S1-Omni: A Unified Multimodal Reasoning Model for Scientific Understanding, Prediction, and Generation

We present S1-Omni, a unified multimodal reasoning model for scientific understanding, prediction, and generation. AI for Science (AI4S) has advanced significantly through domain-specific models, tool-augmented LLMs, and scientific language models. However, model capabilities remain highly fragmented, limiting the joint modeling of heterogeneous data, scientific laws, and expert knowledge. S1-Omni addresses this gap by consolidating these capabilities into a single, coherent scientific reasoning model. The architecture of S1-Omni is built upon three core components: unified representation of scientific data, natural-world knowledge alignment, and decoding for domain-specific tasks. First, S1-Omni maps natural-language instructions and scientific objects, including CIF, SMILES, protein sequences, spectra, and scientific images, into a shared representation space. Second, it incorporates scientific laws and expert knowledge into data construction and training, enabling the model to reason from scientific evidence. Third, it performs task-specific decoding to support a broad range of applications, including property prediction, spectrum-to-molecular generation, protein site and structure prediction, and scientific image generation and editing. S1-Omni is trained on S1-Omni-Corpus, which covers 200 scientific tasks and contains millions of reasoning samples, and is evaluated on over 60 scientific benchmarks. It outperforms GPT-5.5 and Gemini-3.1-Pro on most benchmarks and matches or surpasses domain-specific models on several benchmarks. Overall, S1-Omni provides a practical path toward unified scientific modeling.

S1-VL: Scientific Multimodal Reasoning Model with Thinking-with-Images

We present S1-VL, a multimodal reasoning model for scientific domains that natively supports two complementary reasoning paradigms: Scientific Reasoning, which relies on structured chain-of-thought, and Thinking-with-Images, which enables the model to actively manipulate images through Python code execution during reasoning. In the Thinking-with-Images mode, the model generates and executes image-processing code in a sandbox environment, obtains intermediate visual results, and continues reasoning in a multi-turn iterative manner. This design is particularly effective for challenging scenarios such as high-resolution scientific chart interpretation, microscopic image understanding, and geometry-assisted reasoning. To construct the training data, we collect scientific multimodal datasets spanning six disciplines: mathematics, physics, chemistry, astronomy, geography, and biology. We further develop a six-dimensional quality filtering framework for reasoning trajectories. To mitigate redundant, ineffective, and erroneous visual operations commonly found in existing datasets, we propose a multi-stage filtering pipeline together with an adaptive data routing strategy. This strategy converts samples with low visual information gain into pure Reasoning-mode data, enabling the model to learn when image operations are truly necessary. S1-VL is trained through a four-stage progressive pipeline: scientific multimodal SFT, Thinking-with-Images cold-start SFT, and two stages of reinforcement learning with SAPO. We build S1-VL-32B on top of Qwen3-VL-32B-Thinking and evaluate it on 13 benchmarks. Experimental results show that S1-VL-32B achieves state-of-the-art performance on all five Thinking-with-Images benchmarks, including HRBench-4K, HRBench-8K, MME-RealWorld-CN, MME-RealWorld-Lite, and V*, and outperforms compared systems on scientific reasoning benchmarks such as Physics and VRSBench.