Human-AI Collaboration Enables More Empathic Conversations in Text-based Peer-to-Peer Mental Health Support

Advances in artificial intelligence (AI) are enabling systems that augment and collaborate with humans to perform simple, mechanistic tasks like scheduling meetings and grammar-checking text. However, such Human-AI collaboration poses challenges for more complex, creative tasks, such as carrying out empathic conversations, due to difficulties of AI systems in understanding complex human emotions and the open-ended nature of these tasks. Here, we focus on peer-to-peer mental health support, a setting in which empathy is critical for success, and examine how AI can collaborate with humans to facilitate peer empathy during textual, online supportive conversations. We develop Hailey, an AI-in-the-loop agent that provides just-in-time feedback to help participants who provide support (peer supporters) respond more empathically to those seeking help (support seekers). We evaluate Hailey in a non-clinical randomized controlled trial with real-world peer supporters on TalkLife (N=300), a large online peer-to-peer support platform. We show that our Human-AI collaboration approach leads to a 19.60% increase in conversational empathy between peers overall. Furthermore, we find a larger 38.88% increase in empathy within the subsample of peer supporters who self-identify as experiencing difficulty providing support. We systematically analyze the Human-AI collaboration patterns and find that peer supporters are able to use the AI feedback both directly and indirectly without becoming overly reliant on AI while reporting improved self-efficacy post-feedback. Our findings demonstrate the potential of feedback-driven, AI-in-the-loop writing systems to empower humans in open-ended, social, creative tasks such as empathic conversations.

Applications and Techniques for Fast Machine Learning in Science

In this community review report, we discuss applications and techniques for fast machine learning (ML) in science -- the concept of integrating power ML methods into the real-time experimental data processing loop to accelerate scientific discovery. The material for the report builds on two workshops held by the Fast ML for Science community and covers three main areas: applications for fast ML across a number of scientific domains; techniques for training and implementing performant and resource-efficient ML algorithms; and computing architectures, platforms, and technologies for deploying these algorithms. We also present overlapping challenges across the multiple scientific domains where common solutions can be found. This community report is intended to give plenty of examples and inspiration for scientific discovery through integrated and accelerated ML solutions. This is followed by a high-level overview and organization of technical advances, including an abundance of pointers to source material, which can enable these breakthroughs.

Towards Facilitating Empathic Conversations in Online Mental Health Support: A Reinforcement Learning Approach

Online peer-to-peer support platforms enable conversations between millions of people who seek and provide mental health support. If successful, web-based mental health conversations could improve access to treatment and reduce the global disease burden. Psychologists have repeatedly demonstrated that empathy, the ability to understand and feel the emotions and experiences of others, is a key component leading to positive outcomes in supportive conversations. However, recent studies have shown that highly empathic conversations are rare in online mental health platforms. In this paper, we work towards improving empathy in online mental health support conversations. We introduce a new task of empathic rewriting which aims to transform low-empathy conversational posts to higher empathy. Learning such transformations is challenging and requires a deep understanding of empathy while maintaining conversation quality through text fluency and specificity to the conversational context. Here we propose PARTNER, a deep reinforcement learning agent that learns to make sentence-level edits to posts in order to increase the expressed level of empathy while maintaining conversation quality. Our RL agent leverages a policy network, based on a transformer language model adapted from GPT-2, which performs the dual task of generating candidate empathic sentences and adding those sentences at appropriate positions. During training, we reward transformations that increase empathy in posts while maintaining text fluency, context specificity and diversity. Through a combination of automatic and human evaluation, we demonstrate that PARTNER successfully generates more empathic, specific, and diverse responses and outperforms NLP methods from related tasks like style transfer and empathic dialogue generation. Our work has direct implications for facilitating empathic conversations on web-based platforms.

A Computational Approach to Understanding Empathy Expressed in Text-Based Mental Health Support

Empathy is critical to successful mental health support. Empathy measurement has predominantly occurred in synchronous, face-to-face settings, and may not translate to asynchronous, text-based contexts. Because millions of people use text-based platforms for mental health support, understanding empathy in these contexts is crucial. In this work, we present a computational approach to understanding how empathy is expressed in online mental health platforms. We develop a novel unifying theoretically-grounded framework for characterizing the communication of empathy in text-based conversations. We collect and share a corpus of 10k (post, response) pairs annotated using this empathy framework with supporting evidence for annotations (rationales). We develop a multi-task RoBERTa-based bi-encoder model for identifying empathy in conversations and extracting rationales underlying its predictions. Experiments demonstrate that our approach can effectively identify empathic conversations. We further apply this model to analyze 235k mental health interactions and show that users do not self-learn empathy over time, revealing opportunities for empathy training and feedback.

Embedding-based Retrieval in Facebook Search

Search in social networks such as Facebook poses different challenges than in classical web search: besides the query text, it is important to take into account the searcher's context to provide relevant results. Their social graph is an integral part of this context and is a unique aspect of Facebook search. While embedding-based retrieval (EBR) has been applied in eb search engines for years, Facebook search was still mainly based on a Boolean matching model. In this paper, we discuss the techniques for applying EBR to a Facebook Search system. We introduce the unified embedding framework developed to model semantic embeddings for personalized search, and the system to serve embedding-based retrieval in a typical search system based on an inverted index. We discuss various tricks and experiences on end-to-end optimization of the whole system, including ANN parameter tuning and full-stack optimization. Finally, we present our progress on two selected advanced topics about modeling. We evaluated EBR on verticals for Facebook Search with significant metrics gains observed in online A/B experiments. We believe this paper will provide useful insights and experiences to help people on developing embedding-based retrieval systems in search engines.

Developing and Deploying Machine Learning Pipelines against Real-Time Image Streams from the PACS

Executing machine learning (ML) pipelines on radiology images is hard due to limited computing resources in clinical environments, whereas running them in research clusters in real-time requires efficient data transfer capabilities. We propose Niffler, an integrated ML framework that runs in research clusters that receives radiology images in real-time from hospitals' Picture Archiving and Communication Systems (PACS). Niffler consists of an inter-domain data streaming approach that exploits the Digital Imaging and Communications in Medicine (DICOM) protocol to fetch data from the PACS to the data processing servers for executing the ML pipelines. It provides metadata extraction capabilities and Application programming interfaces (APIs) to apply filters on the DICOM images and run the ML pipelines. The outcomes of the ML pipelines can then be shared back with the end-users in a de-identified manner. Evaluations on the Niffler prototype highlight the feasibility and efficiency in running the ML pipelines in real-time from a research cluster on the images received in real-time from hospital PACS.

DeepAISE -- An End-to-End Development and Deployment of a Recurrent Neural Survival Model for Early Prediction of Sepsis

Sepsis, a dysregulated immune system response to infection, is among the leading causes of morbidity, mortality, and cost overruns in the Intensive Care Unit (ICU). Early prediction of sepsis can improve situational awareness amongst clinicians and facilitate timely, protective interventions. While the application of predictive analytics in ICU patients has shown early promising results, much of the work has been encumbered by high false-alarm rates. Efforts to improve specificity have been limited by several factors, most notably the difficulty of labeling sepsis onset time and the low prevalence of septic-events in the ICU. Here, we present DeepAISE (Deep Artificial Intelligence Sepsis Expert), a recurrent neural survival model for the early prediction of sepsis. We show that by coupling a clinical criterion for defining sepsis onset time with a treatment policy (e.g., initiation of antibiotics within one hour of meeting the criterion), one may rank the relative utility of various criteria through offline policy evaluation. Given the optimal criterion, DeepAISE automatically learns predictive features related to higher-order interactions and temporal patterns among clinical risk factors that maximize the data likelihood of observed time to septic events. DeepAISE has been incorporated into a clinical workflow, which provides real-time hourly sepsis risk scores. A comparative study of four baseline models indicates that DeepAISE produces the most accurate predictions (AUC=0.90 and 0.87) and the lowest false alarm rates (FAR=0.20 and 0.26) in two separate cohorts (internal and external, respectively), while simultaneously producing interpretable representations of the clinical time series and risk factors.

Utilizing Automated Breast Cancer Detection to Identify Spatial Distributions of Tumor Infiltrating Lymphocytes in Invasive Breast Cancer

Quantitative assessment of Tumor-TIL spatial relationships is increasingly important in both basic science and clinical aspects of breast cancer research. We have developed and evaluated convolutional neural network (CNN) analysis pipelines to generate combined maps of cancer regions and tumor infiltrating lymphocytes (TILs) in routine diagnostic breast cancer whole slide tissue images (WSIs). We produce interactive whole slide maps that provide 1) insight about the structural patterns and spatial distribution of lymphocytic infiltrates and 2) facilitate improved quantification of TILs. We evaluated both tumor and TIL analyses using three CNN networks - Resnet-34, VGG16 and Inception v4, and demonstrated that the results compared favorably to those obtained by what believe are the best published methods. We have produced open-source tools and generated a public dataset consisting of tumor/TIL maps for 1,015 TCGA breast cancer images. We also present a customized web-based interface that enables easy visualization and interactive exploration of high-resolution combined Tumor-TIL maps for 1,015TCGA invasive breast cancer cases that can be downloaded for further downstream analyses.

Improving Latent User Models in Online Social Media

Modern social platforms are characterized by the presence of rich user-behavior data associated with the publication, sharing and consumption of textual content. Users interact with content and with each other in a complex and dynamic social environment while simultaneously evolving over time. In order to effectively characterize users and predict their future behavior in such a setting, it is necessary to overcome several challenges. Content heterogeneity and temporal inconsistency of behavior data result in severe sparsity at the user level. In this paper, we propose a novel mutual-enhancement framework to simultaneously partition and learn latent activity profiles of users. We propose a flexible user partitioning approach to effectively discover rare behaviors and tackle user-level sparsity. We extensively evaluate the proposed framework on massive datasets from real-world platforms including Q&A networks and interactive online courses (MOOCs). Our results indicate significant gains over state-of-the-art behavior models ( 15% avg ) in a varied range of tasks and our gains are further magnified for users with limited interaction data. The proposed algorithms are amenable to parallelization, scale linearly in the size of datasets, and provide flexibility to model diverse facets of user behavior.