DeFeeNet: Consecutive 3D Human Motion Prediction with Deviation Feedback

Let us rethink the real-world scenarios that require human motion prediction techniques, such as human-robot collaboration. Current works simplify the task of predicting human motions into a one-off process of forecasting a short future sequence (usually no longer than 1 second) based on a historical observed one. However, such simplification may fail to meet practical needs due to the neglect of the fact that motion prediction in real applications is not an isolated ``observe then predict'' unit, but a consecutive process composed of many rounds of such unit, semi-overlapped along the entire sequence. As time goes on, the predicted part of previous round has its corresponding ground truth observable in the new round, but their deviation in-between is neither exploited nor able to be captured by existing isolated learning fashion. In this paper, we propose DeFeeNet, a simple yet effective network that can be added on existing one-off prediction models to realize deviation perception and feedback when applied to consecutive motion prediction task. At each prediction round, the deviation generated by previous unit is first encoded by our DeFeeNet, and then incorporated into the existing predictor to enable a deviation-aware prediction manner, which, for the first time, allows for information transmit across adjacent prediction units. We design two versions of DeFeeNet as MLP-based and GRU-based, respectively. On Human3.6M and more complicated BABEL, experimental results indicate that our proposed network improves consecutive human motion prediction performance regardless of the basic model.

M3AE: Multimodal Representation Learning for Brain Tumor Segmentation with Missing Modalities

Multimodal magnetic resonance imaging (MRI) provides complementary information for sub-region analysis of brain tumors. Plenty of methods have been proposed for automatic brain tumor segmentation using four common MRI modalities and achieved remarkable performance. In practice, however, it is common to have one or more modalities missing due to image corruption, artifacts, acquisition protocols, allergy to contrast agents, or simply cost. In this work, we propose a novel two-stage framework for brain tumor segmentation with missing modalities. In the first stage, a multimodal masked autoencoder (M3AE) is proposed, where both random modalities (i.e., modality dropout) and random patches of the remaining modalities are masked for a reconstruction task, for self-supervised learning of robust multimodal representations against missing modalities. To this end, we name our framework M3AE. Meanwhile, we employ model inversion to optimize a representative full-modal image at marginal extra cost, which will be used to substitute for the missing modalities and boost performance during inference. Then in the second stage, a memory-efficient self distillation is proposed to distill knowledge between heterogenous missing-modal situations while fine-tuning the model for supervised segmentation. Our M3AE belongs to the 'catch-all' genre where a single model can be applied to all possible subsets of modalities, thus is economic for both training and deployment. Extensive experiments on BraTS 2018 and 2020 datasets demonstrate its superior performance to existing state-of-the-art methods with missing modalities, as well as the efficacy of its components. Our code is available at: https://github.com/ccarliu/m3ae.

RECIST Weakly Supervised Lesion Segmentation via Label-Space Co-Training

As an essential indicator for cancer progression and treatment response, tumor size is often measured following the response evaluation criteria in solid tumors (RECIST) guideline in CT slices. By marking each lesion with its longest axis and the longest perpendicular one, laborious pixel-wise manual annotation can be avoided. However, such a coarse substitute cannot provide a rich and accurate base to allow versatile quantitative analysis of lesions. To this end, we propose a novel weakly supervised framework to exploit the existing rich RECIST annotations for pixel-wise lesion segmentation. Specifically, a pair of under- and over-segmenting masks are constructed for each lesion based on its RECIST annotation and served as the label for co-training a pair of subnets, respectively, along with the proposed label-space perturbation induced consistency loss to bridge the gap between the two subnets and enable effective co-training. Extensive experiments are conducted on a public dataset to demonstrate the superiority of the proposed framework regarding the RECIST-based weakly supervised segmentation task and its universal applicability to various backbone networks.

MADAv2: Advanced Multi-Anchor Based Active Domain Adaptation Segmentation

Unsupervised domain adaption has been widely adopted in tasks with scarce annotated data. Unfortunately, mapping the target-domain distribution to the source-domain unconditionally may distort the essential structural information of the target-domain data, leading to inferior performance. To address this issue, we firstly propose to introduce active sample selection to assist domain adaptation regarding the semantic segmentation task. By innovatively adopting multiple anchors instead of a single centroid, both source and target domains can be better characterized as multimodal distributions, in which way more complementary and informative samples are selected from the target domain. With only a little workload to manually annotate these active samples, the distortion of the target-domain distribution can be effectively alleviated, achieving a large performance gain. In addition, a powerful semi-supervised domain adaptation strategy is proposed to alleviate the long-tail distribution problem and further improve the segmentation performance. Extensive experiments are conducted on public datasets, and the results demonstrate that the proposed approach outperforms state-of-the-art methods by large margins and achieves similar performance to the fully-supervised upperbound, i.e., 71.4% mIoU on GTA5 and 71.8% mIoU on SYNTHIA. The effectiveness of each component is also verified by thorough ablation studies.

Lesion Guided Explainable Few Weak-shot Medical Report Generation

Medical images are widely used in clinical practice for diagnosis. Automatically generating interpretable medical reports can reduce radiologists' burden and facilitate timely care. However, most existing approaches to automatic report generation require sufficient labeled data for training. In addition, the learned model can only generate reports for the training classes, lacking the ability to adapt to previously unseen novel diseases. To this end, we propose a lesion guided explainable few weak-shot medical report generation framework that learns correlation between seen and novel classes through visual and semantic feature alignment, aiming to generate medical reports for diseases not observed in training. It integrates a lesion-centric feature extractor and a Transformer-based report generation module. Concretely, the lesion-centric feature extractor detects the abnormal regions and learns correlations between seen and novel classes with multi-view (visual and lexical) embeddings. Then, features of the detected regions and corresponding embeddings are concatenated as multi-view input to the report generation module for explainable report generation, including text descriptions and corresponding abnormal regions detected in the images. We conduct experiments on FFA-IR, a dataset providing explainable annotations, showing that our framework outperforms others on report generation for novel diseases.

Human Joint Kinematics Diffusion-Refinement for Stochastic Motion Prediction

Stochastic human motion prediction aims to forecast multiple plausible future motions given a single pose sequence from the past. Most previous works focus on designing elaborate losses to improve the accuracy, while the diversity is typically characterized by randomly sampling a set of latent variables from the latent prior, which is then decoded into possible motions. This joint training of sampling and decoding, however, suffers from posterior collapse as the learned latent variables tend to be ignored by a strong decoder, leading to limited diversity. Alternatively, inspired by the diffusion process in nonequilibrium thermodynamics, we propose MotionDiff, a diffusion probabilistic model to treat the kinematics of human joints as heated particles, which will diffuse from original states to a noise distribution. This process offers a natural way to obtain the "whitened" latents without any trainable parameters, and human motion prediction can be regarded as the reverse diffusion process that converts the noise distribution into realistic future motions conditioned on the observed sequence. Specifically, MotionDiff consists of two parts: a spatial-temporal transformer-based diffusion network to generate diverse yet plausible motions, and a graph convolutional network to further refine the outputs. Experimental results on two datasets demonstrate that our model yields the competitive performance in terms of both accuracy and diversity.

A Benchmark for Weakly Semi-Supervised Abnormality Localization in Chest X-Rays

Accurate abnormality localization in chest X-rays (CXR) can benefit the clinical diagnosis of various thoracic diseases. However, the lesion-level annotation can only be performed by experienced radiologists, and it is tedious and time-consuming, thus difficult to acquire. Such a situation results in a difficulty to develop a fully-supervised abnormality localization system for CXR. In this regard, we propose to train the CXR abnormality localization framework via a weakly semi-supervised strategy, termed Point Beyond Class (PBC), which utilizes a small number of fully annotated CXRs with lesion-level bounding boxes and extensive weakly annotated samples by points. Such a point annotation setting can provide weakly instance-level information for abnormality localization with a marginal annotation cost. Particularly, the core idea behind our PBC is to learn a robust and accurate mapping from the point annotations to the bounding boxes against the variance of annotated points. To achieve that, a regularization term, namely multi-point consistency, is proposed, which drives the model to generate the consistent bounding box from different point annotations inside the same abnormality. Furthermore, a self-supervision, termed symmetric consistency, is also proposed to deeply exploit the useful information from the weakly annotated data for abnormality localization. Experimental results on RSNA and VinDr-CXR datasets justify the effectiveness of the proposed method. When less than 20% box-level labels are used for training, an improvement of ~5 in mAP can be achieved by our PBC, compared to the current state-of-the-art method (i.e., Point DETR). Code is available at https://github.com/HaozheLiu-ST/Point-Beyond-Class.

Dense Cross-Query-and-Support Attention Weighted Mask Aggregation for Few-Shot Segmentation

Research into Few-shot Semantic Segmentation (FSS) has attracted great attention, with the goal to segment target objects in a query image given only a few annotated support images of the target class. A key to this challenging task is to fully utilize the information in the support images by exploiting fine-grained correlations between the query and support images. However, most existing approaches either compressed the support information into a few class-wise prototypes, or used partial support information (e.g., only foreground) at the pixel level, causing non-negligible information loss. In this paper, we propose Dense pixel-wise Cross-query-and-support Attention weighted Mask Aggregation (DCAMA), where both foreground and background support information are fully exploited via multi-level pixel-wise correlations between paired query and support features. Implemented with the scaled dot-product attention in the Transformer architecture, DCAMA treats every query pixel as a token, computes its similarities with all support pixels, and predicts its segmentation label as an additive aggregation of all the support pixels' labels -- weighted by the similarities. Based on the unique formulation of DCAMA, we further propose efficient and effective one-pass inference for n-shot segmentation, where pixels of all support images are collected for the mask aggregation at once. Experiments show that our DCAMA significantly advances the state of the art on standard FSS benchmarks of PASCAL-5i, COCO-20i, and FSS-1000, e.g., with 3.1%, 9.7%, and 3.6% absolute improvements in 1-shot mIoU over previous best records. Ablative studies also verify the design DCAMA.

Deformer: Towards Displacement Field Learning for Unsupervised Medical Image Registration

Recently, deep-learning-based approaches have been widely studied for deformable image registration task. However, most efforts directly map the composite image representation to spatial transformation through the convolutional neural network, ignoring its limited ability to capture spatial correspondence. On the other hand, Transformer can better characterize the spatial relationship with attention mechanism, its long-range dependency may be harmful to the registration task, where voxels with too large distances are unlikely to be corresponding pairs. In this study, we propose a novel Deformer module along with a multi-scale framework for the deformable image registration task. The Deformer module is designed to facilitate the mapping from image representation to spatial transformation by formulating the displacement vector prediction as the weighted summation of several bases. With the multi-scale framework to predict the displacement fields in a coarse-to-fine manner, superior performance can be achieved compared with traditional and learning-based approaches. Comprehensive experiments on two public datasets are conducted to demonstrate the effectiveness of the proposed Deformer module as well as the multi-scale framework.