Benchmarking LLM Causal Reasoning with Scientifically Validated Relationships

Causal reasoning is fundamental for Large Language Models (LLMs) to understand genuine cause-and-effect relationships beyond pattern matching. Existing benchmarks suffer from critical limitations such as reliance on synthetic data and narrow domain coverage. We introduce a novel benchmark constructed from casually identified relationships extracted from top-tier economics and finance journals, drawing on rigorous methodologies including instrumental variables, difference-in-differences, and regression discontinuity designs. Our benchmark comprises 40,379 evaluation items covering five task types across domains such as health, environment, technology, law, and culture. Experimental results on eight state-of-the-art LLMs reveal substantial limitations, with the best model achieving only 57.6\% accuracy. Moreover, model scale does not consistently translate to superior performance, and even advanced reasoning models struggle with fundamental causal relationship identification. These findings underscore a critical gap between current LLM capabilities and demands of reliable causal reasoning in high-stakes applications.

Bilinear relational structure fixes reversal curse and enables consistent model editing

The reversal curse -- a language model's (LM) inability to infer an unseen fact ``B is A'' from a learned fact ``A is B'' -- is widely considered a fundamental limitation. We show that this is not an inherent failure but an artifact of how models encode knowledge. By training LMs from scratch on a synthetic dataset of relational knowledge graphs, we demonstrate that bilinear relational structure emerges in their hidden representations. This structure substantially alleviates the reversal curse, enabling LMs to infer unseen reverse facts. Crucially, we also find that this bilinear structure plays a key role in consistent model editing. When a fact is updated in a LM with this structure, the edit correctly propagates to its reverse and other logically dependent facts. In contrast, models lacking this representation not only suffer from the reversal curse but also fail to generalize edits, further introducing logical inconsistencies. Our results establish that training on a relational knowledge dataset induces the emergence of bilinear internal representations, which in turn enable LMs to behave in a logically consistent manner after editing. This implies that the success of model editing depends critically not just on editing algorithms but on the underlying representational geometry of the knowledge being modified.

Erase or Hide? Suppressing Spurious Unlearning Neurons for Robust Unlearning

Large language models trained on web-scale data can memorize private or sensitive knowledge, raising significant privacy risks. Although some unlearning methods mitigate these risks, they remain vulnerable to "relearning" during subsequent training, allowing a substantial portion of forgotten knowledge to resurface. In this paper, we show that widely used unlearning methods cause shallow alignment: instead of faithfully erasing target knowledge, they generate spurious unlearning neurons that amplify negative influence to hide it. To overcome this limitation, we introduce Ssiuu, a new class of unlearning methods that employs attribution-guided regularization to prevent spurious negative influence and faithfully remove target knowledge. Experimental results confirm that our method reliably erases target knowledge and outperforms strong baselines across two practical retraining scenarios: (1) adversarial injection of private data, and (2) benign attack using an instruction-following benchmark. Our findings highlight the necessity of robust and faithful unlearning methods for safe deployment of language models.

GeoReg: Weight-Constrained Few-Shot Regression for Socio-Economic Estimation using LLM

Socio-economic indicators like regional GDP, population, and education levels, are crucial to shaping policy decisions and fostering sustainable development. This research introduces GeoReg a regression model that integrates diverse data sources, including satellite imagery and web-based geospatial information, to estimate these indicators even for data-scarce regions such as developing countries. Our approach leverages the prior knowledge of large language model (LLM) to address the scarcity of labeled data, with the LLM functioning as a data engineer by extracting informative features to enable effective estimation in few-shot settings. Specifically, our model obtains contextual relationships between data features and the target indicator, categorizing their correlations as positive, negative, mixed, or irrelevant. These features are then fed into the linear estimator with tailored weight constraints for each category. To capture nonlinear patterns, the model also identifies meaningful feature interactions and integrates them, along with nonlinear transformations. Experiments across three countries at different stages of development demonstrate that our model outperforms baselines in estimating socio-economic indicators, even for low-income countries with limited data availability.

Exploring Persona-dependent LLM Alignment for the Moral Machine Experiment

Deploying large language models (LLMs) with agency in real-world applications raises critical questions about how these models will behave. In particular, how will their decisions align with humans when faced with moral dilemmas? This study examines the alignment between LLM-driven decisions and human judgment in various contexts of the moral machine experiment, including personas reflecting different sociodemographics. We find that the moral decisions of LLMs vary substantially by persona, showing greater shifts in moral decisions for critical tasks than humans. Our data also indicate an interesting partisan sorting phenomenon, where political persona predominates the direction and degree of LLM decisions. We discuss the ethical implications and risks associated with deploying these models in applications that involve moral decisions.

Recent advances in interpretable machine learning using structure-based protein representations

Recent advancements in machine learning (ML) are transforming the field of structural biology. For example, AlphaFold, a groundbreaking neural network for protein structure prediction, has been widely adopted by researchers. The availability of easy-to-use interfaces and interpretable outcomes from the neural network architecture, such as the confidence scores used to color the predicted structures, have made AlphaFold accessible even to non-ML experts. In this paper, we present various methods for representing protein 3D structures from low- to high-resolution, and show how interpretable ML methods can support tasks such as predicting protein structures, protein function, and protein-protein interactions. This survey also emphasizes the significance of interpreting and visualizing ML-based inference for structure-based protein representations that enhance interpretability and knowledge discovery. Developing such interpretable approaches promises to further accelerate fields including drug development and protein design.

Persona Setting Pitfall: Persistent Outgroup Biases in Large Language Models Arising from Social Identity Adoption

Drawing parallels between human cognition and artificial intelligence, we explored how large language models (LLMs) internalize identities imposed by targeted prompts. Informed by Social Identity Theory, these identity assignments lead LLMs to distinguish between "we" (the ingroup) and "they" (the outgroup). This self-categorization generates both ingroup favoritism and outgroup bias. Nonetheless, existing literature has predominantly focused on ingroup favoritism, often overlooking outgroup bias, which is a fundamental source of intergroup prejudice and discrimination. Our experiment addresses this gap by demonstrating that outgroup bias manifests as strongly as ingroup favoritism. Furthermore, we successfully mitigated the inherent pro-liberal, anti-conservative bias in LLMs by guiding them to adopt the perspectives of the initially disfavored group. These results were replicated in the context of gender bias. Our findings highlight the potential to develop more equitable and balanced language models.

Adversarial Style Augmentation via Large Language Model for Robust Fake News Detection

The spread of fake news negatively impacts individuals and is regarded as a significant social challenge that needs to be addressed. A number of algorithmic and insightful features have been identified for detecting fake news. However, with the recent LLMs and their advanced generation capabilities, many of the detectable features (e.g., style-conversion attacks) can be altered, making it more challenging to distinguish from real news. This study proposes adversarial style augmentation, AdStyle, to train a fake news detector that remains robust against various style-conversion attacks. Our model's key mechanism is the careful use of LLMs to automatically generate a diverse yet coherent range of style-conversion attack prompts. This improves the generation of prompts that are particularly difficult for the detector to handle. Experiments show that our augmentation strategy improves robustness and detection performance when tested on fake news benchmark datasets.

Generalizable Disaster Damage Assessment via Change Detection with Vision Foundation Model

The increasing frequency and intensity of natural disasters demand more sophisticated approaches for rapid and precise damage assessment. To tackle this issue, researchers have developed various methods on disaster benchmark datasets from satellite imagery to aid in detecting disaster damage. However, the diverse nature of geographical landscapes and disasters makes it challenging to apply existing methods to regions unseen during training. We present DAVI (Disaster Assessment with VIsion foundation model), which overcomes domain disparities and detects structural damage (e.g., building) without requiring ground-truth labels of the target region. DAVI integrates task-specific knowledge from a model trained on source regions with an image segmentation foundation model to generate pseudo labels of possible damage in the target region. It then employs a two-stage refinement process, targeting both the pixel and overall image, to more accurately pinpoint changes in disaster-struck areas based on before-and-after images. Comprehensive evaluations demonstrate that DAVI achieves exceptional performance across diverse terrains (e.g., USA and Mexico) and disaster types (e.g., wildfires, hurricanes, and earthquakes). This confirms its robustness in assessing disaster impact without dependence on ground-truth labels.

Robust Optimization in Protein Fitness Landscapes Using Reinforcement Learning in Latent Space

Proteins are complex molecules responsible for different functions in nature. Enhancing the functionality of proteins and cellular fitness can significantly impact various industries. However, protein optimization using computational methods remains challenging, especially when starting from low-fitness sequences. We propose LatProtRL, an optimization method to efficiently traverse a latent space learned by an encoder-decoder leveraging a large protein language model. To escape local optima, our optimization is modeled as a Markov decision process using reinforcement learning acting directly in latent space. We evaluate our approach on two important fitness optimization tasks, demonstrating its ability to achieve comparable or superior fitness over baseline methods. Our findings and in vitro evaluation show that the generated sequences can reach high-fitness regions, suggesting a substantial potential of LatProtRL in lab-in-the-loop scenarios.