Deep Learning in Breast Cancer Imaging: A Decade of Progress and Future Directions

Breast cancer has reached the highest incidence rate worldwide among all malignancies since 2020. Breast imaging plays a significant role in early diagnosis and intervention to improve the outcome of breast cancer patients. In the past decade, deep learning has shown remarkable progress in breast cancer imaging analysis, holding great promise in interpreting the rich information and complex context of breast imaging modalities. Considering the rapid improvement in the deep learning technology and the increasing severity of breast cancer, it is critical to summarize past progress and identify future challenges to be addressed. In this paper, we provide an extensive survey of deep learning-based breast cancer imaging research, covering studies on mammogram, ultrasound, magnetic resonance imaging, and digital pathology images over the past decade. The major deep learning methods, publicly available datasets, and applications on imaging-based screening, diagnosis, treatment response prediction, and prognosis are described in detail. Drawn from the findings of this survey, we present a comprehensive discussion of the challenges and potential avenues for future research in deep learning-based breast cancer imaging.

Explicitly Modeled Attention Maps for Image Classification

Self-attention networks have shown remarkable progress in computer vision tasks such as image classification. The main benefit of the self-attention mechanism is the ability to capture long-range feature interactions in attention-maps. However, the computation of attention-maps requires a learnable key, query, and positional encoding, whose usage is often not intuitive and computationally expensive. To mitigate this problem, we propose a novel self-attention module with explicitly modeled attention-maps using only a single learnable parameter for low computational overhead. The design of explicitly modeled attention-maps using geometric prior is based on the observation that the spatial context for a given pixel within an image is mostly dominated by its neighbors, while more distant pixels have a minor contribution. Concretely, the attention-maps are parametrized via simple functions (e.g., Gaussian kernel) with a learnable radius, which is modeled independently of the input content. Our evaluation shows that our method achieves an accuracy improvement of up to 2.2% over the ResNet-baselines in ImageNet ILSVRC and outperforms other self-attention methods such as AA-ResNet152 (Bello et al., 2019) in accuracy by 0.9% with 6.4% fewer parameters and 6.7% fewer GFLOPs.