availability of annotations, and different levels of bias. We showcase on the ISIC2019 dataset (for which we release a subset of annotated images) how our model could be deployed in the real-world for mitigating bias.

Slimmable Encoders for Flexible Split DNNs in Bandwidth and Resource Constrained IoT Systems

The execution of large deep neural networks (DNN) at mobile edge devices requires considerable consumption of critical resources, such as energy, while imposing demands on hardware capabilities. In approaches based on edge computing the execution of the models is offloaded to a compute-capable device positioned at the edge of 5G infrastructures. The main issue of the latter class of approaches is the need to transport information-rich signals over wireless links with limited and time-varying capacity. The recent split computing paradigm attempts to resolve this impasse by distributing the execution of DNN models across the layers of the systems to reduce the amount of data to be transmitted while imposing minimal computing load on mobile devices. In this context, we propose a novel split computing approach based on slimmable ensemble encoders. The key advantage of our design is the ability to adapt computational load and transmitted data size in real-time with minimal overhead and time. This is in contrast with existing approaches, where the same adaptation requires costly context switching and model loading. Moreover, our model outperforms existing solutions in terms of compression efficacy and execution time, especially in the context of weak mobile devices. We present a comprehensive comparison with the most advanced split computing solutions, as well as an experimental evaluation on GPU-less devices.

Even Small Correlation and Diversity Shifts Pose Dataset-Bias Issues

Distribution shifts are common in real-world datasets and can affect the performance and reliability of deep learning models. In this paper, we study two types of distribution shifts: diversity shifts, which occur when test samples exhibit patterns unseen during training, and correlation shifts, which occur when test data present a different correlation between seen invariant and spurious features. We propose an integrated protocol to analyze both types of shifts using datasets where they co-exist in a controllable manner. Finally, we apply our approach to a real-world classification problem of skin cancer analysis, using out-of-distribution datasets and specialized bias annotations. Our protocol reveals three findings: 1) Models learn and propagate correlation shifts even with low-bias training; this poses a risk of accumulating and combining unaccountable weak biases; 2) Models learn robust features in high- and low-bias scenarios but use spurious ones if test samples have them; this suggests that spurious correlations do not impair the learning of robust features; 3) Diversity shift can reduce the reliance on spurious correlations; this is counter intuitive since we expect biased models to depend more on biases when invariant features are missing. Our work has implications for distribution shift research and practice, providing new insights into how models learn and rely on spurious correlations under different types of shifts.

Artifact-Based Domain Generalization of Skin Lesion Models

Deep Learning failure cases are abundant, particularly in the medical area. Recent studies in out-of-distribution generalization have advanced considerably on well-controlled synthetic datasets, but they do not represent medical imaging contexts. We propose a pipeline that relies on artifacts annotation to enable generalization evaluation and debiasing for the challenging skin lesion analysis context. First, we partition the data into levels of increasingly higher biased training and test sets for better generalization assessment. Then, we create environments based on skin lesion artifacts to enable domain generalization methods. Finally, after robust training, we perform a test-time debiasing procedure, reducing spurious features in inference images. Our experiments show our pipeline improves performance metrics in biased cases, and avoids artifacts when using explanation methods. Still, when evaluating such models in out-of-distribution data, they did not prefer clinically-meaningful features. Instead, performance only improved in test sets that present similar artifacts from training, suggesting models learned to ignore the known set of artifacts. Our results raise a concern that debiasing models towards a single aspect may not be enough for fair skin lesion analysis.

A Survey on Deep Learning for Skin Lesion Segmentation

Skin cancer is a major public health problem that could benefit from computer-aided diagnosis to reduce the burden of this common disease. Skin lesion segmentation from images is an important step toward achieving this goal. However, the presence of natural and artificial artifacts (e.g., hair and air bubbles), intrinsic factors (e.g., lesion shape and contrast), and variations in image acquisition conditions make skin lesion segmentation a challenging task. Recently, various researchers have explored the applicability of deep learning models to skin lesion segmentation. In this survey, we cross-examine 134 research papers that deal with deep learning based segmentation of skin lesions. We analyze these works along several dimensions, including input data (datasets, preprocessing, and synthetic data generation), model design (architecture, modules, and losses), and evaluation aspects (data annotation requirements and segmentation performance). We discuss these dimensions both from the viewpoint of select seminal works, and from a systematic viewpoint, examining how those choices have influenced current trends, and how their limitations should be addressed. We summarize all examined works in a comprehensive table to facilitate comparisons.

An Evaluation of Self-Supervised Pre-Training for Skin-Lesion Analysis

Self-supervised pre-training appears as an advantageous alternative to supervised pre-trained for transfer learning. By synthesizing annotations on pretext tasks, self-supervision allows to pre-train models on large amounts of pseudo-labels before fine-tuning them on the target task. In this work, we assess self-supervision for the diagnosis of skin lesions, comparing three self-supervised pipelines to a challenging supervised baseline, on five test datasets comprising in- and out-of-distribution samples. Our results show that self-supervision is competitive both in improving accuracies and in reducing the variability of outcomes. Self-supervision proves particularly useful for low training data scenarios ($<1\,500$ and $<150$ samples), where its ability to stabilize the outcomes is essential to provide sound results.