Recently, diffusion models have gained significant attention as a novel set of deep learning-based generative methods. These models attempt to sample data from a Gaussian distribution that adheres to a target distribution, and have been successfully adapted to the reconstruction of MRI data. However, as an unconditional generative model, the diffusion model typically disrupts image coordination because of the consistent projection of data introduced by conditional bootstrap. This often results in image fragmentation and incoherence. Furthermore, the inherent limitations of the diffusion model often lead to excessive smoothing of the generated images. In the same vein, some deep learning-based models often suffer from poor generalization performance, meaning their effectiveness is greatly affected by different acceleration factors. To address these challenges, we propose a novel diffusion model-based MRI reconstruction method, named TC-DiffRecon, which does not rely on a specific acceleration factor for training. We also suggest the incorporation of the MF-UNet module, designed to enhance the quality of MRI images generated by the model while mitigating the over-smoothing issue to a certain extent. During the image generation sampling process, we employ a novel TCKG module and a Coarse-to-Fine sampling scheme. These additions aim to harmonize image texture, expedite the sampling process, while achieving data consistency. Our source code is available at https://github.com/JustlfC03/TC-DiffRecon.
Traditional supervised learning methods have historically encountered certain constraints in medical image segmentation due to the challenging collection process, high labeling cost, low signal-to-noise ratio, and complex features characterizing biomedical images. This paper proposes a semi-supervised model, DFCPS, which innovatively incorporates the Fixmatch concept. This significantly enhances the model's performance and generalizability through data augmentation processing, employing varied strategies for unlabeled data. Concurrently, the model design gives appropriate emphasis to the generation, filtration, and refinement processes of pseudo-labels. The novel concept of cross-pseudo-supervision is introduced, integrating consistency learning with self-training. This enables the model to fully leverage pseudo-labels from multiple perspectives, thereby enhancing training diversity. The DFCPS model is compared with both baseline and advanced models using the publicly accessible Kvasir-SEG dataset. Across all four subdivisions containing different proportions of unlabeled data, our model consistently exhibits superior performance. Our source code is available at https://github.com/JustlfC03/DFCPS.
In standard hospital blood tests, the traditional process requires doctors to manually isolate leukocytes from microscopic images of patients' blood using microscopes. These isolated leukocytes are then categorized via automatic leukocyte classifiers to determine the proportion and volume of different types of leukocytes present in the blood samples, aiding disease diagnosis. This methodology is not only time-consuming and labor-intensive, but it also has a high propensity for errors due to factors such as image quality and environmental conditions, which could potentially lead to incorrect subsequent classifications and misdiagnosis. To address these issues, this paper proposes an innovative method of leukocyte detection: the Multi-level Feature Fusion and Deformable Self-attention DETR (MFDS-DETR). To tackle the issue of leukocyte scale disparity, we designed the High-level Screening-feature Fusion Pyramid (HS-FPN), enabling multi-level fusion. This model uses high-level features as weights to filter low-level feature information via a channel attention module and then merges the screened information with the high-level features, thus enhancing the model's feature expression capability. Further, we address the issue of leukocyte feature scarcity by incorporating a multi-scale deformable self-attention module in the encoder and using the self-attention and cross-deformable attention mechanisms in the decoder, which aids in the extraction of the global features of the leukocyte feature maps. The effectiveness, superiority, and generalizability of the proposed MFDS-DETR method are confirmed through comparisons with other cutting-edge leukocyte detection models using the private WBCDD, public LISC and BCCD datasets. Our source code and private WBCCD dataset are available at https://github.com/JustlfC03/MFDS-DETR.