Rec-Distill: An Industrial Distillation Pipeline for Large-Scale Recommendation Models

Large recommendation models have demonstrated substantial potential gains under scaling laws, yet these gains are difficult to realize in industrial recommendation systems because real-world deployment requires lightweight models with strict serving efficiency and latency guarantees. This creates a fundamental gap between offline model scaling and online deployment. In this work, we present Rec-Distill, an industrial distillation pipeline that transfers the performance gains of large-scale recommendation modeling to efficient serving models. Rec-Distill combines large-teacher scaling with student-side transfer optimization through decoupled training, black-box distillation, debiasing mechanism, and a hybrid batch-streaming pipeline for dynamic recommendation environments. Across multiple recommendation and advertising scenarios on real-world platforms, our framework scales teacher models up to 24B dense parameters and 20K behavior sequence length, while enabling lightweight students to recover a substantial portion of teacher gains, with distillation transferability exceeding 60% in the best setting. Extensive offline and online experiments further show that these transferred gains consistently translate into measurable business improvements under industrial constraints. These results demonstrate that Rec-Distill provides a practical framework for distilling large-scale recommendation models into deployable, cost-efficient serving systems, while also establishing a reliable path toward scaling recommendation models to even larger regimes in the future.

Chromosomal Structural Abnormality Diagnosis by Homologous Similarity

Pathogenic chromosome abnormalities are very common among the general population. While numerical chromosome abnormalities can be quickly and precisely detected, structural chromosome abnormalities are far more complex and typically require considerable efforts by human experts for identification. This paper focuses on investigating the modeling of chromosome features and the identification of chromosomes with structural abnormalities. Most existing data-driven methods concentrate on a single chromosome and consider each chromosome independently, overlooking the crucial aspect of homologous chromosomes. In normal cases, homologous chromosomes share identical structures, with the exception that one of them is abnormal. Therefore, we propose an adaptive method to align homologous chromosomes and diagnose structural abnormalities through homologous similarity. Inspired by the process of human expert diagnosis, we incorporate information from multiple pairs of homologous chromosomes simultaneously, aiming to reduce noise disturbance and improve prediction performance. Extensive experiments on real-world datasets validate the effectiveness of our model compared to baselines.