Multi-Scale Fusion Methodologies for Head and Neck Tumor Segmentation

Head and Neck (H\&N) organ-at-risk (OAR) and tumor segmentations are essential components of radiation therapy planning. The varying anatomic locations and dimensions of H\&N nodal Gross Tumor Volumes (GTVn) and H\&N primary gross tumor volume (GTVp) are difficult to obtain due to lack of accurate and reliable delineation methods. The downstream effect of incorrect segmentation can result in unnecessary irradiation of normal organs. Towards a fully automated radiation therapy planning algorithm, we explore the efficacy of multi-scale fusion based deep learning architectures for accurately segmenting H\&N tumors from medical scans.

An Efficient Multi-Scale Fusion Network for 3D Organ at Risk (OAR) Segmentation

Accurate segmentation of organs-at-risks (OARs) is a precursor for optimizing radiation therapy planning. Existing deep learning-based multi-scale fusion architectures have demonstrated a tremendous capacity for 2D medical image segmentation. The key to their success is aggregating global context and maintaining high resolution representations. However, when translated into 3D segmentation problems, existing multi-scale fusion architectures might underperform due to their heavy computation overhead and substantial data diet. To address this issue, we propose a new OAR segmentation framework, called OARFocalFuseNet, which fuses multi-scale features and employs focal modulation for capturing global-local context across multiple scales. Each resolution stream is enriched with features from different resolution scales, and multi-scale information is aggregated to model diverse contextual ranges. As a result, feature representations are further boosted. The comprehensive comparisons in our experimental setup with OAR segmentation as well as multi-organ segmentation show that our proposed OARFocalFuseNet outperforms the recent state-of-the-art methods on publicly available OpenKBP datasets and Synapse multi-organ segmentation. Both of the proposed methods (3D-MSF and OARFocalFuseNet) showed promising performance in terms of standard evaluation metrics. Our best performing method (OARFocalFuseNet) obtained a dice coefficient of 0.7995 and hausdorff distance of 5.1435 on OpenKBP datasets and dice coefficient of 0.8137 on Synapse multi-organ segmentation dataset.

Automatic Polyp Segmentation with Multiple Kernel Dilated Convolution Network

The detection and removal of precancerous polyps through colonoscopy is the primary technique for the prevention of colorectal cancer worldwide. However, the miss rate of colorectal polyp varies significantly among the endoscopists. It is well known that a computer-aided diagnosis (CAD) system can assist endoscopists in detecting colon polyps and minimize the variation among endoscopists. In this study, we introduce a novel deep learning architecture, named MKDCNet, for automatic polyp segmentation robust to significant changes in polyp data distribution. MKDCNet is simply an encoder-decoder neural network that uses the pre-trained ResNet50 as the encoder and novel multiple kernel dilated convolution (MKDC) block that expands the field of view to learn more robust and heterogeneous representation. Extensive experiments on four publicly available polyp datasets and cell nuclei dataset show that the proposed MKDCNet outperforms the state-of-the-art methods when trained and tested on the same dataset as well when tested on unseen polyp datasets from different distributions. With rich results, we demonstrated the robustness of the proposed architecture. From an efficiency perspective, our algorithm can process at (approx 45) frames per second on RTX 3090 GPU. MKDCNet can be a strong benchmark for building real-time systems for clinical colonoscopies. The code of the proposed MKDCNet is available at https://github.com/nikhilroxtomar/MKDCNet.

Video Capsule Endoscopy Classification using Focal Modulation Guided Convolutional Neural Network

Video capsule endoscopy is a hot topic in computer vision and medicine. Deep learning can have a positive impact on the future of video capsule endoscopy technology. It can improve the anomaly detection rate, reduce physicians' time for screening, and aid in real-world clinical analysis. CADx classification system for video capsule endoscopy has shown a great promise for further improvement. For example, detection of cancerous polyp and bleeding can lead to swift medical response and improve the survival rate of the patients. To this end, an automated CADx system must have high throughput and decent accuracy. In this paper, we propose FocalConvNet, a focal modulation network integrated with lightweight convolutional layers for the classification of small bowel anatomical landmarks and luminal findings. FocalConvNet leverages focal modulation to attain global context and allows global-local spatial interactions throughout the forward pass. Moreover, the convolutional block with its intrinsic inductive/learning bias and capacity to extract hierarchical features allows our FocalConvNet to achieve favourable results with high throughput. We compare our FocalConvNet with other SOTA on Kvasir-Capsule, a large-scale VCE dataset with 44,228 frames with 13 classes of different anomalies. Our proposed method achieves the weighted F1-score, recall and MCC} of 0.6734, 0.6373 and 0.2974, respectively outperforming other SOTA methodologies. Furthermore, we report the highest throughput of 148.02 images/second rate to establish the potential of FocalConvNet in a real-time clinical environment. The code of the proposed FocalConvNet is available at https://github.com/NoviceMAn-prog/FocalConvNet.

Challenges and Solutions to Build a Data Pipeline to Identify Anomalies in Enterprise System Performance

We discuss how VMware is solving the following challenges to harness data to operate our ML-based anomaly detection system to detect performance issues in our Software Defined Data Center (SDDC) enterprise deployments: (i) label scarcity and label bias due to heavy dependency on unscalable human annotators, and (ii) data drifts due to ever-changing workload patterns, software stack and underlying hardware. Our anomaly detection system has been deployed in production for many years and has successfully detected numerous major performance issues. We demonstrate that by addressing these data challenges, we not only improve the accuracy of our performance anomaly detection model by 30%, but also ensure that the model performance to never degrade over time.

PAANet: Progressive Alternating Attention for Automatic Medical Image Segmentation

Medical image segmentation can provide detailed information for clinical analysis which can be useful for scenarios where the detailed location of a finding is important. Knowing the location of disease can play a vital role in treatment and decision-making. Convolutional neural network (CNN) based encoder-decoder techniques have advanced the performance of automated medical image segmentation systems. Several such CNN-based methodologies utilize techniques such as spatial- and channel-wise attention to enhance performance. Another technique that has drawn attention in recent years is residual dense blocks (RDBs). The successive convolutional layers in densely connected blocks are capable of extracting diverse features with varied receptive fields and thus, enhancing performance. However, consecutive stacked convolutional operators may not necessarily generate features that facilitate the identification of the target structures. In this paper, we propose a progressive alternating attention network (PAANet). We develop progressive alternating attention dense (PAAD) blocks, which construct a guiding attention map (GAM) after every convolutional layer in the dense blocks using features from all scales. The GAM allows the following layers in the dense blocks to focus on the spatial locations relevant to the target region. Every alternate PAAD block inverts the GAM to generate a reverse attention map which guides ensuing layers to extract boundary and edge-related information, refining the segmentation process. Our experiments on three different biomedical image segmentation datasets exhibit that our PAANet achieves favourable performance when compared to other state-of-the-art methods.

GMSRF-Net: An improved generalizability with global multi-scale residual fusion network for polyp segmentation

Colonoscopy is a gold standard procedure but is highly operator-dependent. Efforts have been made to automate the detection and segmentation of polyps, a precancerous precursor, to effectively minimize missed rate. Widely used computer-aided polyp segmentation systems actuated by encoder-decoder have achieved high performance in terms of accuracy. However, polyp segmentation datasets collected from varied centers can follow different imaging protocols leading to difference in data distribution. As a result, most methods suffer from performance drop and require re-training for each specific dataset. We address this generalizability issue by proposing a global multi-scale residual fusion network (GMSRF-Net). Our proposed network maintains high-resolution representations while performing multi-scale fusion operations for all resolution scales. To further leverage scale information, we design cross multi-scale attention (CMSA) and multi-scale feature selection (MSFS) modules within the GMSRF-Net. The repeated fusion operations gated by CMSA and MSFS demonstrate improved generalizability of the network. Experiments conducted on two different polyp segmentation datasets show that our proposed GMSRF-Net outperforms the previous top-performing state-of-the-art method by 8.34% and 10.31% on unseen CVC-ClinicDB and unseen Kvasir-SEG, in terms of dice coefficient.

Exploiting Multi-Scale Fusion, Spatial Attention and Patch Interaction Techniques for Text-Independent Writer Identification

Text independent writer identification is a challenging problem that differentiates between different handwriting styles to decide the author of the handwritten text. Earlier writer identification relied on handcrafted features to reveal pieces of differences between writers. Recent work with the advent of convolutional neural network, deep learning-based methods have evolved. In this paper, three different deep learning techniques - spatial attention mechanism, multi-scale feature fusion and patch-based CNN were proposed to effectively capture the difference between each writer's handwriting. Our methods are based on the hypothesis that handwritten text images have specific spatial regions which are more unique to a writer's style, multi-scale features propagate characteristic features with respect to individual writers and patch-based features give more general and robust representations that helps to discriminate handwriting from different writers. The proposed methods outperforms various state-of-the-art methodologies on word-level and page-level writer identification methods on three publicly available datasets - CVL, Firemaker, CERUG-EN datasets and give comparable performance on the IAM dataset.

AGA-GAN: Attribute Guided Attention Generative Adversarial Network with U-Net for Face Hallucination

The performance of facial super-resolution methods relies on their ability to recover facial structures and salient features effectively. Even though the convolutional neural network and generative adversarial network-based methods deliver impressive performances on face hallucination tasks, the ability to use attributes associated with the low-resolution images to improve performance is unsatisfactory. In this paper, we propose an Attribute Guided Attention Generative Adversarial Network which employs novel attribute guided attention (AGA) modules to identify and focus the generation process on various facial features in the image. Stacking multiple AGA modules enables the recovery of both high and low-level facial structures. We design the discriminator to learn discriminative features exploiting the relationship between the high-resolution image and their corresponding facial attribute annotations. We then explore the use of U-Net based architecture to refine existing predictions and synthesize further facial details. Extensive experiments across several metrics show that our AGA-GAN and AGA-GAN+U-Net framework outperforms several other cutting-edge face hallucination state-of-the-art methods. We also demonstrate the viability of our method when every attribute descriptor is not known and thus, establishing its application in real-world scenarios.

An Efficient Anomaly Detection Approach using Cube Sampling with Streaming Data

Anomaly detection is critical in various fields, including intrusion detection, health monitoring, fault diagnosis, and sensor network event detection. The isolation forest (or iForest) approach is a well-known technique for detecting anomalies. It is, however, ineffective when dealing with dynamic streaming data, which is becoming increasingly prevalent in a wide variety of application areas these days. In this work, we extend our previous work by proposed an efficient iForest based approach for anomaly detection using cube sampling that is effective on streaming data. Cube sampling is used in the initial stage to choose nearly balanced samples, significantly reducing storage requirements while preserving efficiency. Following that, the streaming nature of data is addressed by a sliding window technique that generates consecutive chunks of data for systematic processing. The novelty of this paper is in applying Cube sampling in iForest and calculating inclusion probability. The proposed approach is equally successful at detecting anomalies as existing state-of-the-art approaches, requiring significantly less storage and time complexity. We undertake empirical evaluations of the proposed approach using standard datasets and demonstrate that it outperforms traditional approaches in terms of Area Under the ROC Curve (AUC-ROC) and can handle high-dimensional streaming data.