Do Pathology Vision-Language Models Truly See Pathology?

Pathology vision-language models (VLMs) have recently progressed rapidly and are commonly evaluated by answer accuracy on pathology VQA benchmarks. However, we dig into current evaluations and identify three overlooked issues: 1) Visual evidence is not always necessary. For instance, Gemini-3-Pro achieves 53.5% average accuracy across 5 VQA benchmarks without any visual input. 2) Domain training can improve accuracy without proportional gains in visual binding. Compared with Qwen2.5-VL-7B, Patho-R1-7B exhibits a 5.8-point lower multimodal gain and a 3.7-point lower attention IoU. 3) Entity-level attention is diffuse and weakly query-specific. On PathVG, attention maps remain highly correlated across different entity queries. These issues can lead to substantial misjudgments of pathology VLMs' actual multimodal capabilities. To this end, we present PathBind, a benchmark comprising 2,600 samples: PathBind-VQA with 1,500 questions across six dimensions, PathBind-PTA with 600 questions from a private pathology teaching atlas, and PathBind-Grounding with 500 expert-curated region-level samples. Each component undergoes task-specific automated filtering and expert review to reduce textual shortcuts and improve entity-region correspondence. We evaluate 18 representative VLMs on VQA samples of PathBind and five existing pathology VQA benchmarks, and further evaluate 10 VLMs on PathBind-Grounding and PathVG. Results show that current pathology VLMs still exhibit a substantial gap between answer-side performance and visual-semantic binding.

HieDG: A Hierarchical Discrete Geometry-Guided Framework for Multi-Animal Tracking

Multi-animal tracking (MAT) is critical for wildlife monitoring and behavioral analysis, yet remains challenging due to uniform appearance, high density, and irregular motion. Existing methods typically follow heuristic- or query-based paradigms: the former relies on handcrafted geometric associations without end-to-end optimization, whereas the latter enables joint optimization but relies heavily on appearance embeddings. In such conditions, continuous geometric embeddings can be unstable, as small coordinate perturbations may disproportionately alter cross-frame attention weights, degrading identity association performance. To address this limitation, we propose HieDG, a Hierarchical Discrete Geometry-guided tracking framework that reformulates geometric dynamics as structured discrete representations within a query-based tracker. Instead of directly using raw geometric signals, HieDG employs a two-stage residual codebook to discretize position, scale, and velocity cues, transforming unstable continuous geometry into structured, stable discrete tokens. These tokens are aligned with visual embeddings and integrated into the tracking queries to enhance identity consistency. Extensive experiments on animal-specific benchmarks (AnimalTrack, BFT, and BuckTales) demonstrate state-of-the-art association performance with significant improvements in HOTA, AssA, and IDF1. Additional evaluations on generic multi-object tracking benchmarks, including DanceTrack and SportsMOT, show competitive performance, indicating the broader applicability of discretized geometric modeling beyond animal-specific scenarios.

SkelEM: Training-Signal Decoupling of Skeleton and Diffusion for Self-supervised Axial Super-Resolution in Volume Microscopy

Volume microscopy, including electron and light microscopy, suffers from severe anisotropic resolution due to physical axial sectioning. Existing self-supervised axial super-resolution (ASR) methods face a trilemma bounded by overly smoothed regression textures, structural hallucinations of pure diffusion models, and prohibitive inference latency. In this paper, we propose Skeleton-refinE Microscopy (SkelEM), a self-supervised framework that decouples ASR at the training-signal level: a frozen topological network and a diffusion refiner are optimized by disjoint objectives, separating low-frequency topology formulation from high-frequency detail enhancement. Building on this deterministic skeleton, we exploit a unified cycle-consistent mechanism on input sparse slices to simultaneously extract a real-domain residual prior and bidirectionally align the diffusion refiner, washing away cross-plane artifacts without synthetic bias. By truncating the reverse diffusion process with this physical prior, SkelEM achieves high-fidelity detail restoration in merely $\le 5$ steps. To rigorously assess cross-instrument generalization, we further introduce BRAVE-ASR, a new benchmark of co-aligned anisotropic and isotropic volumes acquired on a Plasma-FIB instrument. Across public benchmarks, SkelEM achieves the most favorable balance across the fidelity-perception trade-off among self-supervised methods, with state-of-the-art downstream membrane segmentation performance and robust zero-shot generalization across distinct modalities.