DCAC: Dynamic Class-Aware Cache Creates Stronger Out-of-Distribution Detectors

Out-of-distribution (OOD) detection remains a fundamental challenge for deep neural networks, particularly due to overconfident predictions on unseen OOD samples during testing. We reveal a key insight: OOD samples predicted as the same class, or given high probabilities for it, are visually more similar to each other than to the true in-distribution (ID) samples. Motivated by this class-specific observation, we propose DCAC (Dynamic Class-Aware Cache), a training-free, test-time calibration module that maintains separate caches for each ID class to collect high-entropy samples and calibrate the raw predictions of input samples. DCAC leverages cached visual features and predicted probabilities through a lightweight two-layer module to mitigate overconfident predictions on OOD samples. This module can be seamlessly integrated with various existing OOD detection methods across both unimodal and vision-language models while introducing minimal computational overhead. Extensive experiments on multiple OOD benchmarks demonstrate that DCAC significantly enhances existing methods, achieving substantial improvements, i.e., reducing FPR95 by 6.55% when integrated with ASH-S on ImageNet OOD benchmark.

Hierarchical Vision-Language Learning for Medical Out-of-Distribution Detection

In trustworthy medical diagnosis systems, integrating out-of-distribution (OOD) detection aims to identify unknown diseases in samples, thereby mitigating the risk of misdiagnosis. In this study, we propose a novel OOD detection framework based on vision-language models (VLMs), which integrates hierarchical visual information to cope with challenging unknown diseases that resemble known diseases. Specifically, a cross-scale visual fusion strategy is proposed to couple visual embeddings from multiple scales. This enriches the detailed representation of medical images and thus improves the discrimination of unknown diseases. Moreover, a cross-scale hard pseudo-OOD sample generation strategy is proposed to benefit OOD detection maximally. Experimental evaluations on three public medical datasets support that the proposed framework achieves superior OOD detection performance compared to existing methods. The source code is available at https://openi.pcl.ac.cn/OpenMedIA/HVL.