Evidence-Grounded AI for Musculoskeletal Care

Musculoskeletal diseases are among the leading causes of disability worldwide and create the greatest global need for rehabilitation. Because recovery, remodelling and degeneration often unfold over months to years, musculoskeletal care requires longitudinal management that repeatedly integrates evolving patient evidence, external medical knowledge and stage-specific functional goals. In routine practice, this evidence is fragmented across visits, departments and hospital systems, limiting individualized, evidence-based care. Here we report OrthoPilot, a clinical artificial intelligence system powered by a large language model that integrates hospital data streams with authoritative external knowledge for continuous musculoskeletal management. OrthoPilot autonomously retrieves real-time imaging, laboratory, pathology and order data and converts evolving patient states into evidence-based decisions from admission diagnosis to rehabilitation planning. We established a specialist-validated benchmark from real-world electronic health records spanning 1,000 disease codes. In a reader study across the complete care pathway, OrthoPilot was compared with 81 orthopaedic physicians and surpassed experts with 25 years of experience in diagnostic reasoning, clinical decision-making and management planning. It also outperformed all evaluated intelligent systems across 60 external clinical centres. In a prospective study of 1,870 complex cases, OrthoPilot increased full-chain management success by 10.6%. During an 8-month randomised deployment involving 8,240 inpatients, it increased cumulative cases per bed by 9.7% and improved patient-reported access to health information. These results move clinical AI from predicting isolated events toward executing longitudinal management across complete musculoskeletal care pathways.

LoViF 2026 Challenge on Human-oriented Semantic Image Quality Assessment: Methods and Results

This paper reviews the LoViF 2026 Challenge on Human-oriented Semantic Image Quality Assessment. This challenge aims to raise a new direction, i.e., how to evaluate the loss of semantic information from the human perspective, intending to promote the development of some new directions, like semantic coding, processing, and semantic-oriented optimization, etc. Unlike existing datasets of quality assessment, we form a dataset of human-oriented semantic quality assessment, termed the SeIQA dataset. This dataset is divided into three parts for this competition: (i) training data: 510 pairs of degraded images and their corresponding ground truth references; (ii) validation data: 80 pairs of degraded images and their corresponding ground-truth references; (iii) testing data: 160 pairs of degraded images and their corresponding ground-truth references. The primary objective of this challenge is to establish a new and powerful benchmark for human-oriented semantic image quality assessment. There are a total of 58 teams registered in this competition, and 6 teams submitted valid solutions and fact sheets for the final testing phase. These submissions achieved state-of-the-art (SOTA) performance on the SeIQA dataset.