Explainable AI as a Double-Edged Sword in Dermatology: The Impact on Clinicians versus The Public

Artificial intelligence (AI) is increasingly permeating healthcare, from physician assistants to consumer applications. Since AI algorithm's opacity challenges human interaction, explainable AI (XAI) addresses this by providing AI decision-making insight, but evidence suggests XAI can paradoxically induce over-reliance or bias. We present results from two large-scale experiments (623 lay people; 153 primary care physicians, PCPs) combining a fairness-based diagnosis AI model and different XAI explanations to examine how XAI assistance, particularly multimodal large language models (LLMs), influences diagnostic performance. AI assistance balanced across skin tones improved accuracy and reduced diagnostic disparities. However, LLM explanations yielded divergent effects: lay users showed higher automation bias - accuracy boosted when AI was correct, reduced when AI erred - while experienced PCPs remained resilient, benefiting irrespective of AI accuracy. Presenting AI suggestions first also led to worse outcomes when the AI was incorrect for both groups. These findings highlight XAI's varying impact based on expertise and timing, underscoring LLMs as a "double-edged sword" in medical AI and informing future human-AI collaborative system design.

Towards Privacy-Preserving and Heterogeneity-aware Split Federated Learning via Probabilistic Masking

Split Federated Learning (SFL) has emerged as an efficient alternative to traditional Federated Learning (FL) by reducing client-side computation through model partitioning. However, exchanging of intermediate activations and model updates introduces significant privacy risks, especially from data reconstruction attacks that recover original inputs from intermediate representations. Existing defenses using noise injection often degrade model performance. To overcome these challenges, we present PM-SFL, a scalable and privacy-preserving SFL framework that incorporates Probabilistic Mask training to add structured randomness without relying on explicit noise. This mitigates data reconstruction risks while maintaining model utility. To address data heterogeneity, PM-SFL employs personalized mask learning that tailors submodel structures to each client's local data. For system heterogeneity, we introduce a layer-wise knowledge compensation mechanism, enabling clients with varying resources to participate effectively under adaptive model splitting. Theoretical analysis confirms its privacy protection, and experiments on image and wireless sensing tasks demonstrate that PM-SFL consistently improves accuracy, communication efficiency, and robustness to privacy attacks, with particularly strong performance under data and system heterogeneity.

D-CoRP: Differentiable Connectivity Refinement for Functional Brain Networks

Brain network is an important tool for understanding the brain, offering insights for scientific research and clinical diagnosis. Existing models for brain networks typically primarily focus on brain regions or overlook the complexity of brain connectivities. MRI-derived brain network data is commonly susceptible to connectivity noise, underscoring the necessity of incorporating connectivities into the modeling of brain networks. To address this gap, we introduce a differentiable module for refining brain connectivity. We develop the multivariate optimization based on information bottleneck theory to address the complexity of the brain network and filter noisy or redundant connections. Also, our method functions as a flexible plugin that is adaptable to most graph neural networks. Our extensive experimental results show that the proposed method can significantly improve the performance of various baseline models and outperform other state-of-the-art methods, indicating the effectiveness and generalizability of the proposed method in refining brain network connectivity. The code will be released for public availability.

Hand-Object Interaction Controller (HOIC): Deep Reinforcement Learning for Reconstructing Interactions with Physics

Hand manipulating objects is an important interaction motion in our daily activities. We faithfully reconstruct this motion with a single RGBD camera by a novel deep reinforcement learning method to leverage physics. Firstly, we propose object compensation control which establishes direct object control to make the network training more stable. Meanwhile, by leveraging the compensation force and torque, we seamlessly upgrade the simple point contact model to a more physical-plausible surface contact model, further improving the reconstruction accuracy and physical correctness. Experiments indicate that without involving any heuristic physical rules, this work still successfully involves physics in the reconstruction of hand-object interactions which are complex motions hard to imitate with deep reinforcement learning. Our code and data are available at https://github.com/hu-hy17/HOIC.

Physical Interaction: Reconstructing Hand-object Interactions with Physics

Single view-based reconstruction of hand-object interaction is challenging due to the severe observation missing caused by occlusions. This paper proposes a physics-based method to better solve the ambiguities in the reconstruction. It first proposes a force-based dynamic model of the in-hand object, which not only recovers the unobserved contacts but also solves for plausible contact forces. Next, a confidence-based slide prevention scheme is proposed, which combines both the kinematic confidences and the contact forces to jointly model static and sliding contact motion. Qualitative and quantitative experiments show that the proposed technique reconstructs both physically plausible and more accurate hand-object interaction and estimates plausible contact forces in real-time with a single RGBD sensor.