Knowledge Poisoning Attacks on Medical Multi-Modal Retrieval-Augmented Generation

Retrieval-augmented generation (RAG) is a widely adopted paradigm for enhancing LLMs in medical applications by incorporating expert multimodal knowledge during generation. However, the underlying retrieval databases may naturally contain, or be intentionally injected with, adversarial knowledge, which can perturb model outputs and undermine system reliability. To investigate this risk, prior studies have explored knowledge poisoning attacks in medical RAG systems. Nevertheless, most of them rely on the strong assumption that adversaries possess prior knowledge of user queries, which is unrealistic in deployments and substantially limits their practical applicability. In this paper, we propose M\textsuperscript{3}Att, a knowledge-poisoning framework designed for medical multimodal RAG systems, assuming only limited distribution knowledge of the underlying database. Our core idea is to inject covert misinformation into textual data while using paired visual data as a query-agnostic trigger to promote retrieval. We first propose a unified framework that introduces imperceptible perturbations to visual inputs to manipulate retrieval probabilities. Besides, due to the prior medical knowledge in LLMs, naively poisoned medical content with explicit factual errors can be corrected during generation. Thus, we leverage the inherent ambiguity of medical diagnosis and design a covert misinformation injection strategy that degrades diagnostic accuracy while evading model self-correction. Experiments on five LLMs and datasets demonstrate that M\textsuperscript{3}Att consistently produces clinically plausible yet incorrect generations. Codes: https://github.com/ypr17/M3Att.

Cross-Cultural Simulation of Citizen Emotional Responses to Bureaucratic Red Tape Using LLM Agents

Improving policymaking is a central concern in public administration. Prior human subject studies reveal substantial cross-cultural differences in citizens' emotional responses to red tape during policy implementation. While LLM agents offer opportunities to simulate human-like responses and reduce experimental costs, their ability to generate culturally appropriate emotional responses to red tape remains unverified. To address this gap, we propose an evaluation framework for assessing LLMs' emotional responses to red tape across diverse cultural contexts. As a pilot study, we apply this framework to a single red-tape scenario. Our results show that all models exhibit limited alignment with human emotional responses, with notably weaker performance in Eastern cultures. Cultural prompting strategies prove largely ineffective in improving alignment. We further introduce \textbf{RAMO}, an interactive interface for simulating citizens' emotional responses to red tape and for collecting human data to improve models. The interface is publicly available at https://ramo-chi.ivia.ch.