SignLlama: Enhancing Gloss-free Sign Language Translation by Prioritizing Visual Features for LLMs

Large Language Models (LLMs) have achieved remarkable success across a wide range of tasks. However, fine-tuning LLMs for Gloss-Free Sign Language Translation (GFSLT) remains a challenge. In this paper, we investigate how to effectively adapt LLMs to the GFSLT task. We show that there are two key issues that need to be solved: (1) the inherent distributional gap between visual feature inputs and text feature inputs makes it difficult for LLMs to interpret visual inputs; and (2) existing approaches typically concatenate visual and textual features in an autoregressive framework, which leads to the model overemphasizing textual inputs and deprioritizing visual cues, as LLMs are pretrained predominantly on text-centric data. To address the first challenge, we propose a simple yet effective method named Filtered Pseudo-Gloss CTC Pretraining, which leverages filtered pseudo-gloss sequences generated from text sequences to supervise the training of the visual backbone. To tackle the second issue, we introduce a Visual-Prioritized Distillation training strategy. Specifically, we define a visual-only prediction path in which text inputs are masked, and the model is required to generate the target sequence relying solely on visual inputs. To guide this path, the outputs from the standard visual-textual prediction are then distilled into the visual-only prediction path, encouraging the model to prioritize visual features. Comprehensive experiments and qualitative analyses demonstrate the effectiveness of the proposed model. The proposed SignLlama achieves very competitive performance on multiple datasets for GFSLT tasks, without using any extra modalities or external sign language datasets for pretraining.

ASTELD: A Six-Axis Classification Framework for Autonomous AI Agents - Design, Evaluation, and an OpenClaw Case Study

Autonomous AI agent platforms differ substantially in architecture, security, tool integration, execution, autonomy, and deployment, yet the field lacks a common classification scheme for comparing these design choices. We propose ASTELD, an operational six-axis classification framework for autonomous AI agents: Architecture pattern, Security posture, Tool integration model, Execution paradigm, Level of autonomy and human control, and Deployment topology. ASTELD is constructed by synthesizing prior agent taxonomies with observable platform properties and explicit category-assignment rules. We evaluate its discriminative and explanatory utility by mapping eight representative frameworks and by using OpenClaw as an in-depth case study. The resulting profiles separate all eight platforms under their dominant configurations and reveal three cross-platform patterns: a security-accessibility diagonal, strong execution-architecture coupling, and capability convergence with persistent architectural differentiation. We further classify 50+ OpenClaw derivatives and find that innovation concentrates on the Security, Execution, and Deployment axes, indicating that ASTELD can explain where ecosystem fragmentation occurs. The OpenClaw case study also supplies a six-category vulnerability taxonomy, evidence from five institutional assessments, and adoption and governance analyses that connect platform coordinates to observed risks. These results position ASTELD as a reproducible method for comparing agent platforms, identifying unoccupied design regions, guiding framework selection, and organizing future empirical research. The analysis also exposes a consequential empty region: none of the evaluated systems combines local-first deployment with enterprise-grade security.

EchoAgent: Towards Reliable Echocardiography Interpretation with "Eyes","Hands" and "Minds"

Reliable interpretation of echocardiography (Echo) is crucial for assessing cardiac function, which demands clinicians to synchronously orchestrate multiple capabilities, including visual observation (eyes), manual measurement (hands), and expert knowledge learning and reasoning (minds). While current task-specific deep-learning approaches and multimodal large language models have demonstrated promise in assisting Echo analysis through automated segmentation or reasoning, they remain focused on restricted skills, i.e., eyes-hands or eyes-minds, thereby limiting clinical reliability and utility. To address these issues, we propose EchoAgent, an agentic system tailored for end-to-end Echo interpretation, which achieves a fully coordinated eyes-hands-minds workflow that learns, observes, operates, and reasons like a cardiac sonographer. First, we introduce an expertise-driven cognition engine where our agent can automatically assimilate credible Echo guidelines into a structured knowledge base, thus constructing an Echo-customized mind. Second, we devise a hierarchical collaboration toolkit to endow EchoAgent with eyes-hands, which can automatically parse Echo video streams, identify cardiac views, perform anatomical segmentation, and quantitative measurement. Third, we integrate the perceived multimodal evidence with the exclusive knowledge base into an orchestrated reasoning hub to conduct explainable inferences. We evaluate EchoAgent on CAMUS and MIMIC-EchoQA datasets, which cover 48 distinct echocardiographic views spanning 14 cardiac anatomical regions. Experimental results show that EchoAgent achieves optimal performance across diverse structure analyses, yielding overall accuracy of up to 80.00%. Importantly, EchoAgent empowers a single system with abilities to learn, observe, operate and reason like an echocardiologist, which holds great promise for reliable Echo interpretation.

Diff-CXR: Report-to-CXR generation through a disease-knowledge enhanced diffusion model

Text-To-Image (TTI) generation is significant for controlled and diverse image generation with broad potential applications. Although current medical TTI methods have made some progress in report-to-Chest-Xray (CXR) generation, their generation performance may be limited due to the intrinsic characteristics of medical data. In this paper, we propose a novel disease-knowledge enhanced Diffusion-based TTI learning framework, named Diff-CXR, for medical report-to-CXR generation. First, to minimize the negative impacts of noisy data on generation, we devise a Latent Noise Filtering Strategy that gradually learns the general patterns of anomalies and removes them in the latent space. Then, an Adaptive Vision-Aware Textual Learning Strategy is designed to learn concise and important report embeddings in a domain-specific Vision-Language Model, providing textual guidance for Chest-Xray generation. Finally, by incorporating the general disease knowledge into the pretrained TTI model via a delicate control adapter, a disease-knowledge enhanced diffusion model is introduced to achieve realistic and precise report-to-CXR generation. Experimentally, our Diff-CXR outperforms previous SOTA medical TTI methods by 33.4\% / 8.0\% and 23.8\% / 56.4\% in the FID and mAUC score on MIMIC-CXR and IU-Xray, with the lowest computational complexity at 29.641 GFLOPs. Downstream experiments on three thorax disease classification benchmarks and one CXR-report generation benchmark demonstrate that Diff-CXR is effective in improving classical CXR analysis methods. Notably, models trained on the combination of 1\% real data and synthetic data can achieve a competitive mAUC score compared to models trained on all data, presenting promising clinical applications.