Self-Supervised Foundation Model for Calcium-imaging Population Dynamics

Recent work suggests that large-scale, multi-animal modeling can significantly improve neural recording analysis. However, for functional calcium traces, existing approaches remain task-specific, limiting transfer across common neuroscience objectives. To address this challenge, we propose \textbf{CalM}, a self-supervised neural foundation model trained solely on neuronal calcium traces and adaptable to multiple downstream tasks, including forecasting and decoding. Our key contribution is a pretraining framework, composed of a high-performance tokenizer mapping single-neuron traces into a shared discrete vocabulary, and a dual-axis autoregressive transformer modeling dependencies along both the neural and the temporal axis. We evaluate CalM on a large-scale, multi-animal, multi-session dataset. On the neural population dynamics forecasting task, CalM outperforms strong specialized baselines after pretraining. With a task-specific head, CalM further adapts to the behavior decoding task and achieves superior results compared with supervised decoding models. Moreover, linear analyses of CalM representations reveal interpretable functional structures beyond predictive accuracy. Taken together, we propose a novel and effective self-supervised pretraining paradigm for foundation models based on calcium traces, paving the way for scalable pretraining and broad applications in functional neural analysis. Code will be released soon.

Prior-guided Hierarchical Harmonization Network for Efficient Image Dehazing

Image dehazing is a crucial task that involves the enhancement of degraded images to recover their sharpness and textures. While vision Transformers have exhibited impressive results in diverse dehazing tasks, their quadratic complexity and lack of dehazing priors pose significant drawbacks for real-world applications. In this paper, guided by triple priors, Bright Channel Prior (BCP), Dark Channel Prior (DCP), and Histogram Equalization (HE), we propose a \textit{P}rior-\textit{g}uided Hierarchical \textit{H}armonization Network (PGH$^2$Net) for image dehazing. PGH$^2$Net is built upon the UNet-like architecture with an efficient encoder and decoder, consisting of two module types: (1) Prior aggregation module that injects B/DCP and selects diverse contexts with gating attention. (2) Feature harmonization modules that subtract low-frequency components from spatial and channel aspects and learn more informative feature distributions to equalize the feature maps.