Multi-site, Multi-domain Airway Tree Modeling (ATM'22): A Public Benchmark for Pulmonary Airway Segmentation

Open international challenges are becoming the de facto standard for assessing computer vision and image analysis algorithms. In recent years, new methods have extended the reach of pulmonary airway segmentation that is closer to the limit of image resolution. Since EXACT'09 pulmonary airway segmentation, limited effort has been directed to quantitative comparison of newly emerged algorithms driven by the maturity of deep learning based approaches and clinical drive for resolving finer details of distal airways for early intervention of pulmonary diseases. Thus far, public annotated datasets are extremely limited, hindering the development of data-driven methods and detailed performance evaluation of new algorithms. To provide a benchmark for the medical imaging community, we organized the Multi-site, Multi-domain Airway Tree Modeling (ATM'22), which was held as an official challenge event during the MICCAI 2022 conference. ATM'22 provides large-scale CT scans with detailed pulmonary airway annotation, including 500 CT scans (300 for training, 50 for validation, and 150 for testing). The dataset was collected from different sites and it further included a portion of noisy COVID-19 CTs with ground-glass opacity and consolidation. Twenty-three teams participated in the entire phase of the challenge and the algorithms for the top ten teams are reviewed in this paper. Quantitative and qualitative results revealed that deep learning models embedded with the topological continuity enhancement achieved superior performance in general. ATM'22 challenge holds as an open-call design, the training data and the gold standard evaluation are available upon successful registration via its homepage.

Semi-supervised learning based on generative adversarial network: a comparison between good GAN and bad GAN approach

Recently, semi-supervised learning methods based on generative adversarial networks (GANs) have received much attention. Among them, two distinct approaches have achieved competitive results on a variety of benchmark datasets. Bad GAN learns a classifier with unrealistic samples distributed on the complement of the support of the input data. Conversely, Triple GAN consists of a three-player game that tries to leverage good generated samples to boost classification results. In this paper, we perform a comprehensive comparison of these two approaches on different benchmark datasets. We demonstrate their different properties on image generation, and sensitivity to the amount of labeled data provided. By comprehensively comparing these two methods, we hope to shed light on the future of GAN-based semi-supervised learning.

Semi-supervised Rare Disease Detection Using Generative Adversarial Network

Rare diseases affect a relatively small number of people, which limits investment in research for treatments and cures. Developing an efficient method for rare disease detection is a crucial first step towards subsequent clinical research. In this paper, we present a semi-supervised learning framework for rare disease detection using generative adversarial networks. Our method takes advantage of the large amount of unlabeled data for disease detection and achieves the best results in terms of precision-recall score compared to baseline techniques.

Source-LDA: Enhancing probabilistic topic models using prior knowledge sources

A popular approach to topic modeling involves extracting co-occurring n-grams of a corpus into semantic themes. The set of n-grams in a theme represents an underlying topic, but most topic modeling approaches are not able to label these sets of words with a single n-gram. Such labels are useful for topic identification in summarization systems. This paper introduces a novel approach to labeling a group of n-grams comprising an individual topic. The approach taken is to complement the existing topic distributions over words with a known distribution based on a predefined set of topics. This is done by integrating existing labeled knowledge sources representing known potential topics into the probabilistic topic model. These knowledge sources are translated into a distribution and used to set the hyperparameters of the Dirichlet generated distribution over words. In the inference these modified distributions guide the convergence of the latent topics to conform with the complementary distributions. This approach ensures that the topic inference process is consistent with existing knowledge. The label assignment from the complementary knowledge sources are then transferred to the latent topics of the corpus. The results show both accurate label assignment to topics as well as improved topic generation than those obtained using various labeling approaches based off Latent Dirichlet allocation (LDA).