Curriculum Abductive Learning

Abductive Learning (ABL) integrates machine learning with logical reasoning in a loop: a learning model predicts symbolic concept labels from raw inputs, which are revised through abduction using domain knowledge and then fed back for retraining. However, due to the nondeterminism of abduction, the training process often suffers from instability, especially when the knowledge base is large and complex, resulting in a prohibitively large abduction space. While prior works focus on improving candidate selection within this space, they typically treat the knowledge base as a static black box. In this work, we propose Curriculum Abductive Learning (C-ABL), a method that explicitly leverages the internal structure of the knowledge base to address the ABL training challenges. C-ABL partitions the knowledge base into a sequence of sub-bases, progressively introduced during training. This reduces the abduction space throughout training and enables the model to incorporate logic in a stepwise, smooth way. Experiments across multiple tasks show that C-ABL outperforms previous ABL implementations, significantly improves training stability, convergence speed, and final accuracy, especially under complex knowledge setting.

Horizon-wise Learning Paradigm Promotes Gene Splicing Identification

Identifying gene splicing is a core and significant task confronted in modern collaboration between artificial intelligence and bioinformatics. Past decades have witnessed great efforts on this concern, such as the bio-plausible splicing pattern AT-CG and the famous SpliceAI. In this paper, we propose a novel framework for the task of gene splicing identification, named Horizon-wise Gene Splicing Identification (H-GSI). The proposed H-GSI follows the horizon-wise identification paradigm and comprises four components: the pre-processing procedure transforming string data into tensors, the sliding window technique handling long sequences, the SeqLab model, and the predictor. In contrast to existing studies that process gene information with a truncated fixed-length sequence, H-GSI employs a horizon-wise identification paradigm in which all positions in a sequence are predicted with only one forward computation, improving accuracy and efficiency. The experiments conducted on the real-world Human dataset show that our proposed H-GSI outperforms SpliceAI and achieves the best accuracy of 97.20\%. The source code is available from this link.