GuideSkill: Evolving Executable LLM Agent Skills for Guideline-Grounded Clinical Reasoning

Clinical practice guidelines (CPGs) encode diagnostic criteria, but LLM systems typically retrieve guideline text or absorb it through training rather than execute its rules. We introduce GuideSkill, an external reasoning layer that compiles disease-specific criteria into executable functions returning ordinal diagnostic-support scores. GuideSkill-Zero is initialized from guidelines, while GuideSkill-Evo uses case--diagnosis pairs to refine covered skills and add missing diagnoses. At inference, an LLM proposes a differential diagnosis, grounds the features required by each matched skill, and fuses its ranking with the executed skill scores. Across four benchmarks and four backbones, GuideSkill-Zero improves macro-average accuracy over guideline RAG by 13.45% on average. GuideSkill-Evo achieves the highest macro-average for every backbone, improves over direct inference by 18.49% relatively, and increases gold-label skill coverage from 56.5% to 99.5%. On Qwen3.5-9B, it also exceeds the strongest parameter-update baseline by 11.16% without updating the backbone. Expert evaluation further indicates that GuideSkill produces clinically sound and broadly acceptable skills, suggesting that its initialized and evolved rules are reliable and practically meaningful. These results support executable skills as a model-agnostic mechanism for combining guideline-derived procedures with case-derived diagnostic patterns.

ExpWeaver: LLM Agents Learn from Experience via Latent RAG

Experience learning has achieved promising results in enhancing LLM agent planning and reasoning by integrating past interactions as reusable knowledge. However, existing methods remain confined to explicit text space, retrieving experiences via semantic similarity and concatenating them into the context window, leading to substantial token overhead and a decoupled architecture that separates retrieval from generation. To address these limitations, we propose ExpWeaver, a framework that enables LLM agents to learn from experience via latent retrieval-augmented generation, without requiring a separate RAG module. ExpWeaver encodes experiences using the LLM's own hidden states, retrieves relevant experiences directly in latent space at each decoding step, and integrates them through cross-attention aggregation and gated residual mechanisms. The entire pipeline is optimized end-to-end with reinforcement learning, supporting both generative and ranking tasks. We evaluate ExpWeaver on 13 diverse tasks spanning question answering, reasoning, coding, scientific prediction, and recommendation. Results demonstrate that ExpWeaver achieves state-of-the-art performance on 12 out of 13 tasks, outperforming the strongest baseline by over 6.8%; maintains token efficiency comparable to non-retrieval baselines while text-based retrieval methods require 1.5 to 2 times more tokens; and exhibits superior cross-domain generalization, outperforming the strongest baseline by 16.32% under zero-shot transfer and 15.21% under few-shot transfer. Our code for ExpWeaver is released at https://github.com/ulab-uiuc/ExpWeaver.

ElasticMem: Latent Memory as a Learnable Resource for LLM Agents

Long-term memory is essential for LLM agents to reason coherently across extended interactions, personalize responses, and reuse past experience. However, existing memory-augmented methods typically treat memory as a fixed resource: text-space approaches concatenate retrieved memories into the context window, causing substantial token overhead and sensitivity to noisy evidence, while latent-space approaches reduce textual cost but still rely on rigid retrieval or fixed-capacity memory interfaces. This creates a mismatch between query-dependent memory utility and fixed memory allocation. We propose ElasticMem, a memory-augmented LLM framework that learns to use memory as an elastic latent resource. ElasticMem builds an offline latent memory bank with retrieval keys and content caches, retrieves memories adaptively from the reasoner's hidden state, assigns each retrieved memory a variable latent budget through a learned policy, and injects selected latent states as soft memory tokens for generation. The full memory-use process is optimized with downstream task rewards through group-relative policy optimization. We evaluate ElasticMem on MemorySuite, covering memory-intensive QA and embodied agent control. Across Qwen2.5-3B-Instruct and Qwen2.5-7B-Instruct backbones, ElasticMem improves weighted average QA accuracy by 26.2% and 24.6%, and improves ALFWorld success rate by 66.3% and 27.2%, respectively, over the strongest baselines, while achieving the lowest ALFWorld token cost. Ablations and qualitative analyses further show that adaptive retrieval and elastic budget allocation help ElasticMem prioritize useful evidence and transferable plans beyond rigid cosine similarity. Our code for ElasticMem will be released at https://github.com/ulab-uiuc/ElasticMem.

ExpGraph: Model-Agnostic Experience Learning with Graph-Structured Memory for LLM Agents

Large language model (LLM) agents have shown strong capabilities in reasoning, tool use, and multi-step interaction, but they often solve tasks from scratch and fail to reuse successful strategies or failure lessons from prior experience. Fine-tuning on collected experience can improve reuse, but it is inflexible when stronger or more suitable executors emerge. We propose ExpGraph, a model-agnostic experience learning framework that enables frozen and replaceable LLM executors to improve through external experience reuse without parameter updates. ExpGraph summarizes historical trajectories into reusable skills and failure lessons, organizes them as nodes in a self-evolving experience graph, and retrieves useful experiences through graph diffusion and utility-aware ranking. A lightweight retrieval copilot is trained with reinforcement learning using feedback that compares executor performance with and without retrieved experiences, while the graph is updated online from downstream task outcomes. We evaluate ExpGraph on ExpSuite, covering question answering, mathematical reasoning, code generation, and multi-step agentic environments including ALFWorld and AppWorld. ExpGraph improves over the strongest baseline by 12.2% and 4.7% on static tasks with smaller and larger executors, and by 21.4% and 12.7% in agentic environments, while reducing average interaction steps by 12.7% and 21.6%. Ablations show that graph-structured experience, utility-aware ranking, and adaptive retrieval jointly enable effective experience reuse across diverse tasks and executor models.