Improve Language Model and Brain Alignment via Associative Memory

Associative memory engages in the integration of relevant information for comprehension in the human cognition system. In this work, we seek to improve alignment between language models and human brain while processing speech information by integrating associative memory. After verifying the alignment between language model and brain by mapping language model activations to brain activity, the original text stimuli expanded with simulated associative memory are regarded as input to computational language models. We find the alignment between language model and brain is improved in brain regions closely related to associative memory processing. We also demonstrate large language models after specific supervised fine-tuning better align with brain response, by building the \textit{Association} dataset containing 1000 samples of stories, with instructions encouraging associative memory as input and associated content as output.

Learn to Segment Retinal Lesions and Beyond

Towards automated retinal screening, this paper makes an endeavor to simultaneously achieve pixel-level retinal lesion segmentation and image-level disease classification. Such a multi-task approach is crucial for accurate and clinically interpretable disease diagnosis. Prior art is insufficient due to three challenges, that is, lesions lacking objective boundaries, clinical importance of lesions irrelevant to their size, and the lack of one-to-one correspondence between lesion and disease classes. This paper attacks the three challenges in the context of diabetic retinopathy (DR) grading. We propose L-Net, a new variant of fully convolutional networks, with its expansive path re-designed to tackle the first challenge. A dual loss that leverages both semantic segmentation and image classification losses is devised to resolve the second challenge. We propose Side-Attention Net (SiAN) as our multi-task framework. Harnessing L-Net as a side-attention branch, SiAN simultaneously improves DR grading and interprets the decision with lesion maps. A set of 12K fundus images is manually segmented by 45 ophthalmologists for 8 DR-related lesions, resulting in 290K manual segments in total. Extensive experiments on this large-scale dataset show that our proposed approach surpasses the prior art for multiple tasks including lesion segmentation, lesion classification and DR grading.