The NIPS'17 Competition: A Multi-View Ensemble Classification Model for Clinically Actionable Genetic Mutations

This paper presents details of our winning solutions to the task IV of NIPS 2017 Competition Track entitled Classifying Clinically Actionable Genetic Mutations. The machine learning task aims to classify genetic mutations based on text evidence from clinical literature with promising performance. We develop a novel multi-view machine learning framework with ensemble classification models to solve the problem. During the Challenge, feature combinations derived from three views including document view, entity text view, and entity name view, which complements each other, are comprehensively explored. As the final solution, we submitted an ensemble of nine basic gradient boosting models which shows the best performance in the evaluation. The approach scores 0.5506 and 0.6694 in terms of logarithmic loss on a fixed split in stage-1 testing phase and 5-fold cross validation respectively, which also makes us ranked as a top-1 team out of more than 1,300 solutions in NIPS 2017 Competition Track IV.

A natural language interface to a graph-based bibliographic information retrieval system

With the ever-increasing scientific literature, there is a need on a natural language interface to bibliographic information retrieval systems to retrieve related information effectively. In this paper, we propose a natural language interface, NLI-GIBIR, to a graph-based bibliographic information retrieval system. In designing NLI-GIBIR, we developed a novel framework that can be applicable to graph-based bibliographic information retrieval systems. Our framework integrates algorithms/heuristics for interpreting and analyzing natural language bibliographic queries. NLI-GIBIR allows users to search for a variety of bibliographic data through natural language. A series of text- and linguistic-based techniques are used to analyze and answer natural language queries, including tokenization, named entity recognition, and syntactic analysis. We find that our framework can effectively represents and addresses complex bibliographic information needs. Thus, the contributions of this paper are as follows: First, to our knowledge, it is the first attempt to propose a natural language interface to graph-based bibliographic information retrieval. Second, we propose a novel customized natural language processing framework that integrates a few original algorithms/heuristics for interpreting and analyzing natural language bibliographic queries. Third, we show that the proposed framework and natural language interface provide a practical solution in building real-world natural language interface-based bibliographic information retrieval systems. Our experimental results show that the presented system can correctly answer 39 out of 40 example natural language queries with varying lengths and complexities.