Gall Bladder Cancer Detection from US Images with Only Image Level Labels

Automated detection of Gallbladder Cancer (GBC) from Ultrasound (US) images is an important problem, which has drawn increased interest from researchers. However, most of these works use difficult-to-acquire information such as bounding box annotations or additional US videos. In this paper, we focus on GBC detection using only image-level labels. Such annotation is usually available based on the diagnostic report of a patient, and do not require additional annotation effort from the physicians. However, our analysis reveals that it is difficult to train a standard image classification model for GBC detection. This is due to the low inter-class variance (a malignant region usually occupies only a small portion of a US image), high intra-class variance (due to the US sensor capturing a 2D slice of a 3D object leading to large viewpoint variations), and low training data availability. We posit that even when we have only the image level label, still formulating the problem as object detection (with bounding box output) helps a deep neural network (DNN) model focus on the relevant region of interest. Since no bounding box annotations is available for training, we pose the problem as weakly supervised object detection (WSOD). Motivated by the recent success of transformer models in object detection, we train one such model, DETR, using multi-instance-learning (MIL) with self-supervised instance selection to suit the WSOD task. Our proposed method demonstrates an improvement of AP and detection sensitivity over the SOTA transformer-based and CNN-based WSOD methods. Project page is at https://gbc-iitd.github.io/wsod-gbc

RadFormer: Transformers with Global-Local Attention for Interpretable and Accurate Gallbladder Cancer Detection

We propose a novel deep neural network architecture to learn interpretable representation for medical image analysis. Our architecture generates a global attention for region of interest, and then learns bag of words style deep feature embeddings with local attention. The global, and local feature maps are combined using a contemporary transformer architecture for highly accurate Gallbladder Cancer (GBC) detection from Ultrasound (USG) images. Our experiments indicate that the detection accuracy of our model beats even human radiologists, and advocates its use as the second reader for GBC diagnosis. Bag of words embeddings allow our model to be probed for generating interpretable explanations for GBC detection consistent with the ones reported in medical literature. We show that the proposed model not only helps understand decisions of neural network models but also aids in discovery of new visual features relevant to the diagnosis of GBC. Source-code and model will be available at https://github.com/sbasu276/RadFormer

Unsupervised Contrastive Learning of Image Representations from Ultrasound Videos with Hard Negative Mining

Rich temporal information and variations in viewpoints make video data an attractive choice for learning image representations using unsupervised contrastive learning (UCL) techniques. State-of-the-art (SOTA) contrastive learning techniques consider frames within a video as positives in the embedding space, whereas the frames from other videos are considered negatives. We observe that unlike multiple views of an object in natural scene videos, an Ultrasound (US) video captures different 2D slices of an organ. Hence, there is almost no similarity between the temporally distant frames of even the same US video. In this paper we propose to instead utilize such frames as hard negatives. We advocate mining both intra-video and cross-video negatives in a hardness-sensitive negative mining curriculum in a UCL framework to learn rich image representations. We deploy our framework to learn the representations of Gallbladder (GB) malignancy from US videos. We also construct the first large-scale US video dataset containing 64 videos and 15,800 frames for learning GB representations. We show that the standard ResNet50 backbone trained with our framework improves the accuracy of models pretrained with SOTA UCL techniques as well as supervised pretrained models on ImageNet for the GB malignancy detection task by 2-6%. We further validate the generalizability of our method on a publicly available lung US image dataset of COVID-19 pathologies and show an improvement of 1.5% compared to SOTA. Source code, dataset, and models are available at https://gbc-iitd.github.io/usucl.

Surpassing the Human Accuracy: Detecting Gallbladder Cancer from USG Images with Curriculum Learning

We explore the potential of CNN-based models for gallbladder cancer (GBC) detection from ultrasound (USG) images as no prior study is known. USG is the most common diagnostic modality for GB diseases due to its low cost and accessibility. However, USG images are challenging to analyze due to low image quality, noise, and varying viewpoints due to the handheld nature of the sensor. Our exhaustive study of state-of-the-art (SOTA) image classification techniques for the problem reveals that they often fail to learn the salient GB region due to the presence of shadows in the USG images. SOTA object detection techniques also achieve low accuracy because of spurious textures due to noise or adjacent organs. We propose GBCNet to tackle the challenges in our problem. GBCNet first extracts the regions of interest (ROIs) by detecting the GB (and not the cancer), and then uses a new multi-scale, second-order pooling architecture specializing in classifying GBC. To effectively handle spurious textures, we propose a curriculum inspired by human visual acuity, which reduces the texture biases in GBCNet. Experimental results demonstrate that GBCNet significantly outperforms SOTA CNN models, as well as the expert radiologists. Our technical innovations are generic to other USG image analysis tasks as well. Hence, as a validation, we also show the efficacy of GBCNet in detecting breast cancer from USG images. Project page with source code, trained models, and data is available at https://gbc-iitd.github.io/gbcnet

A Supervised Learning Approach for Robust Health Monitoring using Face Videos

Monitoring of cardiovascular activity is highly desired and can enable novel applications in diagnosing potential cardiovascular diseases and maintaining an individual's well-being. Currently, such vital signs are measured using intrusive contact devices such as an electrocardiogram (ECG), chest straps, and pulse oximeters that require the patient or the health provider to manually implement. Non-contact, device-free human sensing methods can eliminate the need for specialized heart and blood pressure monitoring equipment. Non-contact methods can have additional advantages since they are scalable with any environment where video can be captured, can be used for continuous measurements, and can be used on patients with varying levels of dexterity and independence, from people with physical impairments to infants (e.g., baby camera). In this paper, we used a non-contact method that only requires face videos recorded using commercially-available webcams. These videos were exploited to predict the health attributes like pulse rate and variance in pulse rate. The proposed approach used facial recognition to detect the face in each frame of the video using facial landmarks, followed by supervised learning using deep neural networks to train the machine learning model. The videos captured subjects performing different physical activities that result in varying cardiovascular responses. The proposed method did not require training data from every individual and thus the prediction can be obtained for the new individuals for which there is no prior data; critical in approach generalization. The approach was also evaluated on a dataset of people with different ethnicity. The proposed approach had less than a 4.6\% error in predicting the pulse rate.

Improving Human-Labeled Data through Dynamic Automatic Conflict Resolution

This paper develops and implements a scalable methodology for (a) estimating the noisiness of labels produced by a typical crowdsourcing semantic annotation task, and (b) reducing the resulting error of the labeling process by as much as 20-30% in comparison to other common labeling strategies. Importantly, this new approach to the labeling process, which we name Dynamic Automatic Conflict Resolution (DACR), does not require a ground truth dataset and is instead based on inter-project annotation inconsistencies. This makes DACR not only more accurate but also available to a broad range of labeling tasks. In what follows we present results from a text classification task performed at scale for a commercial personal assistant, and evaluate the inherent ambiguity uncovered by this annotation strategy as compared to other common labeling strategies.

Covfefe: A Computer Vision Approach For Estimating Force Exertion

Cumulative exposure to repetitive and forceful activities may lead to musculoskeletal injuries which not only reduce workers' efficiency and productivity, but also affect their quality of life. Thus, widely accessible techniques for reliable detection of unsafe muscle force exertion levels for human activity is necessary for their well-being. However, measurement of force exertion levels is challenging and the existing techniques pose a great challenge as they are either intrusive, interfere with human-machine interface, and/or subjective in the nature, thus are not scalable for all workers. In this work, we use face videos and the photoplethysmography (PPG) signals to classify force exertion levels of 0\%, 50\%, and 100\% (representing rest, moderate effort, and high effort), thus providing a non-intrusive and scalable approach. Efficient feature extraction approaches have been investigated, including standard deviation of the movement of different landmarks of the face, distances between peaks and troughs in the PPG signals. We note that the PPG signals can be obtained from the face videos, thus giving an efficient classification algorithm for the force exertion levels using face videos. Based on the data collected from 20 subjects, features extracted from the face videos give 90\% accuracy in classification among the 100\% and the combination of 0\% and 50\% datasets. Further combining the PPG signals provide 81.7\% accuracy. The approach is also shown to be robust to the correctly identify force level when the person is talking, even though such datasets are not included in the training.

Parametric Synthesis of Text on Stylized Backgrounds using PGGANs

We describe a novel method of generating high-resolution real-world images of text where the style and textual content of the images are described parametrically. Our method combines text to image retrieval techniques with progressive growing of Generative Adversarial Networks (PGGANs) to achieve conditional generation of photo-realistic images that reflect specific styles, as well as artifacts seen in real-world images. We demonstrate our method in the context of automotive license plates. We assess the impact of varying the number of training images of each style on the fidelity of the generated style, and demonstrate the quality of the generated images using license plate recognition systems.

Learning to Navigate Autonomously in Outdoor Environments : MAVNet

In the modern era of automation and robotics, autonomous vehicles are currently the focus of academic and industrial research. With the ever increasing number of unmanned aerial vehicles getting involved in activities in the civilian and commercial domain, there is an increased need for autonomy in these systems too. Due to guidelines set by the governments regarding the operation ceiling of civil drones, road-tracking based navigation is garnering interest . In an attempt to achieve the above mentioned tasks, we propose an imitation learning based, data-driven solution to UAV autonomy for navigating through city streets by learning to fly by imitating an expert pilot. Derived from the classic image classification algorithms, our classifier has been constructed in the form of a fast 39-layered Inception model, that evaluates the presence of roads using the tomographic reconstructions of the input frames. Based on the Inception-v3 architecture, our system performs better in terms of processing complexity and accuracy than many existing models for imitation learning. The data used for training the system has been captured from the drone, by flying it in and around urban and semi-urban streets, by experts having at least 6-8 years of flying experience. Permissions were taken from required authorities who made sure that minimal risk (to pedestrians) is involved in the data collection process. With the extensive amount of drone data that we collected, we have been able to navigate successfully through roads without crashing or overshooting, with an accuracy of 98.44%. The computational efficiency of MAVNet enables the drone to fly at high speeds of upto 6m/sec. We present the same results in this research and compare them with other state-of-the-art methods of vision and learning based navigation.

Compressive Light Field Reconstructions using Deep Learning

Light field imaging is limited in its computational processing demands of high sampling for both spatial and angular dimensions. Single-shot light field cameras sacrifice spatial resolution to sample angular viewpoints, typically by multiplexing incoming rays onto a 2D sensor array. While this resolution can be recovered using compressive sensing, these iterative solutions are slow in processing a light field. We present a deep learning approach using a new, two branch network architecture, consisting jointly of an autoencoder and a 4D CNN, to recover a high resolution 4D light field from a single coded 2D image. This network decreases reconstruction time significantly while achieving average PSNR values of 26-32 dB on a variety of light fields. In particular, reconstruction time is decreased from 35 minutes to 6.7 minutes as compared to the dictionary method for equivalent visual quality. These reconstructions are performed at small sampling/compression ratios as low as 8%, allowing for cheaper coded light field cameras. We test our network reconstructions on synthetic light fields, simulated coded measurements of real light fields captured from a Lytro Illum camera, and real coded images from a custom CMOS diffractive light field camera. The combination of compressive light field capture with deep learning allows the potential for real-time light field video acquisition systems in the future.