Towards Surgical World-Action Modeling: A Preliminary Joint Visual-Trajectory Forecasting for Surgical Motion Planning

Reliable surgical planning requires models to anticipate not only how instruments will move, but also how the operative visual state will evolve together with such motion. Existing approaches typically treat future scene generation and instrument trajectory prediction as two separate tasks. Scene-only models cannot directly evaluate the accuracy of future instrument motion at the trajectory level, while trajectory-only models fail to capture the visual consequences of instrument movement, leaving the consistency between predicted trajectories and future scene evolution unaddressed. Jointly forecasting both provides a more complete account of surgical action-scene dynamics by enabling explicit trajectory-level evaluation while simultaneously modeling the corresponding visual evolution. To bridge this gap, we present a preliminary joint visual-trajectory world-action model that simultaneously forecasts future visual states and instrument trajectories from historical surgical observations. Specifically, we encode historical video frames and tool trajectories into latent representations, which are processed by a temporal-spatial encoder and subsequently decoded through separate visual-state and trajectory prediction heads. Based on this preliminary architecture, a chunked autoregressive rollout is repeatedly applied to predict fifteen future steps. The chunked strategy consistently outperforms direct one-shot prediction across all evaluated horizons, improving first-segment PSNR from 18.86 to 23.11 dB and reducing ADE from 45.77 to 22.22 pixels. These results demonstrate the initial feasibility of joint visual-motion forecasting. However, we observe progressive visual degradation and accumulated trajectory errors over longer prediction horizons, which remain important challenges for future surgical world-action modeling.

SurgWMBench: A Vision-Based Benchmark for World-Modeling Surgical Instrument Motion Planning

Reliable surgical planning requires models that move beyond recognizing the current surgical step or imitating expert demonstrations, and instead anticipate how instrument motion reshapes subsequent operative states. Most surgical video understanding methods focus on recognizing phases, actions, or workflow states, while providing limited support for explicitly modeling instrument motion. Conversely, existing tool motion prediction methods can forecast instrument trajectories, but they generally do not capture the coupled evolution of future surgical video states. World models offer a natural framework for jointly modeling visual state transitions and instrument motion dynamics. However, existing surgical world model studies remain largely centered on visual generation quality, relying on generation-oriented metrics such as FVD and CD-FVD. These metrics are poorly aligned with instrument motion planning, as they do not directly measure whether predicted trajectories are geometrically accurate, temporally coherent, or actionable for downstream planning. This limitation is partly structural, since the field lacks public datasets and standardized evaluation protocols that provide the benchmarking infrastructure needed to assess motion-centric capabilities in surgical world models. In this paper, we introduce SurgWMBench, a vision-based benchmark for short-horizon surgical motion planning and dynamics prediction. Given intraoperative image sequences and historical instrument trajectory, SurgWMBench evaluates both near-future instrument motion prediction and stability under continuous rollout or input perturbations.

Unified Restoration-Perception Learning: Maritime Infrared-Visible Image Fusion and Segmentation

Marine scene understanding and segmentation plays a vital role in maritime monitoring and navigation safety. However, prevalent factors like fog and strong reflections in maritime environments cause severe image degradation, significantly compromising the stability of semantic perception. Existing restoration and enhancement methods typically target specific degradations or focus solely on visual quality, lacking end-to-end collaborative mechanisms that simultaneously improve structural recovery and semantic effectiveness. Moreover, publicly available infrared-visible datasets are predominantly collected from urban scenes, failing to capture the authentic characteristics of coupled degradations in marine environments. To address these challenges, the Infrared-Visible Maritime Ship Dataset (IVMSD) is proposed to cover various maritime scenarios under diverse weather and illumination conditions. Building upon this dataset, a Multi-task Complementary Learning Framework (MCLF) is proposed to collaboratively perform image restoration, multimodal fusion, and semantic segmentation within a unified architecture. The framework includes a Frequency-Spatial Enhancement Complementary (FSEC) module for degradation suppression and structural enhancement, a Semantic-Visual Consistency Attention (SVCA) module for semantic-consistent guidance, and a cross-modality guided attention mechanism for selective fusion. Experimental results on IVMSD demonstrate that the proposed method achieves state-of-the-art segmentation performance, significantly enhancing robustness and perceptual quality under complex maritime conditions.

PhenoProfiler: Advancing Phenotypic Learning for Image-based Drug Discovery

In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. However, existing methods require computationally extensive and complex multi-step procedures, which can introduce inefficiencies, limit generalizability, and increase potential errors. To address these challenges, we present PhenoProfiler, an innovative model designed to efficiently and effectively extract morphological representations, enabling the elucidation of phenotypic changes induced by treatments. PhenoProfiler is designed as an end-to-end tool that processes whole-slide multi-channel images directly into low-dimensional quantitative representations, eliminating the extensive computational steps required by existing methods. It also includes a multi-objective learning module to enhance robustness, accuracy, and generalization in morphological representation learning. PhenoProfiler is rigorously evaluated on large-scale publicly available datasets, including over 230,000 whole-slide multi-channel images in end-to-end scenarios and more than 8.42 million single-cell images in non-end-to-end settings. Across these benchmarks, PhenoProfiler consistently outperforms state-of-the-art methods by up to 20%, demonstrating substantial improvements in both accuracy and robustness. Furthermore, PhenoProfiler uses a tailored phenotype correction strategy to emphasize relative phenotypic changes under treatments, facilitating the detection of biologically meaningful signals. UMAP visualizations of treatment profiles demonstrate PhenoProfiler ability to effectively cluster treatments with similar biological annotations, thereby enhancing interpretability. These findings establish PhenoProfiler as a scalable, generalizable, and robust tool for phenotypic learning.