MedInsight: A Multi-Source Context Augmentation Framework for Generating Patient-Centric Medical Responses using Large Language Models

Large Language Models (LLMs) have shown impressive capabilities in generating human-like responses. However, their lack of domain-specific knowledge limits their applicability in healthcare settings, where contextual and comprehensive responses are vital. To address this challenge and enable the generation of patient-centric responses that are contextually relevant and comprehensive, we propose MedInsight:a novel retrieval augmented framework that augments LLM inputs (prompts) with relevant background information from multiple sources. MedInsight extracts pertinent details from the patient's medical record or consultation transcript. It then integrates information from authoritative medical textbooks and curated web resources based on the patient's health history and condition. By constructing an augmented context combining the patient's record with relevant medical knowledge, MedInsight generates enriched, patient-specific responses tailored for healthcare applications such as diagnosis, treatment recommendations, or patient education. Experiments on the MTSamples dataset validate MedInsight's effectiveness in generating contextually appropriate medical responses. Quantitative evaluation using the Ragas metric and TruLens for answer similarity and answer correctness demonstrates the model's efficacy. Furthermore, human evaluation studies involving Subject Matter Expert (SMEs) confirm MedInsight's utility, with moderate inter-rater agreement on the relevance and correctness of the generated responses.

Advancing Generative Model Evaluation: A Novel Algorithm for Realistic Image Synthesis and Comparison in OCR System

This research addresses a critical challenge in the field of generative models, particularly in the generation and evaluation of synthetic images. Given the inherent complexity of generative models and the absence of a standardized procedure for their comparison, our study introduces a pioneering algorithm to objectively assess the realism of synthetic images. This approach significantly enhances the evaluation methodology by refining the Fr\'echet Inception Distance (FID) score, allowing for a more precise and subjective assessment of image quality. Our algorithm is particularly tailored to address the challenges in generating and evaluating realistic images of Arabic handwritten digits, a task that has traditionally been near-impossible due to the subjective nature of realism in image generation. By providing a systematic and objective framework, our method not only enables the comparison of different generative models but also paves the way for improvements in their design and output. This breakthrough in evaluation and comparison is crucial for advancing the field of OCR, especially for scripts that present unique complexities, and sets a new standard in the generation and assessment of high-quality synthetic images.

Patient-Centric Knowledge Graphs: A Survey of Current Methods, Challenges, and Applications

Patient-Centric Knowledge Graphs (PCKGs) represent an important shift in healthcare that focuses on individualized patient care by mapping the patient's health information in a holistic and multi-dimensional way. PCKGs integrate various types of health data to provide healthcare professionals with a comprehensive understanding of a patient's health, enabling more personalized and effective care. This literature review explores the methodologies, challenges, and opportunities associated with PCKGs, focusing on their role in integrating disparate healthcare data and enhancing patient care through a unified health perspective. In addition, this review also discusses the complexities of PCKG development, including ontology design, data integration techniques, knowledge extraction, and structured representation of knowledge. It highlights advanced techniques such as reasoning, semantic search, and inference mechanisms essential in constructing and evaluating PCKGs for actionable healthcare insights. We further explore the practical applications of PCKGs in personalized medicine, emphasizing their significance in improving disease prediction and formulating effective treatment plans. Overall, this review provides a foundational perspective on the current state-of-the-art and best practices of PCKGs, guiding future research and applications in this dynamic field.