Current point cloud segmentation architectures suffer from limited long-range feature modeling, as they mostly rely on aggregating information with local neighborhoods. Furthermore, in order to learn point features at multiple scales, most methods utilize a data-agnostic sampling approach to decrease the number of points after each stage. Such sampling methods, however, often discard points for small objects in the early stages, leading to inadequate feature learning. We believe these issues are can be mitigated by introducing explicit geometry clues as guidance. To this end, we propose GeoSpark, a Plug-in module that incorporates Geometry clues into the network to Spark up feature learning and downsampling. GeoSpark can be easily integrated into various backbones. For feature aggregation, it improves feature modeling by allowing the network to learn from both local points and neighboring geometry partitions, resulting in an enlarged data-tailored receptive field. Additionally, GeoSpark utilizes geometry partition information to guide the downsampling process, where points with unique features are preserved while redundant points are fused, resulting in better preservation of key points throughout the network. We observed consistent improvements after adding GeoSpark to various backbones including PointNet++, KPConv, and PointTransformer. Notably, when integrated with Point Transformer, our GeoSpark module achieves a 74.7% mIoU on the ScanNetv2 dataset (4.1% improvement) and 71.5% mIoU on the S3DIS Area 5 dataset (1.1% improvement), ranking top on both benchmarks. Code and models will be made publicly available.
Whole slide image (WSI) has been widely used to assist automated diagnosis under the deep learning fields. However, most previous works only discuss the SINGLE task setting which is not aligned with real clinical setting, where pathologists often conduct multiple diagnosis tasks simultaneously. Also, it is commonly recognized that the multi-task learning paradigm can improve learning efficiency by exploiting commonalities and differences across multiple tasks. To this end, we present a novel multi-task framework (i.e., MulGT) for WSI analysis by the specially designed Graph-Transformer equipped with Task-aware Knowledge Injection and Domain Knowledge-driven Graph Pooling modules. Basically, with the Graph Neural Network and Transformer as the building commons, our framework is able to learn task-agnostic low-level local information as well as task-specific high-level global representation. Considering that different tasks in WSI analysis depend on different features and properties, we also design a novel Task-aware Knowledge Injection module to transfer the task-shared graph embedding into task-specific feature spaces to learn more accurate representation for different tasks. Further, we elaborately design a novel Domain Knowledge-driven Graph Pooling module for each task to improve both the accuracy and robustness of different tasks by leveraging different diagnosis patterns of multiple tasks. We evaluated our method on two public WSI datasets from TCGA projects, i.e., esophageal carcinoma and kidney carcinoma. Experimental results show that our method outperforms single-task counterparts and the state-of-theart methods on both tumor typing and staging tasks.
Traffic flow analysis is revolutionising traffic management. Qualifying traffic flow data, traffic control bureaus could provide drivers with real-time alerts, advising the fastest routes and therefore optimising transportation logistics and reducing congestion. The existing traffic flow datasets have two major limitations. They feature a limited number of classes, usually limited to one type of vehicle, and the scarcity of unlabelled data. In this paper, we introduce a new benchmark traffic flow image dataset called TrafficCAM. Our dataset distinguishes itself by two major highlights. Firstly, TrafficCAM provides both pixel-level and instance-level semantic labelling along with a large range of types of vehicles and pedestrians. It is composed of a large and diverse set of video sequences recorded in streets from eight Indian cities with stationary cameras. Secondly, TrafficCAM aims to establish a new benchmark for developing fully-supervised tasks, and importantly, semi-supervised learning techniques. It is the first dataset that provides a vast amount of unlabelled data, helping to better capture traffic flow qualification under a low cost annotation requirement. More precisely, our dataset has 4,402 image frames with semantic and instance annotations along with 59,944 unlabelled image frames. We validate our new dataset through a large and comprehensive range of experiments on several state-of-the-art approaches under four different settings: fully-supervised semantic and instance segmentation, and semi-supervised semantic and instance segmentation tasks. Our benchmark dataset will be released.
Learning medical visual representations directly from paired radiology reports has become an emerging topic in representation learning. However, existing medical image-text joint learning methods are limited by instance or local supervision analysis, ignoring disease-level semantic correspondences. In this paper, we present a novel Multi-Granularity Cross-modal Alignment (MGCA) framework for generalized medical visual representation learning by harnessing the naturally exhibited semantic correspondences between medical image and radiology reports at three different levels, i.e., pathological region-level, instance-level, and disease-level. Specifically, we first incorporate the instance-wise alignment module by maximizing the agreement between image-report pairs. Further, for token-wise alignment, we introduce a bidirectional cross-attention strategy to explicitly learn the matching between fine-grained visual tokens and text tokens, followed by contrastive learning to align them. More important, to leverage the high-level inter-subject relationship semantic (e.g., disease) correspondences, we design a novel cross-modal disease-level alignment paradigm to enforce the cross-modal cluster assignment consistency. Extensive experimental results on seven downstream medical image datasets covering image classification, object detection, and semantic segmentation tasks demonstrate the stable and superior performance of our framework.
Surgical action triplet recognition provides a better understanding of the surgical scene. This task is of high relevance as it provides to the surgeon with context-aware support and safety. The current go-to strategy for improving performance is the development of new network mechanisms. However, the performance of current state-of-the-art techniques is substantially lower than other surgical tasks. Why is this happening? This is the question that we address in this work. We present the first study to understand the failure of existing deep learning models through the lens of robustness and explainabilty. Firstly, we study current existing models under weak and strong $\delta-$perturbations via adversarial optimisation scheme. We then provide the failure modes via feature based explanations. Our study revels that the key for improving performance and increasing reliability is in the core and spurious attributes. Our work opens the door to more trustworthiness and reliability deep learning models in surgical science.
Modern deep neural networks struggle to transfer knowledge and generalize across domains when deploying to real-world applications. Domain generalization (DG) aims to learn a universal representation from multiple source domains to improve the network generalization ability on unseen target domains. Previous DG methods mostly focus on the data-level consistency scheme to advance the generalization capability of deep networks, without considering the synergistic regularization of different consistency schemes. In this paper, we present a novel Hierarchical Consistency framework for Domain Generalization (HCDG) by ensembling Extrinsic Consistency and Intrinsic Consistency. Particularly, for Extrinsic Consistency, we leverage the knowledge across multiple source domains to enforce data-level consistency. Also, we design a novel Amplitude Gaussian-mixing strategy for Fourier-based data augmentation to enhance such consistency. For Intrinsic Consistency, we perform task-level consistency for the same instance under the dual-task form. We evaluate the proposed HCDG framework on two medical image segmentation tasks, i.e., optic cup/disc segmentation on fundus images and prostate MRI segmentation. Extensive experimental results manifest the effectiveness and versatility of our HCDG framework. Code will be available once accept.
Annotation scarcity is a long-standing problem in medical image analysis area. To efficiently leverage limited annotations, abundant unlabeled data are additionally exploited in semi-supervised learning, while well-established cross-modality data are investigated in domain adaptation. In this paper, we aim to explore the feasibility of concurrently leveraging both unlabeled data and cross-modality data for annotation-efficient cardiac segmentation. To this end, we propose a cutting-edge semi-supervised domain adaptation framework, namely Dual-Teacher++. Besides directly learning from limited labeled target domain data (e.g., CT) via a student model adopted by previous literature, we design novel dual teacher models, including an inter-domain teacher model to explore cross-modality priors from source domain (e.g., MR) and an intra-domain teacher model to investigate the knowledge beneath unlabeled target domain. In this way, the dual teacher models would transfer acquired inter- and intra-domain knowledge to the student model for further integration and exploitation. Moreover, to encourage reliable dual-domain knowledge transfer, we enhance the inter-domain knowledge transfer on the samples with higher similarity to target domain after appearance alignment, and also strengthen intra-domain knowledge transfer of unlabeled target data with higher prediction confidence. In this way, the student model can obtain reliable dual-domain knowledge and yield improved performance on target domain data. We extensively evaluated the feasibility of our method on the MM-WHS 2017 challenge dataset. The experiments have demonstrated the superiority of our framework over other semi-supervised learning and domain adaptation methods. Moreover, our performance gains could be yielded in bidirections,i.e., adapting from MR to CT, and from CT to MR.
The whole slide histopathology images (WSIs) play a critical role in gastric cancer diagnosis. However, due to the large scale of WSIs and various sizes of the abnormal area, how to select informative regions and analyze them are quite challenging during the automatic diagnosis process. The multi-instance learning based on the most discriminative instances can be of great benefit for whole slide gastric image diagnosis. In this paper, we design a recalibrated multi-instance deep learning method (RMDL) to address this challenging problem. We first select the discriminative instances, and then utilize these instances to diagnose diseases based on the proposed RMDL approach. The designed RMDL network is capable of capturing instance-wise dependencies and recalibrating instance features according to the importance coefficient learned from the fused features. Furthermore, we build a large whole-slide gastric histopathology image dataset with detailed pixel-level annotations. Experimental results on the constructed gastric dataset demonstrate the significant improvement on the accuracy of our proposed framework compared with other state-of-the-art multi-instance learning methods. Moreover, our method is general and can be extended to other diagnosis tasks of different cancer types based on WSIs.
Deep convolutional neural networks have significantly boosted the performance of fundus image segmentation when test datasets have the same distribution as the training datasets. However, in clinical practice, medical images often exhibit variations in appearance for various reasons, e.g., different scanner vendors and image quality. These distribution discrepancies could lead the deep networks to over-fit on the training datasets and lack generalization ability on the unseen test datasets. To alleviate this issue, we present a novel Domain-oriented Feature Embedding (DoFE) framework to improve the generalization ability of CNNs on unseen target domains by exploring the knowledge from multiple source domains. Our DoFE framework dynamically enriches the image features with additional domain prior knowledge learned from multi-source domains to make the semantic features more discriminative. Specifically, we introduce a Domain Knowledge Pool to learn and memorize the prior information extracted from multi-source domains. Then the original image features are augmented with domain-oriented aggregated features, which are induced from the knowledge pool based on the similarity between the input image and multi-source domain images. We further design a novel domain code prediction branch to infer this similarity and employ an attention-guided mechanism to dynamically combine the aggregated features with the semantic features. We comprehensively evaluate our DoFE framework on two fundus image segmentation tasks, including the optic cup and disc segmentation and vessel segmentation. Our DoFE framework generates satisfying segmentation results on unseen datasets and surpasses other domain generalization and network regularization methods.
The success of deep convolutional neural networks is partially attributed to the massive amount of annotated training data. However, in practice, medical data annotations are usually expensive and time-consuming to be obtained. Considering multi-modality data with the same anatomic structures are widely available in clinic routine, in this paper, we aim to exploit the prior knowledge (e.g., shape priors) learned from one modality (aka., assistant modality) to improve the segmentation performance on another modality (aka., target modality) to make up annotation scarcity. To alleviate the learning difficulties caused by modality-specific appearance discrepancy, we first present an Image Alignment Module (IAM) to narrow the appearance gap between assistant and target modality data.We then propose a novel Mutual Knowledge Distillation (MKD) scheme to thoroughly exploit the modality-shared knowledge to facilitate the target-modality segmentation. To be specific, we formulate our framework as an integration of two individual segmentors. Each segmentor not only explicitly extracts one modality knowledge from corresponding annotations, but also implicitly explores another modality knowledge from its counterpart in mutual-guided manner. The ensemble of two segmentors would further integrate the knowledge from both modalities and generate reliable segmentation results on target modality. Experimental results on the public multi-class cardiac segmentation data, i.e., MMWHS 2017, show that our method achieves large improvements on CT segmentation by utilizing additional MRI data and outperforms other state-of-the-art multi-modality learning methods.