Hierarchical Vision-Language Learning for Medical Out-of-Distribution Detection

In trustworthy medical diagnosis systems, integrating out-of-distribution (OOD) detection aims to identify unknown diseases in samples, thereby mitigating the risk of misdiagnosis. In this study, we propose a novel OOD detection framework based on vision-language models (VLMs), which integrates hierarchical visual information to cope with challenging unknown diseases that resemble known diseases. Specifically, a cross-scale visual fusion strategy is proposed to couple visual embeddings from multiple scales. This enriches the detailed representation of medical images and thus improves the discrimination of unknown diseases. Moreover, a cross-scale hard pseudo-OOD sample generation strategy is proposed to benefit OOD detection maximally. Experimental evaluations on three public medical datasets support that the proposed framework achieves superior OOD detection performance compared to existing methods. The source code is available at https://openi.pcl.ac.cn/OpenMedIA/HVL.

Lite-SAM Is Actually What You Need for Segment Everything

This paper introduces Lite-SAM, an efficient end-to-end solution for the SegEvery task designed to reduce computational costs and redundancy. Lite-SAM is composed of four main components: a streamlined CNN-Transformer hybrid encoder (LiteViT), an automated prompt proposal network (AutoPPN), a traditional prompt encoder, and a mask decoder. All these components are integrated within the SAM framework. Our LiteViT, a high-performance lightweight backbone network, has only 1.16M parameters, which is a 23% reduction compared to the lightest existing backbone network Shufflenet. We also introduce AutoPPN, an innovative end-to-end method for prompt boxes and points generation. This is an improvement over traditional grid search sampling methods, and its unique design allows for easy integration into any SAM series algorithm, extending its usability. we have thoroughly benchmarked Lite-SAM across a plethora of both public and private datasets. The evaluation encompassed a broad spectrum of universal metrics, including the number of parameters, SegEvery execution time, and accuracy. The findings reveal that Lite-SAM, operating with a lean 4.2M parameters, significantly outpaces its counterparts, demonstrating performance improvements of 43x, 31x, 20x, 21x, and 1.6x over SAM, MobileSAM, Edge-SAM, EfficientViT-SAM, and MobileSAM-v2 respectively, all the while maintaining competitive accuracy. This underscores Lite-SAM's prowess in achieving an optimal equilibrium between performance and precision, thereby setting a new state-of-the-art(SOTA) benchmark in the domain.