DynProto: Dynamic Prototype Evolution for Out-of-Distribution Detection

Recent studies show that using potential out-of-distribution (OOD) labels from large corpora as auxiliary information can improve OOD detection in vision-language models (VLMs). However, these methods often fail when real-world OOD samples fall outside the predefined OOD label set. To address this limitation, we propose DynProto, a novel approach that learns OOD prototypes dynamically during testing using only in-distribution (ID) information. DynProto is inspired by a key observation: OOD samples predicted as the same ID class tend to cluster in the feature space. With this insight, we leverage easy-to-detect OOD samples as ``anchors'' to find their harder-to-detect, similar counterparts. To this end, DynProto introduces two modules: \textbf{Coarse OOD Pattern Capturing Module} caches OOD patterns that are easily confused with each ID class during testing, and \textbf{Fine-grained OOD Pattern Refinement Module} subsequently clusters these patterns within each cache and aggregates them into representative OOD prototypes. By measuring similarity to ID and dynamic OOD prototypes, DynProto enables accurate OOD detection. DynProto significantly outperforms prior methods across multiple benchmarks. On ImageNet OOD benchmark, DynProto reduces FPR95 by 11.60\% and improves AUROC by 4.70\%. Moreover, the framework is architecture-agnostic and can be integrated into various backbones.

DCAC: Dynamic Class-Aware Cache Creates Stronger Out-of-Distribution Detectors

Out-of-distribution (OOD) detection remains a fundamental challenge for deep neural networks, particularly due to overconfident predictions on unseen OOD samples during testing. We reveal a key insight: OOD samples predicted as the same class, or given high probabilities for it, are visually more similar to each other than to the true in-distribution (ID) samples. Motivated by this class-specific observation, we propose DCAC (Dynamic Class-Aware Cache), a training-free, test-time calibration module that maintains separate caches for each ID class to collect high-entropy samples and calibrate the raw predictions of input samples. DCAC leverages cached visual features and predicted probabilities through a lightweight two-layer module to mitigate overconfident predictions on OOD samples. This module can be seamlessly integrated with various existing OOD detection methods across both unimodal and vision-language models while introducing minimal computational overhead. Extensive experiments on multiple OOD benchmarks demonstrate that DCAC significantly enhances existing methods, achieving substantial improvements, i.e., reducing FPR95 by 6.55% when integrated with ASH-S on ImageNet OOD benchmark.

Hierarchical Vision-Language Learning for Medical Out-of-Distribution Detection

In trustworthy medical diagnosis systems, integrating out-of-distribution (OOD) detection aims to identify unknown diseases in samples, thereby mitigating the risk of misdiagnosis. In this study, we propose a novel OOD detection framework based on vision-language models (VLMs), which integrates hierarchical visual information to cope with challenging unknown diseases that resemble known diseases. Specifically, a cross-scale visual fusion strategy is proposed to couple visual embeddings from multiple scales. This enriches the detailed representation of medical images and thus improves the discrimination of unknown diseases. Moreover, a cross-scale hard pseudo-OOD sample generation strategy is proposed to benefit OOD detection maximally. Experimental evaluations on three public medical datasets support that the proposed framework achieves superior OOD detection performance compared to existing methods. The source code is available at https://openi.pcl.ac.cn/OpenMedIA/HVL.