RaLMPH: Reliability-aware Learning for Multi-Pathologist Harmonization in Whole-Slide Image Classification

Multiple Instance Learning (MIL) is a standard paradigm for Whole-Slide Image (WSI) analysis and has achieved strong results in computational pathology. However, most MIL pipelines assume a single "gold" label per slide, which conflicts with clinical practice where substantial inter-pathologist variability is common. Existing multi-annotator learning and label-refinement methods typically estimate global annotator reliability or rely on single-instance assumptions, making them poorly suited to MIL and to localized diagnostic contexts where experts disagree. We propose RaLMPH (Reliability-aware Learning for Multi-Pathologist Harmonization), a MIL-based label reconciliation framework for WSIs annotated by multiple pathologists. RaLMPH introduces a reliability field that jointly models (i) local neighborhood structure in WSI feature space and (ii) expert uncertainty (entropy), enabling per-sample identification of trustworthy reference neighborhoods. Leveraging this field, RaLMPH performs sample-wise local annotator ranking to select reliable opinions per slide and applies an adaptive gating mechanism to fuse labels conditioned on local reliability. Experiments on a clinical WSI dataset with labels from six pathologists, as well as controlled simulated benchmarks, show that RaLMPH consistently outperforms existing approaches. Further analyses clarify how our reliability-aware mechanism improves label reconciliation and downstream MIL performance.

One Sequential Recommendation Model Pretrained from Synthetic Priors Predicts Multiple Datasets

Existing sequential recommendation models rely on dataset-specific training, where the learned parameters are fitted to the item catalog and the observed interaction distribution of the training data. This limits generalization to new domains, typically requiring retraining from scratch. In this work, we propose SRPFN, a Prior-data Fitted Network for sequential recommendation -- predicting the next item in a single forward pass without any gradient-based parameter updates in the target domain. SRPFN is pretrained offline on 25.6M sequences sampled from a synthetic prior that spans diverse item-to-item transition patterns, learning to produce posterior predictive next-item distributions. At inference time, SRPFN generates recommendations by conditioning on a support set of item-item transition examples from the target domain, adapting to domain-specific patterns without retraining. Extensive experiments on five benchmarks across 10 baselines show that SRPFN achieves the best or second-best performance across nearly all metrics and datasets, while being substantially more computationally efficient than trained baselines. These results establish that a single model pretrained on synthetic priors can generalize across diverse real-world domains, offering a framework for update-free sequential recommendation.

Every Preference Has Its Strength: Injecting Ordinal Semantics into LLM-Based Recommenders

Recent work has shown that large language models (LLMs) can enhance recommender systems by integrating collaborative filtering (CF) signals through hybrid prompting. However, most existing CF-LLM frameworks collapse explicit ratings into implicit or positive-only feedback, discarding the ordinal structure that conveys fine-grained preference strength. As a result, these models struggle to exploit graded semantics and nuanced preference distinctions. We propose Ordinal Semantic Anchoring (OSA), a hybrid CF-LLM framework that explicitly incorporates preference strength by modeling interaction-level user feedback. OSA represents ordinal preference levels as numeric textual tokens and uses their token embeddings as semantic anchors to align user-item interaction representations in the LLM latent space. Through strength-aware alignment across ordinal levels, OSA preserves preference semantics when integrating collaborative signals with LLMs. Experiments on multiple real-world datasets demonstrate that OSA consistently outperforms existing baselines, particularly in pairwise preference evaluation, highlighting its effectiveness in modeling fine-grained user preferences over prior CF-LLM methods.

Every Error has Its Magnitude: Asymmetric Mistake Severity Training for Multiclass Multiple Instance Learning

Multiple Instance Learning (MIL) has emerged as a promising paradigm for Whole Slide Image (WSI) diagnosis, offering effective learning with limited annotations. However, existing MIL frameworks overlook diagnostic priorities and fail to differentiate the severity of misclassifications in multiclass, leaving clinically critical errors unaddressed. We propose a mistake-severity-aware training strategy that organizes diagnostic classes into a hierarchical structure, with each level optimized using a severity-weighted cross-entropy loss that penalizes high-severity misclassifications more strongly. Additionally, hierarchical consistency is enforced through probabilistic alignment, a semantic feature remix applied to the instance bag to robustly train class priority and accommodate clinical cases involving multiple symptoms. An asymmetric Mikel's Wheel-based metric is also introduced to quantify the severity of errors specific to medical fields. Experiments on challenging public and real-world in-house datasets demonstrate that our approach significantly mitigates critical errors in MIL diagnosis compared to existing methods. We present additional experimental results on natural domain data to demonstrate the generalizability of our proposed method beyond medical contexts.

Large Language Models Are Better Logical Fallacy Reasoners with Counterargument, Explanation, and Goal-Aware Prompt Formulation

The advancement of Large Language Models (LLMs) has greatly improved our ability to process complex language. However, accurately detecting logical fallacies remains a significant challenge. This study presents a novel and effective prompt formulation approach for logical fallacy detection, applicable in both supervised (fine-tuned) and unsupervised (zero-shot) settings. Our method enriches input text incorporating implicit contextual information -- counterarguments, explanations, and goals -- which we query for validity within the context of the argument. We then rank these queries based on confidence scores to inform classification. We evaluate our approach across multiple datasets from 5 domains, covering 29 distinct fallacy types, using models from the GPT and LLaMA series. The results show substantial improvements over state-of-the-art models, with F1 score increases of up to 0.60 in zero-shot settings and up to 0.45 in fine-tuned models. Extensive analyses further illustrate why and how our method excels.

Universal Discrete Filtering with Lookahead or Delay

We consider the universal discrete filtering problem, where an input sequence generated by an unknown source passes through a discrete memoryless channel, and the goal is to estimate its components based on the output sequence with limited lookahead or delay. We propose and establish the universality of a family of schemes for this setting. These schemes are induced by universal Sequential Probability Assignments (SPAs), and inherit their computational properties. We show that the schemes induced by LZ78 are practically implementable and well-suited for scenarios with limited computational resources and latency constraints. In passing, we use some of the intermediate results to obtain upper and lower bounds that appear to be new, in the purely Bayesian setting, on the optimal filtering performance in terms, respectively, of the mutual information between the noise-free and noisy sequence, and the entropy of the noise-free sequence causally conditioned on the noisy one.

Fully Geometric Panoramic Localization

We introduce a lightweight and accurate localization method that only utilizes the geometry of 2D-3D lines. Given a pre-captured 3D map, our approach localizes a panorama image, taking advantage of the holistic 360 view. The system mitigates potential privacy breaches or domain discrepancies by avoiding trained or hand-crafted visual descriptors. However, as lines alone can be ambiguous, we express distinctive yet compact spatial contexts from relationships between lines, namely the dominant directions of parallel lines and the intersection between non-parallel lines. The resulting representations are efficient in processing time and memory compared to conventional visual descriptor-based methods. Given the groups of dominant line directions and their intersections, we accelerate the search process to test thousands of pose candidates in less than a millisecond without sacrificing accuracy. We empirically show that the proposed 2D-3D matching can localize panoramas for challenging scenes with similar structures, dramatic domain shifts or illumination changes. Our fully geometric approach does not involve extensive parameter tuning or neural network training, making it a practical algorithm that can be readily deployed in the real world. Project page including the code is available through this link: https://82magnolia.github.io/fgpl/.